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Volumn 29, Issue 5, 2012, Pages 1012-1027

Development and characterization of a novel rat model of cervical spondylotic myelopathy: The impact of chronic cord compression on clinical, neuroanatomical, and neurophysiological outcomes

Author keywords

cervical spondylotic myelopathy; chronic compression; micro CT; rat model; spinal cord

Indexed keywords

TITANIUM;

EID: 84863369604     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2010.1709     Document Type: Article
Times cited : (43)

References (30)
  • 2
    • 34748859137 scopus 로고    scopus 로고
    • Clinical and MRI predictors of outcome after surgical intervention for cervical spondylotic myelopathy
    • DOI 10.1111/j.1552-6569.2007.00119.x
    • Alafifi, T., Kern, R., and Fehlings, M. (2007). Clinical and MRI predictors of outcome after surgical intervention for cervical spondylotic myelopathy. J. Neuroimaging 17, 315-322. (Pubitemid 47481066)
    • (2007) Journal of Neuroimaging , vol.17 , Issue.4 , pp. 315-322
    • Alafifi, T.1    Kern, R.2    Fehlings, M.3
  • 3
    • 33751120151 scopus 로고    scopus 로고
    • Pathophysiology of cervical myelopathy
    • Baptiste, D.C., and Fehlings, M.G. (2006). Pathophysiology of cervical myelopathy. Spine J. 6, 190S-197S.
    • (2006) Spine J , vol.6
    • Baptiste, D.C.1    Fehlings, M.G.2
  • 4
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • Basso, D.M., Beattie, M.S., and Bresnahan, J.C. (1995). A sensitive and reliable locomotor rating scale for open field testing in rats. J. Neurotrauma 12, 1-21.
    • (1995) J. Neurotrauma , vol.12 , pp. 1-21
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 5
    • 0023765010 scopus 로고
    • The pathophysiology of cervical spondylosis and myelopathy
    • Bohlman, H.H., and Emery, S.E. (1988). The pathophysiology of cervical spondylosis and myelopathy. Spine 13, 843-846.
    • (1988) Spine , vol.13 , pp. 843-846
    • Bohlman, H.H.1    Emery, S.E.2
  • 7
    • 0024406372 scopus 로고
    • A dose-response study of dexamethasone in a model of spinal cord compression caused by epidural tumor
    • Delattre, J.Y., Arbit, E., Thaler, H.T., Rosenblum, M.K., and Posner, J.B. (1989). A dose-response study of dexamethasone in a model of spinal cord compression caused by epidural tumor. J. Neurosurg. 70, 920-925. (Pubitemid 19150512)
    • (1989) Journal of Neurosurgery , vol.70 , Issue.6 , pp. 920-925
    • Delattre, J.Y.1    Arbit, E.2    Thaler, H.T.3    Rosenblum, M.K.4    Posner, J.B.5
  • 8
    • 51349136202 scopus 로고    scopus 로고
    • Value of so-matosensory evoked potentials in diagnosis, surgical monitoring and prognosis of cervical spondylotic myelopathy
    • Ding, Y., Hu, Y., Ruan, D.K., and Chen, B. (2008). Value of so-matosensory evoked potentials in diagnosis, surgical monitoring and prognosis of cervical spondylotic myelopathy. Chin. Med. J. (Engl.) 121, 1374-1378.
    • (2008) Chin. Med. J. (Engl.) , vol.121 , pp. 1374-1378
    • Ding, Y.1    Hu, Y.2    Ruan, D.K.3    Chen, B.4
  • 9
    • 0033559941 scopus 로고    scopus 로고
    • The optimal radiologic method for assessing spinal canal compromise and cord compression in patients with cervical spinal cord injury: Part II: Results of a multicenter study
    • DOI 10.1097/00007632-199903150-00023
    • Fehlings, M.G., Rao, S.C., Tator, C.H., Skaf, G., Arnold, P., Benzel, E., Dickman, C., Cuddy, B., Green, B., Hitchon, P., Northrup, B., Sonntag, V., Wagner, F., and Wilberger, J. (1999). The optimal radiologic method for assessing spinal canal compromise and cord compression in patients with cervical spinal cord injury. Part II: Results of a multicenter study. Spine (Phila. Pa. 1976) 24, 605-613. (Pubitemid 29136057)
    • (1999) Spine , vol.24 , Issue.6 , pp. 605-613
    • Fehlings, M.G.1    Rao, S.C.2    Tator, C.H.3    Skaf, G.4    Arnold, P.5    Benzel, E.6    Dickman, C.7    Cuddy, B.8    Green, B.9    Hitchon, P.10    Northrup, B.11    Sonntag, V.12    Wagner, F.13    Wilberger, J.14
  • 10
    • 0032535533 scopus 로고    scopus 로고
    • A review of the pathophysiology of cervical spondylotic myelopathy with insights for potential novel mechanisms drawn from traumatic spinal cord injury
    • DOI 10.1097/00007632-199812150-00012
    • Fehlings, M.G., and Skaf, G. (1998). A review of the patho-physiology of cervical spondylotic myelopathy with insights for potential novel mechanisms drawn from traumatic spinal cord injury. Spine (Phila. Pa. 1976) 23, 2730-2737. (Pubitemid 29013985)
    • (1998) Spine , vol.23 , Issue.24 , pp. 2730-2737
    • Fehlings, M.G.1    Skaf, G.2
  • 11
    • 0029012783 scopus 로고
    • The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury
    • Fehlings, M.G., and Tator, C.H. (1995). The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury. Exp. Neurol. 132, 220-228.
    • (1995) Exp. Neurol. , vol.132 , pp. 220-228
    • Fehlings, M.G.1    Tator, C.H.2
  • 12
    • 34547437661 scopus 로고    scopus 로고
    • Measurement of the vertebral canal dimensions of the neck of the rat with a comparison to the human
    • Flynn, J.R., and Bolton, P.S. (2007). Measurement of the vertebral canal dimensions of the neck of the rat with a comparison to the human. Anat. Rec. (Hoboken) 290, 893-899.
    • (2007) Anat. Rec. (Hoboken) , vol.290 , pp. 893-899
    • Flynn, J.R.1    Bolton, P.S.2
  • 13
    • 43049102039 scopus 로고    scopus 로고
    • Prognostic value of somatosensory-evoked potentials in the surgical management of cervical spondylotic myelopathy
    • DOI 10.1097/BRS.0b013e31816f6c8e, PII 0000763220080501000025
    • Hu, Y., Ding, Y., Ruan, D., Wong, Y.W., Cheung, K.M., and Luk, K.D. (2008). Prognostic value of somatosensory-evoked potentials in the surgical management of cervical spondylotic myelopathy. Spine (Phila. Pa. 1976) 33, E305-E310. (Pubitemid 351630235)
    • (2008) Spine , vol.33 , Issue.10
    • Hu, Y.1    Ding, Y.2    Ruan, D.3    Wong, Y.W.4    Cheung, K.M.C.5    Luk, K.D.K.6
  • 14
    • 0018913869 scopus 로고
    • Edema and circulatory disturbance in the spinal cord compressed by epidural neoplasms in rabbits
    • Ikeda, H., Ushio, Y., Hayakawa, T., and Mogami, H. (1980). Edema and circulatory disturbance in the spinal cord compressed by epidural neoplasms in rabbits. J. Neurosurg. 52, 203-209. (Pubitemid 10211978)
    • (1980) Journal of Neurosurgery , vol.52 , Issue.2 , pp. 203-209
    • Ikeda, H.1    Ushio, Y.2    Hayakawa, T.3    Mogami, H.4
  • 15
    • 74249106986 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and its receptors contribute to apoptosis of oligodendrocytes in the spinal cord of spinal hyperostotic mouse (twy/twy) sustaining chronic mechanical compression
    • Inukai, T., Uchida, K., Nakajima, H., Yayama, T., Kobayashi, S., Mwaka, E.S., Guerrero, A.R., and Baba, H. (2009). Tumor necrosis factor-alpha and its receptors contribute to apoptosis of oligodendrocytes in the spinal cord of spinal hyperostotic mouse (twy/twy) sustaining chronic mechanical compression. Spine (Phila. Pa. 1976) 34, 2848-2857.
    • (2009) Spine (Phila. Pa. 1976) , vol.34 , pp. 2848-2857
    • Inukai, T.1    Uchida, K.2    Nakajima, H.3    Yayama, T.4    Kobayashi, S.5    Mwaka, E.S.6    Guerrero, A.R.7    Baba, H.8
  • 16
    • 0032961704 scopus 로고    scopus 로고
    • Shape differences in the cervical and upper thoracic vertebrae in rats (Rattus norvegicus) and bats (Pteropus poiocephalus): Can we see shape patterns derived from position in column and species membership?
    • DOI 10.1017/S0021878298004634
    • Johnson, D.R., McAndrew, T.J., and Oguz, O. (1999). Shape differences in the cervical and upper thoracic vertebrae in rats (Rattus norvegicus) and bats (Pteropus poiocephalus): can we see shape patterns derived from position in column and species membership? J. Anat. 194 (Pt. 2), 249-253. (Pubitemid 29191844)
    • (1999) Journal of Anatomy , vol.194 , Issue.2 , pp. 249-253
    • Johnson, D.R.1    McAndrew, T.J.2    Oguz, O.3
  • 17
    • 1642289614 scopus 로고    scopus 로고
    • Delayed Myelopathy Induced by Chronic Compression in the Rat Spinal Cord
    • DOI 10.1002/ana.20018
    • Kim, P., Haisa, T., Kawamoto, T., Kirino, T., and Wakai, S. (2004). Delayed myelopathy induced by chronic compression in the rat spinal cord. Ann. Neurol. 55, 503-511. (Pubitemid 38391967)
    • (2004) Annals of Neurology , vol.55 , Issue.4 , pp. 503-511
    • Kim, P.1    Haisa, T.2    Kawamoto, T.3    Kirino, T.4    Wakai, S.5
  • 19
    • 0029833393 scopus 로고    scopus 로고
    • Cervical spon-dylosis. An update
    • McCormack, B.M., and Weinstein, P.R. (1996). Cervical spon-dylosis. An update. West J. Med. 165, 43-51.
    • (1996) West J. Med. , vol.165 , pp. 43-51
    • McCormack, B.M.1    Weinstein, P.R.2
  • 20
    • 8444235981 scopus 로고    scopus 로고
    • T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats
    • DOI 10.1016/j.neuroscience.2004.08.035, PII S0306452204007407
    • Moalem, G., Xu, K., and Yu, L. (2004). T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats. Neuroscience 129, 767-777. (Pubitemid 39487128)
    • (2004) Neuroscience , vol.129 , Issue.3 , pp. 767-777
    • Moalem, G.1    Xu, K.2    Yu, L.3
  • 21
    • 0030914701 scopus 로고    scopus 로고
    • A prospective survey of the causes of non-traumatic spastic paraparesis and tetraparesis in 585 patients
    • Moore, A.P., and Blumhardt, L.D. (1997). A prospective survey of the causes of non-traumatic spastic paraparesis and tetra-paresis in 585 patients. Spinal Cord 35, 361-367. (Pubitemid 27271839)
    • (1997) Spinal Cord , vol.35 , Issue.6 , pp. 361-367
    • Moore, A.P.1    Blumhardt, L.D.2
  • 23
    • 0017650830 scopus 로고
    • Objective clinical assessment of motor function after experimental spinal cord injury in the rat
    • Rivlin, A.S., and Tator, C.H. (1977). Objective clinical assessment of motor function after experimental spinal cord injury in the rat. J. Neurosurg. 47, 577-581. (Pubitemid 8193904)
    • (1977) Journal of Neurosurgery , vol.47 , Issue.4 , pp. 577-581
    • Rivlin, A.S.1    Tator, C.H.2
  • 24
    • 0036453979 scopus 로고    scopus 로고
    • Mechanisms of signal change during intraoperative somatosensory evoked potential monitoring of the spinal cord
    • Seyal, M., and Mull, B. (2002). Mechanisms of signal change during intraoperative somatosensory evoked potential monitoring of the spinal cord. J. Clin. Neurophysiol. 19, 409-415. (Pubitemid 35448669)
    • (2002) Journal of Clinical Neurophysiology , vol.19 , Issue.5 , pp. 409-415
    • Seyal, M.1    Mull, B.2
  • 25
    • 0026799286 scopus 로고
    • Study of experimental cervical spondylotic myelopathy
    • Shinomiya, K., Mutoh, N., and Furuya, K. (1992). Study of experimental cervical spondylotic myelopathy. Spine (Phila. Pa. 1976) 17, S383-S387.
    • (1992) Spine (Phila. Pa. 1976) , vol.17
    • Shinomiya, K.1    Mutoh, N.2    Furuya, K.3
  • 26
    • 0031761570 scopus 로고    scopus 로고
    • Histological investigation of spinal cord lesions in the spinal hyperostotic mouse (twy/twyl: Morphological changes in anterior horn cells and immunoreactivity to neurotropic factors
    • DOI 10.1007/s004150050287
    • Uchida, K., Baba, H., Maezawa, Y., Furukawa, S., Furusawa, N., and Imura, S. (1998). Histological investigation of spinal cord lesions in the spinal hyperostotic mouse (twy/twy): morphological changes in anterior horn cells and immunoreactivity to neurotropic factors. J. Neurol. 245, 781-793. (Pubitemid 28505273)
    • (1998) Journal of Neurology , vol.245 , Issue.12 , pp. 781-793
    • Uchida, K.1    Baba, H.2    Maezawa, Y.3    Furukawa, S.4    Furusawa, N.5    Imura, S.6
  • 28
    • 40949132429 scopus 로고    scopus 로고
    • Destructive pathological changes in the rat spinal cord due to chronic mechanical compression: Laboratory investigation
    • DOI 10.3171/SPI/2008/8/3/279
    • Xu, P., Gong, W.M., Li, Y., Zhang, T., Zhang, K., Yin, D.Z., and Jia, T.H. (2008). Destructive pathological changes in the rat spinal cord due to chronic mechanical compression. Laboratory investigation. J. Neurosurg. Spine 8, 279-285. (Pubitemid 351413956)
    • (2008) Journal of Neurosurgery: Spine , vol.8 , Issue.3 , pp. 279-285
    • Xu, P.1    Gong, W.-M.2    Li, Y.3    Zhang, T.4    Zhang, K.5    Yin, D.-Z.6    Jia, T.-H.7
  • 29
    • 0034283594 scopus 로고    scopus 로고
    • Cervical spondylotic myelopathy: A common cause of spinal cord dysfunction in older persons
    • 1073
    • Young, W.F. (2000). Cervical spondylotic myelopathy: a common cause of spinal cord dysfunction in older persons. Am. Fam. Physician 62, 1064-1070, 1073.
    • (2000) Am. Fam. Physician , vol.62 , pp. 1064-1070
    • Young, W.F.1
  • 30
    • 58249118699 scopus 로고    scopus 로고
    • Molecular mechanisms of spinal cord dysfunction and cell death in the spinal hyperostotic mouse: Implications for the pathophysiology of human cervical spondylotic myelopathy
    • Yu, W.R., Baptiste, D.C., Liu, T., Odrobina, E., Stanisz, G.J., and Fehlings, M.G. (2009). Molecular mechanisms of spinal cord dysfunction and cell death in the spinal hyperostotic mouse: implications for the pathophysiology of human cervical spondylotic myelopathy. Neurobiol. Dis. 33, 149-163.
    • (2009) Neurobiol. Dis. , vol.33 , pp. 149-163
    • Yu, W.R.1    Baptiste, D.C.2    Liu, T.3    Odrobina, E.4    Stanisz, G.J.5    Fehlings, M.G.6


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