Mapping structural determinants within third intracellular loop that direct signaling specificity of type 1 corticotropin-releasing hormone receptor

Journal of Biological Chemistry

Volumn 287, Issue 12, 2012, Pages 8974-8985

  Punn, Anu ^a   Chen, Jing ^a   Delidaki, Maria ^a   Tang, Jiyou ^a   Liapakis, George ^b   Lehnert, Hendrik ^a,c   Levine, Michael A ^d   Grammatopoulos, Dimitris K ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF CRETE   (Greece)

^c UNIVERSITY OF LÜBECK   (Germany)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ENDOCRINOLOGY; PROTEINS; SIGNALING;

ALIPHATIC AMINO ACIDS; BIOLOGICAL RESPONSE; CORTICOTROPIN-RELEASING HORMONE; G PROTEIN ACTIVATION; HIGH AFFINITY BINDING; SIGNALING ACTIVITY; STRUCTURAL DETERMINANTS; THIRD INTRACELLULAR LOOPS;

CHEMICAL ACTIVATION;

ADENYLATE CYCLASE; ALANINE; ARGININE; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CYCLIC AMP; GQ PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL TRISPHOSPHATE; LYSINE; METHIONINE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PERTUSSIS TOXIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIGAND BINDING; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; THIRD INTRACELLULAR LOOP; WILD TYPE;

EID: 84863373198     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.272161     Document Type: Article

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