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Volumn 176, Issue 1, 2012, Pages 70-79

Strategies for genetic association analyses combining unrelated case-control individuals and family trios

Author keywords

Alleles; Case control studies; Family trios; Genetic; Genetic association studies; Genetics; Odds ratio; Polymorphism; Risk

Indexed keywords

ALLELE; BLOOD SYSTEM DISORDER; CANCER; DISEASE INCIDENCE; DISEASE PREVALENCE; FAMILY STRUCTURE; GENETIC ANALYSIS; GENETIC STRUCTURE; HEALTH RISK; POLYMORPHISM; RISK FACTOR;

EID: 84863317393     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwr494     Document Type: Article
Times cited : (10)

References (28)
  • 1
    • 0036277684 scopus 로고    scopus 로고
    • Point: Population stratification: A problem for case-control studies of candidate-gene associations?
    • Thomas DC, Witte JS. Point: population stratification: a problem for case-control studies of candidate-gene associations? Cancer Epidemiol Biomarkers Prev. 2002;11(6):502-512.
    • (2002) Cancer Epidemiol Biomarkers Prev. , vol.11 , Issue.6 , pp. 502-512
    • Thomas, D.C.1    Witte, J.S.2
  • 4
    • 11244279011 scopus 로고    scopus 로고
    • An Icelandic example of the impact of population structure on association studies
    • DOI 10.1038/ng1492
    • Helgason A, Yngvadóttir B, Hrafnkelsson B, et al. An Icelandic example of the impact of population structure on association studies. Nat Genet. 2005;37(1):90-95. (Pubitemid 40070945)
    • (2005) Nature Genetics , vol.37 , Issue.1 , pp. 90-95
    • Helgason, A.1    Yngvadottir, B.2    Hrafnkelsson, B.3    Gulcher, J.4    Stefansson, K.5
  • 5
    • 0032714352 scopus 로고    scopus 로고
    • Genomic control for association studies
    • Devlin B, Roeder K. Genomic control for association studies. Biometrics. 1999;55(4):997-1004.
    • (1999) Biometrics. , vol.55 , Issue.4 , pp. 997-1004
    • Devlin, B.1    Roeder, K.2
  • 6
    • 0034118493 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data
    • Pritchard JK, Stephens M, Donnelly P. Inference of population structure using multilocus genotype data. Genetics. 2000;155(2):945-959. (Pubitemid 30397141)
    • (2000) Genetics , vol.155 , Issue.2 , pp. 945-959
    • Pritchard, J.K.1    Stephens, M.2    Donnelly, P.3
  • 8
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • DOI 10.1038/ng1847, PII NG1847
    • Price AL, Patterson NJ, Plenge RM, et al. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet. 2006;38(8):904-909. (Pubitemid 44141658)
    • (2006) Nature Genetics , vol.38 , Issue.8 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5    Reich, D.6
  • 9
    • 0036094264 scopus 로고    scopus 로고
    • Power and efficiency of the TDT and case-control design for association scans
    • DOI 10.1023/A:1015205924326
    • McGinnis R, Shifman S, Darvasi A. Power and efficiency of the TDT and case-control design for association scans. Behav Genet. 2002;32(2):135-144. (Pubitemid 34522422)
    • (2002) Behavior Genetics , vol.32 , Issue.2 , pp. 135-144
    • McGinnis, R.1    Shifman, S.2    Darvasi, A.3
  • 10
    • 33646188852 scopus 로고    scopus 로고
    • Family-based designs in the age of large-scale gene-association studies
    • Laird NM, Lange C. Family-based designs in the age of large-scale gene-association studies. Nat Rev Genet. 2006;7(5):385-394.
    • (2006) Nat Rev Genet. , vol.7 , Issue.5 , pp. 385-394
    • Laird, N.M.1    Lange, C.2
  • 11
    • 0033913218 scopus 로고    scopus 로고
    • Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions
    • DOI 10.1086/302782
    • Lunetta KL, Faraone SV, Biederman J, et al. Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions. Am J Hum Genet. 2000;66(2):605-614. (Pubitemid 30468838)
    • (2000) American Journal of Human Genetics , vol.66 , Issue.2 , pp. 605-614
    • Lunetta, K.L.1    Faraone, S.V.2    Biederman, J.3    Laird, N.M.4
  • 12
    • 0035706151 scopus 로고    scopus 로고
    • The power of the transmission disequilibrium test (TDT) with both case-parent and control-parent trios
    • Deng HW, Chen WM. The power of the transmission disequilibrium test (TDT) with both case-parent and control-parent trios. Genet Res. 2001;78(3):289-302.
    • (2001) Genet Res. , vol.78 , Issue.3 , pp. 289-302
    • Deng, H.W.1    Chen, W.M.2
  • 13
    • 0029858544 scopus 로고    scopus 로고
    • The TDT and other family-based tests for linkage disequilibrium and association
    • Spielman RS, Ewens WJ. The TDT and other family-based tests for linkage disequilibrium and association. Am J Hum Genet. 1996;59(5):983-989. (Pubitemid 26346336)
    • (1996) American Journal of Human Genetics , vol.59 , Issue.5 , pp. 983-989
    • Spielman, R.S.1    Ewens, W.J.2
  • 14
    • 70249086596 scopus 로고    scopus 로고
    • Combining case-control and case-trio data from the same population in genetic association analyses: Overview of approaches and illustration with a candidate gene study
    • Infante-Rivard C, Mirea L, Bull SB. Combining case-control and case-trio data from the same population in genetic association analyses: overview of approaches and illustration with a candidate gene study. Am J Epidemiol. 2009;170(5):657-664.
    • (2009) Am J Epidemiol. , vol.170 , Issue.5 , pp. 657-664
    • Infante-Rivard, C.1    Mirea, L.2    Bull, S.B.3
  • 15
    • 64149098543 scopus 로고    scopus 로고
    • Comparison of methods for combining case-control and family-based association studies
    • Glaser B, Holmans P. Comparison of methods for combining case-control and family-based association studies. Hum Hered. 2009;68(2):106-116.
    • (2009) Hum Hered. , vol.68 , Issue.2 , pp. 106-116
    • Glaser, B.1    Holmans, P.2
  • 16
    • 0033909546 scopus 로고    scopus 로고
    • A general test of association for quantitative traits in nuclear families
    • DOI 10.1086/302698
    • Abecasis GR, Cardon LR, Cookson WO. A general test of association for quantitative traits in nuclear families. Am J Hum Genet. 2000;66(1):279-292. (Pubitemid 30481489)
    • (2000) American Journal of Human Genetics , vol.66 , Issue.1 , pp. 279-292
    • Abecasis, G.R.1    Cardon, L.R.2    Cookson, W.O.C.3
  • 17
    • 77954182347 scopus 로고    scopus 로고
    • Using evidence for population stratification bias in combined individual- And family-level genetic association analyses of quantitative traits
    • Mirea L, Sun L, Stafford JE, et al. Using evidence for population stratification bias in combined individual- and family-level genetic association analyses of quantitative traits. Genet Epidemiol. 2010;34(5):502-511.
    • (2010) Genet Epidemiol. , vol.34 , Issue.5 , pp. 502-511
    • Mirea, L.1    Sun, L.2    Stafford, J.E.3
  • 18
    • 51749116889 scopus 로고    scopus 로고
    • Simple association analysis combining data from trios/sibships and unrelated controls
    • Chen YH, Lin HW. Simple association analysis combining data from trios/sibships and unrelated controls. Genet Epidemiol. 2008;32(6):520-527.
    • (2008) Genet Epidemiol. , vol.32 , Issue.6 , pp. 520-527
    • Chen, Y.H.1    Lin, H.W.2
  • 19
    • 0025903577 scopus 로고
    • On estimating HLA/disease association with application to a study of aplastic anemia
    • Self SG, Longton G, Kopecky KJ, et al. On estimating HLA/disease association with application to a study of aplastic anemia. Biometrics. 1991;47(1):53-61.
    • (1991) Biometrics. , vol.47 , Issue.1 , pp. 53-61
    • Self, S.G.1    Longton, G.2    Kopecky, K.J.3
  • 20
    • 0027367005 scopus 로고
    • Genotype relative risks: Methods for design and analysis of candidate- Gene association studies
    • Schaid DJ, Sommer SS. Genotype relative risks: methods for design and analysis of candidate-gene association studies. Am J Hum Genet. 1993;53(5):1114-1126. (Pubitemid 23313776)
    • (1993) American Journal of Human Genetics , vol.53 , Issue.5 , pp. 1114-1126
    • Schaid, D.J.1    Sommer, S.S.2
  • 21
    • 35748932852 scopus 로고    scopus 로고
    • R Development Core Team. Vienna, Austria: R Foundation for Statistical Computing; (Accessed May 31, 2011)
    • R Development Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing; 2007. (http://www.R-project.org). (Accessed May 31, 2011).
    • (2007) R: A Language and Environment for Statistical Computing
  • 22
    • 34447272901 scopus 로고    scopus 로고
    • Excess transmission of the NAD(P)H:quinone oxidoreductase 1 (NQO1) C609T polymorphism in families of children with acute lymphoblastic leukemia
    • DOI 10.1093/aje/kwm022
    • Infante-Rivard C, Vermunt JK, Weinberg CR. Excess transmission of the NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism in families of children with acute lymphoblastic leukemia. Am J Epidemiol. 2007;165(11):1248- 1254. (Pubitemid 47234330)
    • (2007) American Journal of Epidemiology , vol.165 , Issue.11 , pp. 1248-1254
    • Infante-Rivard, C.1    Vermunt, J.K.2    Weinberg, C.R.3
  • 23
    • 70450190156 scopus 로고    scopus 로고
    • Canadian Cancer Society/National Cancer Institute of Canada. Toronto, Ontario, Canada: Canadian Cancer Society
    • Canadian Cancer Society/National Cancer Institute of Canada. Canadian Cancer Statistics 2008. Toronto, Ontario, Canada: Canadian Cancer Society; 2008.
    • (2008) Canadian Cancer Statistics 2008
  • 24
    • 12344261638 scopus 로고    scopus 로고
    • Parental phenotypes in family based association analysis
    • DOI 10.1086/427886
    • Purcell S, Sham P, Daly MJ. Parental phenotypes in family-based association analysis. Am J Hum Genet. 2005;76(2):249-259. (Pubitemid 40129551)
    • (2005) American Journal of Human Genetics , vol.76 , Issue.2 , pp. 249-259
    • Purcell, S.1    Sham, P.2    Daly, M.J.3
  • 26
    • 41649094148 scopus 로고    scopus 로고
    • Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
    • DOI 10.1159/000119108
    • Dudbridge F. Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Hum Hered. 2008;66(2):87-98. (Pubitemid 351482562)
    • (2008) Human Heredity , vol.66 , Issue.2 , pp. 87-98
    • Dudbridge, F.1
  • 27
    • 77950460630 scopus 로고    scopus 로고
    • On genome-wide association studies for family-based designs: An integrative analysis approach combining ascertained family samples with unselected controls
    • Lasky-Su J, Won S, Mick E, et al. On genome-wide association studies for family-based designs: an integrative analysis approach combining ascertained family samples with unselected controls. Am J Hum Genet. 2010;86(4):573-580.
    • (2010) Am J Hum Genet. , vol.86 , Issue.4 , pp. 573-580
    • Lasky-Su, J.1    Won, S.2    Mick, E.3
  • 28
    • 40749128980 scopus 로고    scopus 로고
    • A Unified Association Analysis Approach for Family and Unrelated Samples Correcting for Stratification
    • DOI 10.1016/j.ajhg.2007.10.009, PII S0002929708000876
    • Zhu X, Li S, Cooper RS, et al. A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet. 2008;82(2):352-365. (Pubitemid 351726103)
    • (2008) American Journal of Human Genetics , vol.82 , Issue.2 , pp. 352-365
    • Zhu, X.1    Li, S.2    Cooper, R.S.3    Elston, R.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.