-
1
-
-
66149083275
-
Review of recent genome-wide association scans in lupus
-
Graham RR, Hom G, Ortmann W et al. Review of recent genome-wide association scans in lupus. J Intern Med 2009;265:680-8.
-
(2009)
J Intern Med
, vol.265
, pp. 680-688
-
-
Graham, R.R.1
Hom, G.2
Ortmann, W.3
-
2
-
-
77952888454
-
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
-
Stahl EA, Raychaudhuri S, Remmers EF et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet 2010; 42:508-14.
-
(2010)
Nat Genet
, vol.42
, pp. 508-514
-
-
Stahl, E.A.1
Raychaudhuri, S.2
Remmers, E.F.3
-
3
-
-
57749193136
-
Detecting shared pathogenesis from the shared genetics of immune-related diseases
-
Zhernakova A, van Diemen CC, Wijmenga C. Detecting shared pathogenesis from the shared genetics of immune-related diseases. Nat Rev Genet 2009;10:43-55.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 43-55
-
-
Zhernakova, A.1
van Diemen, C.C.2
Wijmenga, C.3
-
4
-
-
77952557918
-
Missing heritability and strategies for finding the underlying causes of complex disease
-
Eichler EE, Flint J, Gibson G et al. Missing heritability and strategies for finding the underlying causes of complex disease. Nat Rev Genet 2010;11:446-50.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 446-450
-
-
Eichler, E.E.1
Flint, J.2
Gibson, G.3
-
5
-
-
75149189005
-
Type I interferons: crucial participants in disease amplification in autoimmunity
-
Hall JC, Rosen A. Type I interferons: crucial participants in disease amplification in autoimmunity. Nat Rev Rheumatol 2010;6:40-9.
-
(2010)
Nat Rev Rheumatol
, vol.6
, pp. 40-49
-
-
Hall, J.C.1
Rosen, A.2
-
6
-
-
0842266786
-
Interferon-gamma: an overview of signals, mechanisms and functions
-
Schroder K, Hertzog PJ, Ravasi T et al. Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol 2004;75:163-89.
-
(2004)
J Leukoc Biol
, vol.75
, pp. 163-189
-
-
Schroder, K.1
Hertzog, P.J.2
Ravasi, T.3
-
7
-
-
0344492212
-
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
-
Baechler EC, Batliwalla FM, Karypis G et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc Natl Acad Sci USA 2003;100:2610-5.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 2610-2615
-
-
Baechler, E.C.1
Batliwalla, F.M.2
Karypis, G.3
-
8
-
-
0030022275
-
The role of interleukin-15 in T-cell migration and activation in rheumatoid arthritis
-
McInnes IB, al-Mughales J, Field M et al. The role of interleukin-15 in T-cell migration and activation in rheumatoid arthritis. Nat Med 1996;2:175-82.
-
(1996)
Nat Med
, vol.2
, pp. 175-182
-
-
McInnes, I.B.1
al-Mughales, J.2
Field, M.3
-
9
-
-
0036163273
-
Interferon-gamma:interleukin 4 ratios and associated type 1 cytokine expression in juvenile rheumatoid arthritis synovial tissue
-
Scola MP, Thompson SD, Brunner HI et al. Interferon-gamma:interleukin 4 ratios and associated type 1 cytokine expression in juvenile rheumatoid arthritis synovial tissue. J Rheumatol 2002;29: 369-78.
-
(2002)
J Rheumatol
, vol.29
, pp. 369-378
-
-
Scola, M.P.1
Thompson, S.D.2
Brunner, H.I.3
-
10
-
-
0031156936
-
Accelerated collagen-induced arthritis in IFN-gamma receptordeficient mice
-
Vermeire K, Heremans H, Vandeputte M et al. Accelerated collagen-induced arthritis in IFN-gamma receptordeficient mice. J Immunol 1997;158:5507-13.
-
(1997)
J Immunol
, vol.158
, pp. 5507-5513
-
-
Vermeire, K.1
Heremans, H.2
Vandeputte, M.3
-
11
-
-
0032103993
-
Soluble IL-15 receptor alpha-chain administration prevents murine collageninduced arthritis: a role for IL-15 in development of antigen-induced immunopathology
-
Ruchatz H, Leung BP, Wei XQ et al. Soluble IL-15 receptor alpha-chain administration prevents murine collageninduced arthritis: a role for IL-15 in development of antigen-induced immunopathology. J Immunol 1998;160: 5654-60.
-
(1998)
J Immunol
, vol.160
, pp. 5654-5660
-
-
Ruchatz, H.1
Leung, B.P.2
Wei, X.Q.3
-
12
-
-
13844292408
-
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
-
Sigurdsson S, Nordmark G, Goring HH et al. Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet 2005;76: 528-37.
-
(2005)
Am J Hum Genet
, vol.76
, pp. 528-537
-
-
Sigurdsson, S.1
Nordmark, G.2
Goring, H.H.3
-
13
-
-
13244277850
-
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
-
Prokunina L, Castillejo-Lopez C, Oberg F et al. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nat Genet 2002;32:666-9.
-
(2002)
Nat Genet
, vol.32
, pp. 666-669
-
-
Prokunina, L.1
Castillejo-Lopez, C.2
Oberg, F.3
-
14
-
-
2642575164
-
Association of the PD-1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope
-
Prokunina L, Padyukov L, Bennet A et al. Association of the PD-1.3A allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope. Arthritis Rheum 2004;50: 1770-3.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1770-1773
-
-
Prokunina, L.1
Padyukov, L.2
Bennet, A.3
-
15
-
-
34547492359
-
Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis
-
Sigurdsson S, Padyukov L, Kurreeman FA et al. Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis. Arthritis Rheum 2007;56:2202-10.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2202-2210
-
-
Sigurdsson, S.1
Padyukov, L.2
Kurreeman, F.A.3
-
16
-
-
79959828831
-
Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus (SLE)
-
Ramos PS, Williams AH, Ziegler JT et al. Genetic analyses of interferon pathway-related genes reveal multiple new loci associated with systemic lupus erythematosus (SLE). Arthritis Rheum 2011;63:2049-57.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 2049-2057
-
-
Ramos, P.S.1
Williams, A.H.2
Ziegler, J.T.3
-
17
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31:315-24.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
-
18
-
-
0020436689
-
The 1982 revised criteria for the classification of systemic lupus erythematosus
-
Tan EM, Cohen AS, Fries JF et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7.
-
(1982)
Arthritis Rheum
, vol.25
, pp. 1271-1277
-
-
Tan, E.M.1
Cohen, A.S.2
Fries, J.F.3
-
19
-
-
10744230484
-
International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001
-
Petty RE, Southwood TR, Manners P et al. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001. J Rheumatol 2004;31:390-2.
-
(2004)
J Rheumatol
, vol.31
, pp. 390-392
-
-
Petty, R.E.1
Southwood, T.R.2
Manners, P.3
-
20
-
-
77951731231
-
Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in four European populations
-
van der WD, Lie BA, Lundstrom E et al. Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in four European populations. Arthritis Rheum 2010;62:1236-45.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1236-1245
-
-
van der, W.D.1
Lie, B.A.2
Lundstrom, E.3
-
21
-
-
2442551586
-
A multicenter international evaluation of single-tube amplification protocols for sequencing-based typing of HLA-DRB1 and HLA-DRB3,4, 5
-
Sayer DC, Whidborne R, De SD et al. A multicenter international evaluation of single-tube amplification protocols for sequencing-based typing of HLA-DRB1 and HLA-DRB3,4,5. Tissue Antigens 2004;63:412-23.
-
(2004)
Tissue Antigens
, vol.63
, pp. 412-423
-
-
Sayer, D.C.1
Whidborne, R.2
De, S.D.3
-
22
-
-
34548492784
-
Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis
-
Viken MK, Sollid HD, Joner G et al. Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis. Hum Immunol 2007;68:748-55.
-
(2007)
Hum Immunol
, vol.68
, pp. 748-755
-
-
Viken, M.K.1
Sollid, H.D.2
Joner, G.3
-
23
-
-
33646368404
-
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
-
Graham RR, Kozyrev SV, Baechler EC et al. A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nat Genet 2006;38: 550-5.
-
(2006)
Nat Genet
, vol.38
, pp. 550-555
-
-
Graham, R.R.1
Kozyrev, S.V.2
Baechler, E.C.3
-
24
-
-
34247254495
-
Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus
-
Kozyrev SV, Lewen S, Reddy PM et al. Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus. Arthritis Rheum 2007;56:1234-41.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1234-1241
-
-
Kozyrev, S.V.1
Lewen, S.2
Reddy, P.M.3
-
25
-
-
34548292504
-
PLINK: a tool set for whole-genome association and populationbased linkage analyses
-
Purcell S, Neale B, Todd-Brown K et al. PLINK: a tool set for whole-genome association and populationbased linkage analyses. Am J Hum Genet 2007;81: 559-75.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
-
26
-
-
41649094148
-
Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
-
Dudbridge F. Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Hum Hered 2008;66:87-98.
-
(2008)
Hum Hered
, vol.66
, pp. 87-98
-
-
Dudbridge, F.1
-
27
-
-
0025215247
-
Power and sample size calculations. A review and computer program
-
Dupont WD, Plummer WD Jr. Power and sample size calculations. A review and computer program. Control Clin Trials 1990;11:116-28.
-
(1990)
Control Clin Trials
, vol.11
, pp. 116-128
-
-
Dupont, W.D.1
Plummer Jr., W.D.2
-
28
-
-
43949086215
-
Association of interferon regulatory factor 5 haplotypes, similar to that found in systemic lupus erythematosus, in a large subgroup of patients with rheumatoid arthritis
-
eguez-Gonzalez R, Calaza M, Perez-Pampin E et al. Association of interferon regulatory factor 5 haplotypes, similar to that found in systemic lupus erythematosus, in a large subgroup of patients with rheumatoid arthritis. Arthritis Rheum 2008;58:1264-74.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1264-1274
-
-
eguez-Gonzalez, R.1
Calaza, M.2
Perez-Pampin, E.3
-
29
-
-
40649121122
-
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus
-
Sigurdsson S, Goring HH, Kristjansdottir G et al. Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus. Hum Mol Genet 2008;17: 872-81.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 872-881
-
-
Sigurdsson, S.1
Goring, H.H.2
Kristjansdottir, G.3
-
30
-
-
75749153301
-
Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus
-
Feng D, Stone RC, Eloranta ML et al. Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus. Arthritis Rheum 2010;62:562-73.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 562-573
-
-
Feng, D.1
Stone, R.C.2
Eloranta, M.L.3
-
31
-
-
77949732090
-
Promoter insertion/deletion in the IRF5 gene is highly associated with susceptibility to systemic lupus erythematosus in distinct populations, but exerts a modest effect on gene expression in peripheral blood mononuclear cells
-
Lofgren SE, Yin H, gado-Vega AM et al. Promoter insertion/deletion in the IRF5 gene is highly associated with susceptibility to systemic lupus erythematosus in distinct populations, but exerts a modest effect on gene expression in peripheral blood mononuclear cells. J Rheumatol 2010;37:574-8.
-
(2010)
J Rheumatol
, vol.37
, pp. 574-578
-
-
Lofgren, S.E.1
Yin, H.2
gado-Vega, A.M.3
-
32
-
-
33646370647
-
TNF downmodulates the function of human CD4+CD25hi T-regulatory cells
-
Valencia X, Stephens G, Goldbach-Mansky R et al. TNF downmodulates the function of human CD4+CD25hi T-regulatory cells. Blood 2006;108:253-61.
-
(2006)
Blood
, vol.108
, pp. 253-261
-
-
Valencia, X.1
Stephens, G.2
Goldbach-Mansky, R.3
-
33
-
-
0035900481
-
Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus
-
Blanco P, Palucka AK, Gill M et al. Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. Science 2001;294:1540-3.
-
(2001)
Science
, vol.294
, pp. 1540-1543
-
-
Blanco, P.1
Palucka, A.K.2
Gill, M.3
-
34
-
-
34247162727
-
Association of a common interferon regulatory factor 5 (IRF5) variant with increased risk of systemic lupus erythematosus (SLE)
-
Demirci FY, Manzi S, Ramsey-Goldman R et al. Association of a common interferon regulatory factor 5 (IRF5) variant with increased risk of systemic lupus erythematosus (SLE). Ann Hum Genet 2007;71: 308-11.
-
(2007)
Ann Hum Genet
, vol.71
, pp. 308-311
-
-
Demirci, F.Y.1
Manzi, S.2
Ramsey-Goldman, R.3
-
35
-
-
34547541897
-
Opposed independent effects and epistasis in the complex association of IRF5 to SLE
-
Ferreiro-Neira I, Calaza M, onso-Perez E et al. Opposed independent effects and epistasis in the complex association of IRF5 to SLE. Genes Immun 2007;8:429-38.
-
(2007)
Genes Immun
, vol.8
, pp. 429-438
-
-
Ferreiro-Neira, I.1
Calaza, M.2
onso-Perez, E.3
-
36
-
-
79953301748
-
Association of IRF5 polymorphisms with susceptibility to macrophage activation syndrome in patients with juvenile idiopathic arthritis
-
Yanagimachi M, Naruto T, Miyamae T et al. Association of IRF5 polymorphisms with susceptibility to macrophage activation syndrome in patients with juvenile idiopathic arthritis. J Rheumatol 2011;38:769-74.
-
(2011)
J Rheumatol
, vol.38
, pp. 769-774
-
-
Yanagimachi, M.1
Naruto, T.2
Miyamae, T.3
-
37
-
-
33845623329
-
Analysis of IRF5 gene functional polymorphisms in rheumatoid arthritis
-
Rueda B, Reddy MV, Gonzalez-Gay MA et al. Analysis of IRF5 gene functional polymorphisms in rheumatoid arthritis. Arthritis Rheum 2006;54:3815-9.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3815-3819
-
-
Rueda, B.1
Reddy, M.V.2
Gonzalez-Gay, M.A.3
-
38
-
-
34249815199
-
IRF5 rs2004640-T allele, the new genetic factor for systemic lupus erythematosus, is not associated with rheumatoid arthritis
-
Garnier S, Dieude P, Michou L et al. IRF5 rs2004640-T allele, the new genetic factor for systemic lupus erythematosus, is not associated with rheumatoid arthritis. Ann Rheum Dis 2007;66:828-31.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 828-831
-
-
Garnier, S.1
Dieude, P.2
Michou, L.3
-
39
-
-
58249123282
-
Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis
-
Dieude P, Guedj M, Wipff J et al. Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis. Arthritis Rheum 2009;60:225-33.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 225-233
-
-
Dieude, P.1
Guedj, M.2
Wipff, J.3
-
40
-
-
59149104204
-
Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjogren's syndrome
-
Nordmark G, Kristjansdottir G, Theander E et al. Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjogren's syndrome. Genes Immun 2009;10: 68-76.
-
(2009)
Genes Immun
, vol.10
, pp. 68-76
-
-
Nordmark, G.1
Kristjansdottir, G.2
Theander, E.3
-
41
-
-
45249112573
-
Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations
-
Kristjansdottir G, Sandling JK, Bonetti A et al. Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations. J Med Genet 2008;45:362-9.
-
(2008)
J Med Genet
, vol.45
, pp. 362-369
-
-
Kristjansdottir, G.1
Sandling, J.K.2
Bonetti, A.3
-
42
-
-
36249002287
-
An insertion-deletion polymorphism in the interferon regulatory factor 5 (IRF5) gene confers risk of inflammatory bowel diseases
-
Dideberg V, Kristjansdottir G, Milani L et al. An insertion-deletion polymorphism in the interferon regulatory factor 5 (IRF5) gene confers risk of inflammatory bowel diseases. Hum Mol Genet 2007;16: 3008-16.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 3008-3016
-
-
Dideberg, V.1
Kristjansdottir, G.2
Milani, L.3
-
43
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
Anderson CA, Boucher G, Lees CW et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet 2011;43:246-52.
-
(2011)
Nat Genet
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
-
44
-
-
0030175721
-
Imprinted and genotype-specific expression of genes at the IDDM2 locus in pancreas and leucocytes
-
Vafiadis P, Bennett ST, Colle E et al. Imprinted and genotype-specific expression of genes at the IDDM2 locus in pancreas and leucocytes. J Autoimmun 1996;9: 397-403.
-
(1996)
J Autoimmun
, vol.9
, pp. 397-403
-
-
Vafiadis, P.1
Bennett, S.T.2
Colle, E.3
-
45
-
-
18244421874
-
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
-
Pugliese A, Zeller M, Fernandez A Jr et al. The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. Nat Genet 1997;15:293-7.
-
(1997)
Nat Genet
, vol.15
, pp. 293-297
-
-
Pugliese, A.1
Zeller, M.2
Fernandez Jr., A.3
-
46
-
-
50449111452
-
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
-
Graham RR, Cotsapas C, Davies L et al. Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet 2008;40: 1059-61.
-
(2008)
Nat Genet
, vol.40
, pp. 1059-1061
-
-
Graham, R.R.1
Cotsapas, C.2
Davies, L.3
-
47
-
-
50449103533
-
Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus
-
Musone SL, Taylor KE, Lu TT et al. Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus. Nat Genet 2008;40:1062-4.
-
(2008)
Nat Genet
, vol.40
, pp. 1062-1064
-
-
Musone, S.L.1
Taylor, K.E.2
Lu, T.T.3
|