-
1
-
-
0026508487
-
Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5′ and the 6th phosphodiester bond 3′ to the photodimer
-
Huang, J. C., Svoboda, D. L., Reardon, J. T., and Sancar, A. (1992) Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5′ and the 6th phosphodiester bond 3′ to the photodimer. Proc. Natl. Acad. Sci. U.S.A. 89, 3664-3668
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 3664-3668
-
-
Huang, J.C.1
Svoboda, D.L.2
Reardon, J.T.3
Sancar, A.4
-
2
-
-
0028242355
-
Determination of minimum substrate size for human excinuclease
-
Huang, J. C., and Sancar, A. (1994) Determination of minimum substrate size for human excinuclease. J. Biol. Chem. 269, 19034-19040
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 19034-19040
-
-
Huang, J.C.1
Sancar, A.2
-
3
-
-
0027392108
-
DNA repair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes
-
Svoboda, D. L., Taylor, J. S., Hearst, J. E., and Sancar, A. (1993)DNArepair by eukaryotic nucleotide excision nuclease. Removal of thymine dimer and psoralen monoadduct by HeLa cell-free extract and of thymine dimer by Xenopus laevis oocytes. J. Biol. Chem. 268, 1931-1936 (Pubitemid 23033595)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.3
, pp. 1931-1936
-
-
Svoboda, D.L.1
Taylor, J.-S.2
Hearst, J.E.3
Sancar, A.4
-
4
-
-
82455218968
-
BRCA1 is required for postreplication repair after UV-induced DNA damage
-
Pathania, S., Nguyen, J., Hill, S. J., Scully, R., Adelmant, G. O., Marto, J. A., Feunteun, J., and Livingston, D. M. (2011) BRCA1 is required for postreplication repair after UV-induced DNA damage. Mol. Cell 44, 235-251
-
(2011)
Mol. Cell
, vol.44
, pp. 235-251
-
-
Pathania, S.1
Nguyen, J.2
Hill, S.J.3
Scully, R.4
Adelmant, G.O.5
Marto, J.A.6
Feunteun, J.7
Livingston, D.M.8
-
5
-
-
0030855076
-
Rodent UV-sensitive mutant cell lines in complementation groups 6-10 have normal general excision repair activity
-
DOI 10.1093/nar/25.5.1015
-
Reardon, J. T., Thompson, L. H., and Sancar, A. (1997) Rodent UV-sensitive mutant cell lines in complementation groups 6-10 have normal general excision repair activity. Nucleic Acids Res. 25, 1015-1021 (Pubitemid 27298271)
-
(1997)
Nucleic Acids Research
, vol.25
, Issue.5
, pp. 1015-1021
-
-
Reardon, J.T.1
Thompson, L.H.2
Sancar, A.3
-
6
-
-
0018844455
-
DNA repair in human cells containing photoadducts of 8-methoxypsoralen or angelicin
-
Kaye, J., Smith, C. A., and Hanawalt, P. C. (1980) DNA repair in human cells containing photoadducts of 8-methoxypsoralen or angelicin. Cancer Res. 40, 696-702 (Pubitemid 10174891)
-
(1980)
Cancer Research
, vol.40
, Issue.3
, pp. 696-702
-
-
Kaye, J.1
Smith, C.A.2
Hanawalt, P.C.3
-
7
-
-
0026213471
-
Cyclobutane dimers and (6-4) photoproducts in human cells are mended with the same patch sizes
-
Cleaver, J. E., Jen, J., Charles, W. C., and Mitchell, D. L. (1991) Cyclobutane dimers and (6-4) photoproducts in human cells are mended with the same patch sizes. Photochem. Photobiol. 54, 393-402
-
(1991)
Photochem. Photobiol.
, vol.54
, pp. 393-402
-
-
Cleaver, J.E.1
Jen, J.2
Charles, W.C.3
Mitchell, D.L.4
-
8
-
-
0028896837
-
Reconstitution of human DNA repair excision nuclease in a highly defined system
-
Mu, D., Park, C. H., Matsunaga, T., Hsu, D. S., Reardon, J. T., and Sancar, A. (1995) Reconstitution of human DNA repair excision nuclease in a highly defined system. J. Biol. Chem. 270, 2415-2418
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2415-2418
-
-
Mu, D.1
Park, C.H.2
Matsunaga, T.3
Hsu, D.S.4
Reardon, J.T.5
Sancar, A.6
-
9
-
-
0029870677
-
Reaction mechanism of human DNA repair excision nuclease
-
DOI 10.1074/jbc.271.14.8285
-
Mu, D., Hsu, D. S., and Sancar, A. (1996) Reaction mechanism of human DNA repair excision nuclease. J. Biol. Chem. 271, 8285-8294 (Pubitemid 26108661)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.14
, pp. 8285-8294
-
-
Mu, D.1
Hsu, D.S.2
Sancar, A.3
-
10
-
-
0030732132
-
Mechanism of open complex and dual incision formation by human nucleotide excision repair factors
-
DOI 10.1093/emboj/16.21.6559
-
Evans, E., Moggs, J. G., Hwang, J. R., Egly, J. M., and Wood, R. D. (1997) Mechanism of open complex and dual incision formation by human nucleotide excision repair factors. EMBO J. 16, 6559-6573 (Pubitemid 27483280)
-
(1997)
EMBO Journal
, vol.16
, Issue.21
, pp. 6559-6573
-
-
Evans, E.1
Moggs, J.G.2
Hwang, J.R.3
Egly, J.-M.4
Wood, R.D.5
-
11
-
-
0029892790
-
DNA excision repair
-
Sancar, A. (1996) DNA excision repair. Annu. Rev. Biochem. 65, 43-81
-
(1996)
Annu. Rev. Biochem.
, vol.65
, pp. 43-81
-
-
Sancar, A.1
-
12
-
-
0030768038
-
Nucleotide excision repair in mammalian cells
-
Wood, R. D. (1997) Nucleotide excision repair in mammalian cells. J. Biol. Chem. 272, 23465-23468
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23465-23468
-
-
Wood, R.D.1
-
14
-
-
79960377998
-
XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase
-
Fuss, J. O., and Tainer, J. A. (2011) XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase. DNA Repair 10, 697-713
-
(2011)
DNA Repair
, vol.10
, pp. 697-713
-
-
Fuss, J.O.1
Tainer, J.A.2
-
16
-
-
0034939627
-
Mutation of DNASE1 in people with systemic lupus erythematosus
-
DOI 10.1038/91070
-
Yasutomo, K., Horiuchi, T., Kagami, S., Tsukamoto, H., Hashimura, C., Urushihara, M., and Kuroda, Y. (2001) Mutation of DNASE1 in people with systemic lupus erythematosus. Nat. Genet. 28, 313-314 (Pubitemid 32702418)
-
(2001)
Nature Genetics
, vol.28
, Issue.4
, pp. 313-314
-
-
Yasutomo, K.1
Horiuchi, T.2
Kagami, S.3
Tsukamoto, H.4
Hashimura, C.5
Urushihara, M.6
Kuroda, Y.7
-
17
-
-
49549100511
-
Trex1 prevents cell-intrinsic initiation of autoimmunity
-
Stetson, D. B., Ko, J. S., Heidmann, T., and Medzhitov, R. (2008) Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell. 134, 587-598
-
(2008)
Cell.
, vol.134
, pp. 587-598
-
-
Stetson, D.B.1
Ko, J.S.2
Heidmann, T.3
Medzhitov, R.4
-
18
-
-
80052752626
-
Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome
-
Fye, J. M., Orebaugh, C. D., Coffin, S. R., Hollis, T., and Perrino, F. W. (2011) Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome. J. Biol. Chem. 286, 32373-32382
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 32373-32382
-
-
Fye, J.M.1
Orebaugh, C.D.2
Coffin, S.R.3
Hollis, T.4
Perrino, F.W.5
-
19
-
-
0034114882
-
Features of systemic lupus erythematosus in Dnase1-deficient mice
-
DOI 10.1038/76032
-
Napirei, M., Karsunky, H., Zevnik, B., Stephan, H., Mannherz, H. G., and Möröy, T. (2000) Features of systemic lupus erythematosus in DNase1-deficient mice. Nat. Genet. 25, 177-181 (Pubitemid 30394988)
-
(2000)
Nature Genetics
, vol.25
, Issue.2
, pp. 177-181
-
-
Napirei, M.1
Karsunky, H.2
Zevnik, B.3
Stephan, H.4
Mannherz, H.G.5
Moroy, T.6
-
20
-
-
33645211068
-
Purification and characterization of Escherichia coli and human nucleotide excision repair enzyme systems
-
Reardon, J. T., and Sancar, A. (2006) Purification and characterization of Escherichia coli and human nucleotide excision repair enzyme systems. Methods Enzymol. 408, 189-213
-
(2006)
Methods Enzymol.
, vol.408
, pp. 189-213
-
-
Reardon, J.T.1
Sancar, A.2
-
21
-
-
0028245269
-
Recombinant replication protein A: Expression, complex formation, and functional characterization
-
Henricksen, L. A., Umbricht, C. B., and Wold, M. S. (1994) Recombinant replication protein A. Expression, complex formation, and functional characterization. J. Biol. Chem. 269, 11121-11132 (Pubitemid 24200317)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.15
, pp. 11121-11132
-
-
Henricksen, L.A.1
Umbricht, C.B.2
Wold, M.S.3
-
22
-
-
33745225420
-
Functional assays for replication protein A (RPA)
-
Binz, S. K., Dickson, A. M., Haring, S. J., and Wold, M. S. (2006) Functional assays for replication protein A (RPA). Methods Enzymol. 409, 11-38
-
(2006)
Methods Enzymol.
, vol.409
, pp. 11-38
-
-
Binz, S.K.1
Dickson, A.M.2
Haring, S.J.3
Wold, M.S.4
-
23
-
-
0030716255
-
Characterization of reaction intermediates of human excision repair nuclease
-
DOI 10.1074/jbc.272.46.28971
-
Mu, D., Wakasugi, M., Hsu, D. S., and Sancar, A. (1997) Characterization of reaction intermediates of human excision repair nuclease. J. Biol. Chem. 272, 28971-28979 (Pubitemid 27498182)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.46
, pp. 28971-28979
-
-
Mu, D.1
Wakasugi, M.2
Hsu, D.S.3
Sancar, A.4
-
24
-
-
0141753120
-
The comings and goings of nucleotide excision repair factors on damaged DNA
-
DOI 10.1093/emboj/cdg489
-
Riedl, T., Hanaoka, F., and Egly, J. M. (2003) The comings and goings of nucleotide excision repair factors on damaged DNA. EMBO J. 22, 5293-5303 (Pubitemid 37222048)
-
(2003)
EMBO Journal
, vol.22
, Issue.19
, pp. 5293-5303
-
-
Riedl, T.1
Hanaoka, F.2
Egly, J.-M.3
-
25
-
-
0030908093
-
Replication protein A. A heterotrimeric, singlestranded DNA-binding protein required for eukaryotic DNA metabolism
-
Wold, M. S. (1997) Replication protein A. A heterotrimeric, singlestranded DNA-binding protein required for eukaryotic DNA metabolism. Annu. Rev. Biochem. 66, 61-92
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 61-92
-
-
Wold, M.S.1
-
26
-
-
0142059994
-
Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease
-
DOI 10.1101/gad.1131003
-
Reardon, J. T., and Sancar, A. (2003) Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease. Genes Dev. 17, 2539-2551 (Pubitemid 37271424)
-
(2003)
Genes and Development
, vol.17
, Issue.20
, pp. 2539-2551
-
-
Reardon, J.T.1
Sancar, A.2
-
27
-
-
0030667311
-
Initiation of DNA interstrand cross-link repair in humans: The nucleotide excision repair system makes dual incisions 5' to the cross- linked base and removes a 22- to 28-nucleotide-long damage-free strand
-
Bessho, T., Mu, D., and Sancar, A. (1997) Initiation of DNA interstrand cross-link repair in humans. The nucleotide excision repair system makes dual incisions 5′ to the cross-linked base and removes a 22- to 28-nucleotide-long damage-free strand. Mol. Cell. Biol. 17, 6822-6830 (Pubitemid 27505911)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.12
, pp. 6822-6830
-
-
Bessho, T.1
Mu, D.2
Sancar, A.3
-
28
-
-
0001408659
-
Release of ultraviolet lightinduced thymine dimers from DNA in E. coli K-12
-
Boyce, R. P., and Howard-Flanders, P. (1964) Release of ultraviolet lightinduced thymine dimers from DNA in E. coli K-12. Proc. Natl. Acad. Sci. U.S.A. 51, 293-300
-
(1964)
Proc. Natl. Acad. Sci. U.S.A.
, vol.51
, pp. 293-300
-
-
Boyce, R.P.1
Howard-Flanders, P.2
-
29
-
-
0020184496
-
In vivo excision of pyrimidine dimers is mediated by aDNAN-glycosylase in Micrococcus luteus but not in human fibroblasts
-
La Belle, M., and Linn, S. (1982) In vivo excision of pyrimidine dimers is mediated by aDNAN-glycosylase in Micrococcus luteus but not in human fibroblasts. Photochem. Photobiol. 36, 319-324
-
(1982)
Photochem. Photobiol.
, vol.36
, pp. 319-324
-
-
La Belle, M.1
Linn, S.2
-
30
-
-
78651191735
-
The disappearance of thymine dimers from DNA. An error-correcting mechanism
-
Setlow, R. B., and Carrier, W. L. (1964) The disappearance of thymine dimers from DNA. An error-correcting mechanism. Proc. Natl. Acad. Sci. U.S.A. 51, 226-231
-
(1964)
Proc. Natl. Acad. Sci. U.S.A.
, vol.51
, pp. 226-231
-
-
Setlow, R.B.1
Carrier, W.L.2
-
31
-
-
0014257960
-
Evidence for excision of ultraviolet-induced pyrimidine dimers from the DNA of human cells in vitro
-
Regan, J. D., Trosko, J. E., and Carrier, W. L. (1968) Evidence for excision of ultraviolet-induced pyrimidine dimers from the DNA of human cells in vitro. Biophys. J. 8, 319-325
-
(1968)
Biophys. J.
, vol.8
, pp. 319-325
-
-
Regan, J.D.1
Trosko, J.E.2
Carrier, W.L.3
-
32
-
-
0014597052
-
Evidence that xeroderma pigmentosum cells do not perform the first step in the repair of ultraviolet damage to their DNA
-
Setlow, R. B., Regan, J. D., German, J., and Carrier, W. L. (1969) Evidence that xeroderma pigmentosum cells do not perform the first step in the repair of ultraviolet damage to their DNA. Proc. Natl. Acad. Sci. U.S.A. 64, 1035-1041
-
(1969)
Proc. Natl. Acad. Sci. U.S.A.
, vol.64
, pp. 1035-1041
-
-
Setlow, R.B.1
Regan, J.D.2
German, J.3
Carrier, W.L.4
-
33
-
-
0022530342
-
Photoreversal-dependent release of thymidine and thymidine monophosphate from pyrimidine dimer-containing DNA excision fragments isolated from ultraviolet-damaged human fibroblasts
-
Weinfeld, M., Gentner, N. E., Johnson, L. D., and Paterson, M. C. (1986) Photoreversal-dependent release of thymidine and thymidine monophosphate from pyrimidine dimer-containing DNA excision fragments isolated from ultraviolet-damaged human fibroblasts. Biochemistry. 25, 2656-2664 (Pubitemid 16075217)
-
(1986)
Biochemistry
, vol.25
, Issue.9
, pp. 2656-2664
-
-
Weinfeld, M.1
Gentner, N.E.2
Johnson, L.D.3
Paterson, M.C.4
-
34
-
-
0020641572
-
A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region
-
Sancar, A., and Rupp, W. D. (1983) A novel repair enzyme. UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region. Cell. 33, 249-260 (Pubitemid 13096454)
-
(1983)
Cell
, vol.33
, Issue.1
, pp. 249-260
-
-
Sancar, A.1
Rupp, W.D.2
-
35
-
-
0029741027
-
Overproduction, purification, and characterization of the XPC subunit of the human DNA repair excision nuclease
-
DOI 10.1074/jbc.271.32.19451
-
Reardon, J. T., Mu, D., and Sancar, A. (1996) Overproduction, purification, and characterization of the XPC subunit of the human DNA repair excision nuclease. J. Biol. Chem. 271, 19451-19456 (Pubitemid 26271618)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.32
, pp. 19451-19456
-
-
Reardon, J.T.1
Mu, D.2
Sancar, A.3
-
36
-
-
0032499719
-
Assembly, subunit composition, and footprint of human DNA repair excision nuclease
-
DOI 10.1073/pnas.95.12.6669
-
Wakasugi, M., and Sancar, A. (1998) Assembly, subunit composition, and footprint of human DNA repair excision nuclease. Proc. Natl. Acad. Sci. U.S.A. 95, 6669-6674 (Pubitemid 28278038)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.12
, pp. 6669-6674
-
-
Wakasugi, M.1
Sancar, A.2
-
37
-
-
0033603338
-
Order of assembly of human DNA repair excision nuclease
-
Wakasugi, M., and Sancar, A. (1999) Order of assembly of human DNA repair excision nuclease. J. Biol. Chem. 274, 18759-18768
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18759-18768
-
-
Wakasugi, M.1
Sancar, A.2
-
38
-
-
0036318818
-
Molecular anatomy of the human excision nuclease assembled at sites of DNA damage
-
DOI 10.1128/MCB.22.16.5938-5945.2002
-
Reardon, J. T., and Sancar, A. (2002) Molecular anatomy of the human excision nuclease assembled at sites of DNA damage. Mol. Cell. Biol. 22, 5938-5945 (Pubitemid 34815841)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.16
, pp. 5938-5945
-
-
Reardon, J.T.1
Sancar, A.2
-
39
-
-
0026595890
-
Post-incision steps of nucleotide excision repair in Escherichia coli. Disassembly of the UvrBC-DNA complex by helicase II and DNA polymerase I
-
Orren, D. K., Selby, C. P., Hearst, J. E., and Sancar, A. (1992) Post-incision steps of nucleotide excision repair in Escherichia coli. Disassembly of the UvrBC-DNA complex by helicase II and DNA polymerase I. J. Biol. Chem. 267, 780-788
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 780-788
-
-
Orren, D.K.1
Selby, C.P.2
Hearst, J.E.3
Sancar, A.4
-
40
-
-
0028178394
-
Identification of a 3′→ 5′-exonuclease that removes cytosine arabinoside monophosphate from 3′ termini of DNA
-
Perrino, F. W., Miller, H., and Ealey, K. A. (1994) Identification of a 3′→ 5′-exonuclease that removes cytosine arabinoside monophosphate from 3′ termini of DNA. J. Biol. Chem. 269, 16357-16363
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16357-16363
-
-
Perrino, F.W.1
Miller, H.2
Ealey, K.A.3
-
41
-
-
3242672339
-
Gene-targeted mice lacking the Trex1 (DNase III) 3′′5′ DNA exonuclease develop inflammatory myocarditis
-
DOI 10.1128/MCB.24.15.6719-6727.2004
-
Morita, M., Stamp, G., Robins, P., Dulic, A., Rosewell, I., Hrivnak, G., Daly, G., Lindahl, T., and Barnes, D. E. (2004) Gene-targeted mice lacking the Trex1 (DNase III) 3′→5′ DNA exonuclease develop inflammatory myocarditis. Mol. Cell. Biol. 24, 6719-6727 (Pubitemid 38944351)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.15
, pp. 6719-6727
-
-
Morita, M.1
Stamp, G.2
Robins, P.3
Dulic, A.4
Rosewell, I.5
Hrivnak, G.6
Daly, G.7
Lindahl, T.8
Barnes, D.E.9
-
42
-
-
47949121598
-
Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity
-
Jazayeri, A., Balestrini, A., Garner, E., Haber, J. E., and Costanzo, V. (2008) Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity. EMBO J. 27, 1953-1962
-
(2008)
EMBO J.
, vol.27
, pp. 1953-1962
-
-
Jazayeri, A.1
Balestrini, A.2
Garner, E.3
Haber, J.E.4
Costanzo, V.5
-
43
-
-
0029055808
-
Activation of p53 sequence-specific DNAbinding by short single strands ofDNArequires the p53 C-terminus
-
Jayaraman, J., and Prives, C. (1995) Activation of p53 sequence-specific DNAbinding by short single strands ofDNArequires the p53 C-terminus. Cell 81, 1021-1029
-
(1995)
Cell
, vol.81
, pp. 1021-1029
-
-
Jayaraman, J.1
Prives, C.2
|