Promoter demethylation of Keap1 gene in human diabetic cataractous lenses

Biochemical and Biophysical Research Communications

Volumn 423, Issue 3, 2012, Pages 542-548

  Palsamy, Periyasamy ^a   Ayaki, Masahiko ^b   Elanchezhian, Rajan ^a   Shinohara, Toshimichi ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b Shizuoka National Hospital   (Japan)

Author keywords

CpG islands; DNA demethylation; Keap1 promoter; Nrf2 dependent antioxidant protection; Proteosomal degradation; Unfolded protein response

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2;

ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CATARACT; CELL DEATH; COMPUTER MODEL; CPG ISLAND; DEMETHYLATION; DIABETES MELLITUS; DNA METHYLATION; DNA SEQUENCE; EPITHELIUM CELL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; LENS EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AZACITIDINE; CATARACT; CELLS, CULTURED; CPG ISLANDS; DIABETES COMPLICATIONS; DNA METHYLATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LENS, CRYSTALLINE; MIDDLE AGED; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC;

EID: 84863301644     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.05.164     Document Type: Article

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