Age-dependent changes in the cerebrospinal fluid proteome by slow off-rate modified aptamer array

American Journal of Pathology

Volumn 180, Issue 2, 2012, Pages 446-456

  Baird, Geoffrey S ^a,b   Nelson, Sally K ^c   Keeney, Tracy R ^c   Stewart, Alex ^c   Williams, Stephen ^c   Kraemer, Stephan ^c   Peskind, Elaine R ^d,e   Montine, Thomas J ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c SomaLogic Inc   (United States)

^d VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^e UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; APTAMER; BIOLOGICAL MARKER; PROTEOME; REAGENT;

ADULT; AGE; AGED; ARTICLE; BIOINFORMATICS; CEREBROSPINAL FLUID ANALYSIS; FEMALE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; MOLECULAR DYNAMICS; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MICROARRAY; SENSITIVITY AND SPECIFICITY; SLOW OFF RATE MODIFIED APTAMER ARRAY;

ADULT; AGED; AGED, 80 AND OVER; AGING; APTAMERS, NUCLEOTIDE; BIOLOGICAL MARKERS; CEREBROSPINAL FLUID PROTEINS; FEMALE; HUMANS; MALE; MIDDLE AGED; PROTEIN ARRAY ANALYSIS; PROTEOME; YOUNG ADULT;

EID: 84863395411     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.10.024     Document Type: Article

References (46)

1. J. Warren, J. Schott, N. Fox, M. Thom, T. Revesz, J. Holton, F. Scaravilli, D. Thomas, G. Plant, P. Rudge, M. Rossor Brain biopsy in dementia Brain 128 2005 2016 2025
2. P. Schneider, H. Hampel, K. Buerger Biological marker candidates of Alzheimer's disease in blood, plasma, and serum CNS Neurosci Ther 15 2009 358 374
3. M. Verbeek, D. De Jong, H. Kremer Brain-specific proteins in cerebrospinal fluid for the diagnosis of neurodegenerative diseases Ann Clin Biochem 40 2003 25 40
4. A. Fagan, D. Holtzman Cerebrospinal fluid biomarkers of Alzheimer's disease Biomarkers Med 4 2010 51 63
5. E. Peskind, A. Nordberg, T. Darreh-Shori, H. Soininen Safety of lumbar puncture procedures in patients with Alzheimer's disease Curr Alzheimer Res 6 2009 290 292
6. J. Wood Physiology, pharmacology, and dynamics of cerebrospinal fluid J. Wood, Neurobiology of Cerebrospinal Fluid 1980 Plenum Press New York 17 25
7. T. Milhorat Cerebrospinal fluid as a reflection of internal milieu of brain J. Wood, Neurobiology of Cerebrospinal Fluid 2 1983 Plenum Press New York 1 16
8. G. De Meyer, F. Shapiro, H. Vanderstichele, E. Vanmechelen, S. Engelborghs, P. De Deyn, E. Coart, O. Hansson, L. Minthon, H. Zetterberg, K. Blennow, L. Shaw, J. Trojanowski Initiative ftAsDN: Diagnosis-independent Alzheimer disease biomarker signature in cognitively normal elderly people Arch Neurol 67 2010 949 956
9. J. Zhang, I. Sokal, E. Peskind, J. Quinn, J. Jankovic, C. Kenney, K. Chung, S. Millard, J. Nutt, T. Montine CSF multianalyte profile distinguishes Alzheimer and Parkinson diseases Am J Clin Pathol 129 2008 526 529
10. G. Li, I. Sokal, J. Quinn, J. Leverenz, M. Brodey, G. Schellenberg, J. Kaye, M. Raskind, J. Zhang, E. Peskind, T. Montine CSF tau/Abeta42 ratio for increased risk of mild cognitive impairment: a follow-up study Neurology 69 2007 631 639
11. B.R. Wenner, M.A. Lovell, B.C. Lynn Proteomic analysis of human ventricular cerebrospinal fluid from neurologically normal, elderly subjects using two-dimensional LC-MS/MS J Proteome Res 3 2004 97 103
12. A. Sickmann, W. Dormeyer, S. Wortelkamp, D. Woitalla, W. Kuhn, H.E. Meyer Identification of proteins from human cerebrospinal fluid, separated by two-dimensional polyacrylamide gel electrophoresis Electrophoresis 21 2000 2721 2728
13. G. Maccarrone, D. Milfay, I. Birg, M. Rosenhagen, F. Holsboer, R. Grimm, J. Bailey, N. Zolotarjova, C.W. Turck Mining the human cerebrospinal fluid proteome by immunodepletion and shotgun mass spectrometry Electrophoresis 25 2004 2402 2412
14. X. Yuan, D.M. Desiderio Proteomics analysis of prefractionated human lumbar cerebrospinal fluid Proteomics 5 2005 541 550
15. S.E. Schutzer, T. Liu, B.H. Natelson, T.E. Angel, A.A. Schepmoes, S.O. Purvine, K.K. Hixson, M.S. Lipton, D.G. Camp, P.K. Coyle, R.D. Smith, J. Bergquist Establishing the proteome of normal human cerebrospinal fluid PLoS One 5 2010 e10980
16. S. Ebert, D. Phillips, P. Jenzewski, R. Nau, A. O'Connor, U. Michel Activin A concentrations in human cerebrospinal fluid are age-dependent and elevated in meningitis J Neurol Sci 250 2006 50 57
17. M. Kern, S. Bamborschke, M. Nekic, D. Schubert, C. Rydin, D. Lindholm, P. Schirmacher Concentrations of hepatocyte growth factor in cerebrospinal fluid under normal and different pathological conditions Cytokine 14 2001 170 176
18. D. Loeffler, C. Brickman, P. Juneau, M. Perry, N. Pomara, P. Lewitt Cerebrospinal fluid C3a increases with age, but does not increase further in Alzheimer's disease Neurobiol Aging 18 1997 555 557
19. J. Zhang, D. Goodlett, E. Peskind, J. Quinn, Y. Zhou, Q. Wang, C. Pan, E. Yi, J. Eng, R. Aebersold, T. Montine Quantitative proteomic analysis of age-related changes in human cerebrospinal fluid Neurobiol Aging 26 2005 207 227
20. S. Pan, R. Aebersold, R. Chen, J. Rush, D. Goodlett, M. McIntosh, J. Zhang, T. Brentnall Mass spectrometry based targeted protein quantification: methods and applications J Proteome Res 8 2009 787 797
21. R.F. Service Proteomics Proteomics ponders prime time Science 321 2008 1758 1761
22. J. Silberring, P. Ciborowski Biomarker discovery and clinical proteomics Trends Anal Chem 29 2010 128
23. P. Mitchell Proteomics retrenches Nature Biotechnol 28 2010 665 670
24. A.W. Bell, E.W. Deutsch, C.E. Au, R.E. Kearney, R. Beavis, S. Sechi, T. Nilsson, J.J. Bergeron, H.T.S.W. Group A HUPO test sample study reveals common problems in mass spectrometry-based proteomics Nat Methods 6 2009 423 430
25. R. Aebersold A stress test for mass spectrometry-based proteomics Nat Methods 6 2009 411 412
26. M.J. Taussig, U. Landegren Progress in antibody arrays Targets 2 2003 169 176
27. L. Gold, D. Ayers, J. Bertino, C. Bock, A. Bock, E.N. Brody, J. Carter, A.B. Dalby, B.E. Eaton, T. Fitzwater, D. Flather, A. Forbes, T. Foreman, C. Fowler, B. Gawande, M. Goss, M. Gunn, S. Gupta, D. Halladay, J. Heil, J. Heilig, B. Hicke, G. Husar, N. Janjic, T. Jarvis, S. Jennings, E. Katilius, T.R. Keeney, N. Kim, T.H. Koch, S. Kraemer, L. Kroiss, N. Le, D. Levine, W. Lindsey, B. Lollo, W. Mayfield, M. Mehan, R. Mehler, S.K. Nelson, M. Nelson, D. Nieuwlandt, M. Nikrad, U. Ochsner, R.M. Ostroff, M. Otis, T. Parker, S. Pietrasiewicz, D.I. Resnicow, J. Rohloff, G. Sanders, S. Sattin, D. Schneider, B. Singer, M. Stanton, A. Sterkel, A. Stewart, S. Stratford, J.D. Vaught, M. Vrkljan, J.J. Walker, M. Watrobka, S. Waugh, A. Weiss, S.K. Wilcox, A. Wolfson, S.K. Wolk, C. Zhang, D. Zichi Aptamer-based multiplexed proteomic technology for biomarker discovery PLoS One 5 2010 e15004
28. S. Kraemer, J. Vaught, C. Bock, L. Gold, E. Katilius, T. Keeney, N. Kim, N. Saccomano, S. Wilcox, D. Zichi, G. Sanders From SOMAmer-based biomarker discovery to diagnostic and clinical applications: A SOMAmer-based, streamlined multiplexed proteomic assay PLoS One 6 10 2011 e26332
29. M. Folstein, S. Folstein, P. McHugh Mini-mental state A practical method for grading the cognitive state of patients for the clinician J Psychiatr Res 12 1975 189 198
30. W. Wechsler Wechsler Memory ScaleRevised 1987 Psychological Corporation San Antonio, TX
31. S. Craft, J. Newcomer, S. Kanne, S. Dagogo-Jack, P. Cryer, Y. Sheline, J. Luby, A. Dagogo-Jack, A. Alderson Memory improvement following induced hyperinsulinemia in Alzheimer's disease Neurobiol Aging 17 1996 123 130
32. R. Reitan, D. Wolfson The Halstead-Reitan neuropsychological test battery D. Wedding, The Neuropsychology Handbook: Behavioral and Clinical Perspectives 1986 Springer New York 134 160
33. E. Peskind, R. Riekse, J. Quinn, J. Kaye, C. Clark, M. Farlow, C. Decarli, C. Chabal, D. Vavrek, M. Raskind, D. Galasko Safety and acceptability of the research lumbar puncture Alzheimer Dis Assoc Disord 19 2005 220 225
34. M. Nicolau, R. Tibshirani, A. Børresen-Dale, S. Jeffrey Disease-specific genomic analysis: identifying the signature of pathologic biology Bioinformatics 23 2007 957 965
35. R. Coppola, D. Mari, A. Lattuada, C. Franceschi Von Willebrand factor in Italian centenarians Haematologica 88 2003 39 43
36. A. Clerico, A. Fortunato, A. Ripoli, C. Prontera, G.C. Zucchelli, M. Emdin Distribution of plasma cardiac troponin I values in healthy subjects: pathophysiological considerations Clin Chem Lab Med 46 2008 804 808
37. M.C. Odden, I.B. Tager, R.T. Gansevoort, S.J. Bakker, R. Katz, L.F. Fried, A.B. Newman, R.B. Canada, T. Harris, M.J. Sarnak, D. Siscovick, M.G. Shlipak Age and cystatin C in healthy adults: a collaborative study Nephrol Dial Transplant 25 2010 463 469
38. C.J. Wilson, C.E. Finch, H.J. Cohen Cytokines and cognitionthe case for a head-to-toe inflammatory paradigm J Am Geriatr Soc 50 2002 2041 2056
39. A.M. Bodles, S.W. Barger Cytokines and the aging brainwhat we don't know might help us Trends Neurosci 27 2004 621 626
40. R. Garcia-Navarrete, E. Garcia, O. Arrieta, J. Sotelo Hepatocyte growth factor in cerebrospinal fluid is associated with mortality and recurrence of glioblastoma, and could be of prognostic value J Neurooncol 97 2010 347 351
41. R. Nanba, S. Kuroda, T. Ishikawa, K. Houkin, Y. Iwasaki Increased expression of hepatocyte growth factor in cerebrospinal fluid and intracranial artery in moyamoya disease Stroke 35 2004 2837 2842
42. C. Sy, H. Tsai, S. Wann, S. Lee, Y. Liu, Y. Chen Cerebrospinal fluid hepatocyte growth factor level in meningitis J Microbiol Immunol Infect 41 2008 301 306
43. F. Wen, S. Yu A study on the content of CSF vWF in patients with cerebral infarction at different location Thromb Haemost 88 2002 1067 1068
44. M. Pashenkov, M. Sderstrm, H. Link Secondary lymphoid organ chemokines are elevated in the cerebrospinal fluid during central nervous system inflammation J Neuroimmunol 135 2003 154 160
45. R. Press, M. Pashenkov, J. Jin, H. Link Aberrated levels of cerebrospinal fluid chemokines in Guillain-Barr syndrome and chronic inflammatory demyelinating polyradiculoneuropathy J Clin Immunol 23 2003 259 267
46. D. Amin, D. Ngoyi, G. Nhkwachi, M. Palomba, M. Rottenberg, P. Bscher, K. Kristensson, W. Masocha Identification of stage biomarkers for human African trypanosomiasis Am J Trop Med Hyg 82 2010 983 990