Exposure to diesel exhaust upregulates COX-2 expression in ApoE knockout mice

Inhalation Toxicology

Volumn 24, Issue 8, 2012, Pages 518-527

  Bai, Ni ^a   Tranfield, Erin M ^b   Kavanagh, Terrance J ^c   Kaufman, Joel D ^c   Rosenfeld, Michael E ^c   Van Eeden, Stephan F ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

ApoE knockout mouse; Atherosclerosis; Cyclooxygenase; Diesel exhaust

Indexed keywords

2,3 DINOR 6 OXOPROSTAGLANDIN F1 ALPHA; APOLIPOPROTEIN E; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; INDOMETACIN; MESSENGER RNA; PHENYLEPHRINE; PROSTACYCLIN DERIVATIVE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; AORTA ROOT; ARTICLE; ATHEROSCLEROSIS; ATTENUATION; CONTROLLED STUDY; CORONARY ARTERY CONSTRICTION; ENDOTHELIUM CELL; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME INDUCTION; EXHAUST GAS; FILTRATION; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MOUSE; MYOGRAPHY; NONHUMAN; PARTICULATE MATTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; THORACIC AORTA; URINALYSIS;

ANIMALS; AORTA, THORACIC; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; ENDOTHELIUM, VASCULAR; IMMUNOHISTOCHEMISTRY; INDOMETHACIN; INHALATION EXPOSURE; MACROPHAGES; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UP-REGULATION; VASOCONSTRICTION; VEHICLE EMISSIONS;

MUS;

EID: 84863299285     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958378.2012.696221     Document Type: Article

References (41)

1. Bai N, Khazaei M, van Eeden SF, Laher I. 2007. The pharmacology of particulate matter air pollution-induced cardiovascular dysfunction. Pharmacol Ther 113:16-29. (Pubitemid 44969925)
2. Bai N, Kido T, Kavanagh TJ, Kaufman JD, Rosenfeld ME, van Breemen C, van Eeden SF. 2011a. Exposure to diesel exhaust up-regulates iNOS expression in ApoE knockout mice. Toxicol Appl Pharmacol 255:184-192.
3. Bai N, Kido T, Suzuki H, Yang G, Kavanagh TJ, Kaufman JD, Rosenfeld ME, van Breemen C, Eeden SF. 2011b. Changes in atherosclerotic plaques induced by inhalation of diesel exhaust. Atherosclerosis 216:299-306.
4. Barbieri SS, Weksler BB. 2007. Tobacco smoke cooperates with interleukin-1? to alter ?-catenin trafficking in vascular endothelium resulting in increased permeability and induction of cyclooxygenase-2 expression in vitro and in vivo. FASEB J 21:1831-1843. (Pubitemid 46855629)
5. Belton OA, Duffy A, Toomey S, Fitzgerald DJ. 2003. Cyclooxygenase isoforms and platelet vessel wall interactions in the apolipoprotein E knockout mouse model of atherosclerosis. Circulation 108:3017-3023. (Pubitemid 37553572)
6. Brook RD, Rajagopalan S, Pope CA 3rd, Brook JR, Bhatnagar A, Diez-Roux AV, Holguin F, Hong Y, Luepker RV, Mittleman MA, Peters A, Siscovick D, Smith SC Jr, Whitsel L, Kaufman JD; American Heart Association Council on Epidemiology and Prevention, Council on the Kidney in Cardiovascular Disease, and Council on Nutrition, Physical Activity and Metabolism. 2010. Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association. Circulation 121:2331-2378.
7. Burleigh ME, Babaev VR, Yancey PG, Major AS, McCaleb JL, Oates JA, Morrow JD, Fazio S, Linton MF. 2005. Cyclooxygenase-2 promotes early atherosclerotic lesion formation in ApoE-deficient and C57BL/6 mice. J Mol Cell Cardiol 39:443-452. (Pubitemid 41133730)
8. Campen MJ, Lund AK, Knuckles TL, Conklin DJ, Bishop B, Young D, Seilkop S, Seagrave J, Reed MD, McDonald JD. 2010. Inhaled diesel emissions alter atherosclerotic plaque composition in ApoE(-/-) mice. Toxicol Appl Pharmacol 242:310-317.
9. Cipollone F, Rocca B, Patrono C. 2004. Cyclooxygenase-2 expression and inhibition in atherothrombosis. Arterioscler Thromb Vasc Biol 24:246-255. (Pubitemid 38197575)
10. Dockery DW, Pope CA 3rd, Xu X, Spengler JD, Ware JH, Fay ME, Ferris BG Jr, Speizer FE. 1993. An association between air pollution and mortality in six U.S. cities. N Engl J Med 329:1753-1759. (Pubitemid 23355547)
11. Donaldson K, Stone V, Clouter A, Renwick L, MacNee W. 2001. Ultrafine particles. Occup Environ Med 58:211-6, 199.
12. Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, Van De Putte LB, Lipsky PE. 1998. Cyclooxygenase in biology and disease. FASEB J 12:1063-1073. (Pubitemid 28418937)
13. Egan KM, Lawson JA, Fries S, Koller B, Rader DJ, Smyth EM, Fitzgerald GA. 2004. COX-2-derived prostacyclin confers atheroprotection on female mice. Science 306:1954-1957. (Pubitemid 39627863)
14. Gould T, Larson T, Stewart J, Kaufman JD, Slater D, McEwen N. 2008. A controlled inhalation diesel exhaust exposure facility with dynamic feedback control of PM concentration. Inhal Toxicol 20:49-52. (Pubitemid 351194915)
15. Hermann M, Camici G, Fratton A, Hurlimann D, Tanner FC, Hellermann JP, Fiedler M, Thiery J, Neidhart M, Gay RE, Gay S, Lüscher TF, Ruschitzka F. 2003. Differential effects of selective cyclooxygenase-2 inhibitors on endothelial function in saltinduced hypertension. Circulation 108:2308-2311. (Pubitemid 37413534)
16. Hofer TP, Bitterle E, Beck-Speier I, Maier KL, Frankenberger M, Heyder J, Ziegler-Heitbrock L. 2004. Diesel exhaust particles increase LPSstimulated COX-2 expression and PGE2 production in human monocytes. J Leukoc Biol 75:856-864. (Pubitemid 38580066)
17. Hoek G, Brunekreef B, Goldbohm S, Fischer P, van den Brandt PA. 2002. Association between mortality and indicators of trafficrelated air pollution in the Netherlands: A cohort study. Lancet 360:1203-1209. (Pubitemid 35232719)
18. Ishii H, Fujii T, Hogg JC, Hayashi S, Mukae H, Vincent R, van Eeden SF. 2004. Contribution of IL-1 ? and TNF-? to the initiation of the peripheral lung response to atmospheric particulates (PM10). Am J Physiol Lung Cell Mol Physiol 287:L176-L183. (Pubitemid 38787664)
19. Kalyanaraman B, Mason RP, Tainer B, Eling TE. 1982. The free radical formed during the hydroperoxide-mediated deactivation of ram seminal vesicles is hemoprotein-derived. J Biol Chem 257:4764-4768.
20. Karthein R, Nastainczyk W, Ruf HH. 1987. EPR study of ferric native prostaglandin H synthase and its ferrous NO derivative. Eur J Biochem 166:173-180.
21. Kawabe J, Ushikubi F, Hasebe N. 2010a. Prostacyclin in vascular diseases. Recent insights and future perspectives. Circ J 74:836-843.
22. Kawabe J, Yuhki K, Okada M, Kanno T, Yamauchi A, Tashiro N, Sasaki T, Okumura S, Nakagawa N, Aburakawa Y, Takehara N, Fujino T, Hasebe N, Narumiya S, Ushikubi F. 2010a. Prostaglandin I2 promotes recruitment of endothelial progenitor cells and limits vascular remodeling. Arterioscler Thromb Vasc Biol 30: 464-470.
23. Kido T, Bai N, Yatera K, Suzuki H, Meredith A, Mukae H, Rosenfeld ME, van Eeden SF. 2011. Diesel exhaust inhalation induces heat shock protein 70 expression in vivo. Inhal Toxicol 23: 593-601.
24. Kim SF, Huri DA, Snyder SH. 2005. Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2. Science 310:1966-1970. (Pubitemid 43005992)
25. Li SL, Reddy MA, Cai Q, Meng L, Yuan H, Lanting L, Natarajan R. 2006. Enhanced proatherogenic responses in macrophages and vascular smooth muscle cells derived from diabetic db/db mice. Diabetes 55:2611-2619. (Pubitemid 44871163)
26. McClelland S, Gawaz M, Kennerknecht E, Konrad CS, Sauer S, Schuerzinger K, Massberg S, Fitzgerald DJ, Belton O. 2009. Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse. Atherosclerosis 202:84-91.
27. Praticò D, Tillmann C, Zhang ZB, Li H, FitzGerald GA. 2001. Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice. Proc Natl Acad Sci USA 98:3358-3363. (Pubitemid 32220850)
28. Racz A, Veresh Z, Lotz G, Bagi Z, Koller A. 2010. Cyclooxygenase-2 derived thromboxane A(2) and reactive oxygen species mediate flow-induced constrictions of venules in hyperhomocysteinemia. Atherosclerosis 208:43-49.
29. Rott D, Zhu J, Burnett MS, Zhou YF, Zalles-Ganley A, Ogunmakinwa J, Epstein SE. 2003. Effects of MF-tricyclic, a selective cyclooxygenase-2 inhibitor, on atherosclerosis progression and susceptibility to cytomegalovirus replication in apolipoprotein-E knockout mice. J Am Coll Cardiol 41:1812-1819. (Pubitemid 36584257)
30. Samet JM, Ghio AJ, Costa DL, Madden MC. 2000. Increased expression of cyclooxygenase 2 mediates oil fly ash-induced lung injury. Exp Lung Res 26:57-69. (Pubitemid 30043887)
31. Schönbeck U, Sukhova GK, Graber P, Coulter S, Libby P. 1999. Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions. Am J Pathol 155:1281-1291. (Pubitemid 29488935)
32. Schuetzle D, Lee FS, Prater TJ. 1981. The identification of polynuclear aromatic hydrocarbon (PAH) derivatives in mutagenic fractions of diesel particulate extracts. Int J Environ Anal Chem 9: 93-144. (Pubitemid 11004171)
33. Seaton A, MacNee W, Donaldson K, Godden D. 1995. Particulate air pollution and acute health effects. Lancet 345:176-178.
34. Sun Q, Wang A, Jin X, Natanzon A, Duquaine D, Brook RD, Aguinaldo JG, Fayad ZA, Fuster V, Lippmann M, Chen LC, Rajagopalan S. 2005. Long-term air pollution exposure and acceleration of atherosclerosis and vascular inflammation in an animal model. JAMA 294:3003-3010. (Pubitemid 41817662)
35. Suwa T, Hogg JC, Quinlan KB, Ohgami A, Vincent R, van Eeden SF. 2002. Particulate air pollution induces progression of atherosclerosis. J Am Coll Cardiol 39:935-942. (Pubitemid 34234112)
36. Tamagawa E, Bai N, Morimoto K, Gray C, Mui T, Yatera K, Zhang X, Xing L, Li Y, Laher I, Sin DD, Man SF, van Eeden SF. 2008. Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction. Am J Physiol Lung Cell Mol Physiol 295:L79-L85.
37. Virdis A, Colucci R, Fornai M, Duranti E, Giannarelli C, Bernardini N, Segnani C, Ippolito C, Antonioli L, Blandizzi C, Taddei S, Salvetti A, Del Tacca M. 2007. Cyclooxygenase-1 is involved in endothelial dysfunction of mesenteric small arteries from angiotensin II-infused mice. Hypertension 49:679-686.
38. Vogel CF, Sciullo E, Wong P, Kuzmicky P, Kado N, Matsumura F. 2005. Induction of proinflammatory cytokines and C-reactive protein in human macrophage cell line U937 exposed to air pollution particulates. Environ Health Perspect 113:1536-1541. (Pubitemid 41614908)
39. Warner TD, Mitchell JA. 2004. Cyclooxygenases: New forms, new inhibitors, and lessons from the clinic. FASEB J 18: 790-804. (Pubitemid 38544498)
40. Ye Y, Martinez JD, Perez-Polo RJ, Lin Y, Uretsky BF, Birnbaum Y. 2008. The role of eNOS, iNOS, and NF-?B in upregulation and activation of cyclooxygenase-2 and infarct size reduction by atorvastatin. Am J Physiol Heart Circ Physiol 295:H343-H351.
41. Zhao Y, Usatyuk PV, Gorshkova IA, He D, Wang T, Moreno-Vinasco L, Geyh AS, Breysse PN, Samet JM, Spannhake EW, Garcia JG, Natarajan V. 2009. Regulation of COX-2 expression and IL-6 release by particulate matter in airway epithelial cells. Am J Respir Cell Mol Biol 40:19-30.