Reversal of P-glycoprotein-mediated multidrug resistance by a synthetic α-aminoxy peptidomimetic

International Journal of Pharmaceutics

Volumn 424, Issue 1-2, 2012, Pages 33-39

  Ma, Bin ^a   Chai, Stella ^a   Li, Na ^a   To, Kenneth K W ^a   Kan, Winnie Lai Ting ^a   Yang, Dan ^b   Lin, Ge ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Lysine peptidomimetic; Multidrug resistance reversal; P glycoprotein inhibitor

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ALPHA AMINOXYLYSINE PEPTIDOMIMETIC AGENT; DOXORUBICIN; GLYCOPROTEIN P; PEPTIDOMIMETIC AGENT; RHODAMINE 123; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ARTICLE; CYTOTOXICITY; DRUG MECHANISM; DRUG SELECTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; MOLECULAR INTERACTION; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATASES; ANTIBIOTICS, ANTINEOPLASTIC; CACO-2 CELLS; CELL LINE, TUMOR; CELL SURVIVAL; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FLUORESCENT DYES; HEK293 CELLS; HUMANS; LYSINE; P-GLYCOPROTEIN; PEPTIDOMIMETICS; RHODAMINE 123;

EID: 84863396516     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.12.046     Document Type: Article

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