Promoter insertion/deletion in the IRF5 gene is highly associated with susceptibility to systemic lupus erythematosus in distinct populations, but exerts a modest effect on gene expression in peripheral blood mononuclear cells

Journal of Rheumatology

Volumn 37, Issue 3, 2010, Pages 574-577

  Löfgren, Sara E ^a   Yin, Hong ^a   Delgado Vega, Angelica M ^a   Sanchez, Elena ^a   Lewén, Susanna ^a   Pons Estel, Bernardo A ^a,b   Witte, Torsten ^a,c   D'Alfonso, Sandra ^a,d   Ortego Centeno, Norberto ^a   Martin, Javier ^a,e   Alarcón Riquelme, Marta E ^a   Kozyrev, Sergey V ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b Sanatorio Parque   (Argentina)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^e INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

Author keywords

Gene expression; Interferon regulatory factor 5; Systemic lupus erythematosus

Indexed keywords

ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; GENE; GENE AMPLIFICATION; GENE DELETION; GENE EXPRESSION; GENE INSERTION; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HUMAN; INDEL MUTATION; IRF5 GENE; MAJOR CLINICAL STUDY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS;

ARGENTINA; CASE-CONTROL STUDIES; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GERMANY; HUMANS; INDEL MUTATION; INTERFERON REGULATORY FACTORS; ITALY; LEUKOCYTES, MONONUCLEAR; LUPUS ERYTHEMATOSUS, SYSTEMIC; MEXICO; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; SPAIN;

EID: 77949732090     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: 10.3899/jrheum.090440     Document Type: Article

References (17)

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