Calpain induces N-terminal truncation of β-catenin in normal murine liver development: Diagnostic implications in hepatoblastomas

Journal of Biological Chemistry

Volumn 287, Issue 27, 2012, Pages 22789-22798

  Lade, Abigale ^a   Ranganathan, Sarangarajan ^a   Luo, Jianhua ^a   Monga, Satdarshan P S ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAINS; CATENIN SIGNALING; CELL-BASED ASSAYS; CELL-FREE; DIAGNOSTIC IMPLICATIONS; DOWNSTREAM TARGET; EPITHELIAL CELLS; HEPATOCYTES; HUMAN LIVER; INTRAPERITONEAL INJECTIONS; LATE STAGE; LIVER DEVELOPMENT; N-TERMINAL TRUNCATION; N-TERMINALS; PLEIOTROPIC ROLES; PROTEOLYTIC CLEAVAGE; SHORT TERM; TEMPORAL MODULATIONS; TRANSCRIPTIONALLY ACTIVE;

AMINO ACIDS; CELLS; RNA;

MAMMALS;

BETA CATENIN; CALPAIN; RNA;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CELL FREE SYSTEM; CELL PROLIFERATION; EPITHELIUM CELL; FEMALE; HEPATOBLASTOMA; LIVER CELL; LIVER DEVELOPMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RNA SEQUENCE; WNT SIGNALING PATHWAY;

ALTERNATIVE SPLICING; ANIMALS; BETA CATENIN; CALPAIN; CELL DIFFERENTIATION; CYSTEINE PROTEINASE INHIBITORS; DIPEPTIDES; FEMALE; HEK293 CELLS; HEPATOBLASTOMA; HEPATOCYTES; HUMANS; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C57BL; PREGNANCY; PROTEIN STRUCTURE, TERTIARY;

MURINAE; MUS;

EID: 84863306530     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.378224     Document Type: Article

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