The combined treatment of praziquantel with osteopontin immunoneutralization reduces liver damage in Schistosoma japonicum-infected mice

Parasitology

Volumn 139, Issue 4, 2012, Pages 522-529

  Chen, Bo Lin ^a   Zhang, Gui Ying ^a   Wang, Shi Ping ^b   Li, Qian ^a   Xu, Mei Hua ^a   Shen, Yue Ming ^c   Yan, Lu ^a   Gu, Huan ^a   Li, Jia ^a   Huang, Y L ^d   Mu, Yi Bing ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c CHANGSHA CENTRAL HOSPITAL   (China)

^d UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

antibody; BALB C mice; granuloma; liver fibrosis; osteopontin; Schistosoma japonicum

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLCHICINE; COLLAGEN; NEUTRALIZING ANTIBODY; OSTEOPONTIN; OSTEOPONTIN ANTIBODY; PRAZIQUANTEL; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CERCARIA; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER FIBROSIS; LIVER GRANULOMA; LIVER INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHISTOSOMA JAPONICUM; SCHISTOSOMIASIS; SCHISTOSOMIASIS JAPONICA; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, NEUTRALIZING; ARTERIOSCLEROSIS; DRUG THERAPY, COMBINATION; FEMALE; GRANULOMA; IMMUNOLOGIC DEFICIENCY SYNDROMES; LIVER; LIVER CIRRHOSIS; MICE; MICE, INBRED BALB C; NEPHROTIC SYNDROME; OSTEOCHONDRODYSPLASIAS; OSTEOPONTIN; PRAZIQUANTEL; PULMONARY EMBOLISM; SCHISTOSOMA JAPONICUM; SCHISTOSOMIASIS JAPONICA; TRANSFORMING GROWTH FACTOR BETA1; TREATMENT OUTCOME;

MUS; SCHISTOSOMA; SCHISTOSOMA JAPONICUM;

EID: 84863376470     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182011002241     Document Type: Article

References (30)

1. Anthony, B., Allen, J. T., Li, Y. S. and McManus, D. P. (2010). Hepatic stellate cells and parasite-induced liver fibrosis. Parasites & Vectors 3, 60. doi: 10.1186/1756-3305-3-60.
2. Bartley, P. B., Ramm, G. A., Jones, M. K., Ruddell, R. G., Li, Y. and McManus, D. P. (2006). A contributory role for activated hepatic stellate cells in the dynamics of Schistosoma japonicum egg-induced fibrosis. International Journal for Parasitology 36, 993-1001. doi: 10.1016/j.ijpara. 2006.04.015.
3. Bergquist, R. and Tanner, M. (2010). Controlling schistosomiasis in Southeast Asia: a tale of two countries. Advances in Parasitology 72, 109-144. doi: 10.1016/S0065-308X(10)72005-4.
4. Burke, M. L., Jones, M. K., Gobert, G. N., Li, Y. S., Ellis, M. K. and McManus, D. P. (2009). Immunopathogenesis of human schistosomiasis. Parasite Immunology 31, 163-176. doi: 10.1111/j.1365-3024.2009.01098.x.
5. Chabas, D. (2005). Osteopontin, a multi-faceted molecule. Medecine Sciences (Paris) 21, 832-888. doi: 10.1051/medsci/20052110832.
6. Chapadeiro, E. and Pitanga, L. C. (1996). On the reversal of schistosomiasis hepatic fibrosis after specific therapy. Histopathologic study. Revista da Sociedade Brasileira de Medicina Tropical 30, 53-56.
7. Chen, B. L., Zhang, G. Y., Yuan, W. J., Wang, S. P., Shen, Y. M., Yan, L., Gu, H. and Li, J. (2011). Osteopontin expression is associated with hepatopathologic changes in Schistosoma japonicum-infected mice. World Journal of Gastroenterology 17, 5075-5082.
8. Coutinho, H. M., Acosta, L. P., Wu, H.W., McGarvey, S. T., Su, L., Langdon, G. C., Jiz, M. A., Jarilla, B., Olveda, R. M., Friedman, J. F. and Kurtis, J. D. (2007). Th2 cytokines are associated with persistent hepatic fibrosis in human Schistosoma japonicum infection. The Journal of Infectious Diseases 195, 288-295. doi: 10.1086/510313.
9. Doenhoff, M. J., Kusel, J. R., Coles, G. C. and Cioli, D. (2002). Resistance of Schistosoma mansoni to praziquantel: is there a problem? Transactions of the Royal Society of Tropical Medicine and Hygiene 96, 465-469.
10. Fornari, A., Rhoden, E. L., Zettler, C. G., Ribeiro, E. P. and Rhoden, C. R. (2011). Effects of the chronic use of finasteride and doxazosin mesylate on the histomorphometric characteristics of the prostate: experimental study in rats. International Urology and Nephrology 43, 39-45. doi: 10.1007/s11255-010- 9770-3.
11. Gabele, E., Brenner, D. A. and Rippe, R. A. (2003). Liver fibrosis: signals leading to the amplification of the fibrogenic hepatic stellate cell. Frontiers in Bioscience 8, 69-77. doi: 10.2741/887.
12. Garjito, T. A., Sudomo, M., Abdullah, Dahlan, M. and Nurwidayati, A. (2008). Schistosomiasis in Indonesia: past and present. Parasitology International 57, 277-280. doi: 10.1016/j.parint.2008.04.008.
13. Giachelli, C. M. and Steitz, S. (2000). Osteopontin: A versatile regulator of inflammation and biomineralization. Matrix Biology 19, 615-622. doi: 10.1016/S0945-053X(00)00108-6.
14. Gryseels, B., Polman, K., Clerinx, J. and Kestens, L. (2006). Human schistosomiasis. The Lancet 368, 1106-1118. doi: 10.1016/S0140-6736(06) 69440-3.
15. Kiefer, F.W., Zeyda, M., Gollinger, K., Pfau, B., Neuhofer, A., Weichhart, T., Säemann, M. D., Geyeregger, R., Schlederer, M., Kenner, L. and Stulnig, T. M. (2010). Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance. Diabetes 59, 935-946. doi: 10.2337/db09-0404.
16. Lenga, Y., Koh, A., Perera, A. S., McCulloch, C. A., Sodek, J. and Zohar, R. (2008). Osteopontin expression is required for myofibroblast differentiation. Circulation Research 102, 319-327. doi: 10.1161/circresaha. 107.160408.
17. Lorena, D., Darby, I. A., Gadeau, A. P., Leen, L. L., Rittling, S., Porto, L. C., Rosenbaum, J. and Desmoulière, A. (2006). Osteopontin expression in normal and fibrotic liver. Altered liver healing in osteopontindeficient mice. Journal of Hepatology 44, 383-390. doi:10.1016/ j.jhep.2005.07.024.
18. McManus, D. P., Li, Y., Gray, D. J. and Ross, A. G. (2009). Conquering 'snail fever': schistosomiasis and its control in China. Expert Review of Antiinfective Therapy 7, 473-485. doi: 10.1586/eri.09.17.
19. Moreira, R. K. (2007). Hepatic stellate cells and liver fibrosis. Archives of Pathology & Laboratory Medicine 131, 1728-1734.
20. Morimoto, J., Kon, S., Matsui, Y. and Uede, T. (2010). Osteopontin; as a target molecule for the treatment of inflammatory diseases. Current Drug Targets 11, 494-505.
21. O'Regan, A. and Berman, J. S. (2000). Osteopontin: A key cytokine in cell mediated and granulomatous inflammation. International Journal of Experimental Pathology 81, 373-390. doi: 10.1046/j.1365-2613.2000.00163.x.
22. Paiva, L. A., Maya-Monteiro, C. M., Bandeira-Melo, C., Silva, P. M., El-Cheikh, M. C., Teodoro, A. J., Borojevic, R., Perez, S. A. and Bozza, P. T. (2010). Interplay of cysteinyl leukotrienes and TGF-ß in the activation of hepatic stellate cells from Schistosoma mansoni granulomas. Biochimica et Biophysica Acta 1801, 1341-1348. doi: 10.1016/j.bbalip.2010. 08.014.
23. Ramaiah, S. K. and Rittling, S. (2008). Pathophysiological role of osteopontin in hepatic inflammation, toxicity, and cancer. Toxicological Sciences 103, 4-13. doi: 10.1093/toxsci/kfm246.
24. Reeves, H. L. and Friedman, S. L. (2002). Activation of hepatic stellate cells-A key issue in liver fibrosis. Frontiers in Bioscience 7, d808-d826. doi: 10.2741/reeves.
25. Shimada, M., Kirinoki, M., Shimizu, K., Kato-Hayashi, N., Chigusa, Y., Kitikoon, V., Pongsasakulchoti, P. and Matsuda, H. (2010). Characteristics of granuloma formation and liver fibrosis in murine schistosomiasis mekongi: a morphological comparison between Schistosoma mekongi and S. japonicum infection. Parasitology 137, 1781-1789. doi: 10.1017/S0031182010000806.
26. Singh, M., Foster, C. R., Dalal, S. and Singh, K. (2010). Osteopontin: role in extracellular matrix deposition and myocardial remodeling post-MI. Journal of Molecular and Cellular Cardiology 48, 538-543. doi: 10.1016/ j.yjmcc.2009.06.015.
27. Ueno, T., Miyazaki, E., Ando, M., Nureki, S. and Kumamoto, T. (2010). Osteopontin levels are elevated in patients with eosinophilic pneumonia. Respirology 15, 1111-1121. doi: 10.1111/j.1440-1843.2010. 01825.x.
28. von Lichtenberg, F. V. (1962). Host response to eggs of S. mansoni. I. Granuloma formation in the unsensitized laboratory mouse. The American Journal of Pathology 41, 711-731.
29. Wada, W., Kuwano, H., Hasegawa, Y. and Kojima, I. (2004). The dependence of transforming growth factor-beta-induced collagen production on autocrine factor activin A in hepatic stellate cells. Endocrinology 145, 2753-2759. doi: 10.1210/en.2003-1663.
30. Xu, X., Wen, X., Chi, Y., He, L., Zhou, S., Wang, X., Zhao, J., Liu, F. and Su, C. (2010). Activation-induced T helper cell death contributes to Th1/Th2 polarization following murine Schistosoma japonicum infection. Journal of Biomedicine and Biotechnology 2010, 202397. doi: 10.1155/2010/ 202397.