Mechanism of the inhibitory effect of atorvastatin on leptin expression induced by angiotensin II in cultured human coronary artery smooth muscle cells

Clinical Science

Volumn 122, Issue 1, 2012, Pages 33-42

  Shyu, Kou Gi ^a,b   Chen, Shih Chung ^c,d   Wang, Bao Wei ^a   Cheng, Wen Pin ^a   Hung, Huei Fong ^a  

^a SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI CITY HOSPITAL   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Angiotensin II; Atherosclerosis; Leptin; Smooth muscle cell; Statin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ANGIOTENSIN II; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ATORVASTATIN; LEPTIN; MESSENGER RNA; MEVALONIC ACID; PHOSPHOPROTEIN; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; SEMICARBAZONE DERIVATIVE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; HEPTANOIC ACID DERIVATIVE; HYPOCHOLESTEROLEMIC AGENT; PYRROLE DERIVATIVE; RAC1 PROTEIN, HUMAN; VASOCONSTRICTOR AGENT;

ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY; DRUG MECHANISM; GENE ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; SMOOTH MUSCLE FIBER; CELL CULTURE; CELL MOTION; CORONARY BLOOD VESSEL; CYTOLOGY; DRUG EFFECT; GENETICS; METABOLISM; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANGIOTENSIN II; ANTICHOLESTEREMIC AGENTS; BLOTTING, WESTERN; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; CORONARY VESSELS; HEPTANOIC ACIDS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LEPTIN; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PYRROLES; RAC1 GTP-BINDING PROTEIN; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; VASOCONSTRICTOR AGENTS;

EID: 84863362682     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20110114     Document Type: Article

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