Steroid receptor coactivator-3 differentially regulates the inflammatory response in peritoneal macrophages

Molecular Medicine Reports

Volumn 5, Issue 4, 2012, Pages 1099-1105

  Li, Jun ^a   Liu, Ying Hai ^a   Ou, Shan ^a   Dai, Xue Mei ^a   Wang, Jun Ping ^b   Su, Yong Ping ^b  

^a CHENGDU MILITARY GENERAL HOSPITAL   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Peritoneal macrophages; Steroid receptor coactivator 3; Systemic inflammatory response syndrome

Indexed keywords

GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; STEROID RECEPTOR COACTIVATOR 3; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; INFLAMMATION; INNATE IMMUNITY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PHAGOCYTOSIS; PROTEIN FUNCTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELL SEPARATION; INTERLEUKIN-10; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; NUCLEAR RECEPTOR COACTIVATOR 3; RECEPTORS, GLUCOCORTICOID; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

MUS;

EID: 84863294259     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.750     Document Type: Article

References (26)

1. Webster JC, Oakley RH, Jewell CM and Cidlowski JA: Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative beta isoform: a mechanism for the generation of glucocorticoid resistance. Proc Natl Acad Sci USA 98: 6865-6870, 2001. (Pubitemid 32538308)
2. Goecke A and Guerrero J: Glucocorticoid receptor beta in acute and chronic inflammatory conditions: clinical implications. Immunobiology 211: 85-96, 2006. (Pubitemid 43150110)
3. Liao L, Kuang SQ, Yuan Y, Gonzalez SM, O'Malley BW and Xu J: Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. J Steroid Biochem Mol Biol 83: 3-14, 2002. (Pubitemid 37040636)
4. Gojis O, Rudraraju B, Alifrangis C, Krell J, Libalova P and Palmieri C: The role of steroid receptor coactivator-3 (SRC-3) in human malignant disease. Eur J Surg Oncol 36: 224-229, 2010.
5. Lydon JP and O'Malley BW: Minireview: steroid receptor coactivator-3: a multifarious coregulator in mammary gland metastasis. Endocrinology 152: 19-25, 2011.
6. Kurihara I, Shibata H, Suzuki T, et al: Transcriptional regulation of steroid receptor coactivator-1 (SRC-1) in glucocorticoid action. Endocr Res 26: 1033-1038, 2000. (Pubitemid 32053138)
7. Iwasaka H and Noguchi T: Th1/Th2 balance in systemic inflammatory response syndrome (SIRS). Nippon-Rinsho 62: 2237-2243, 2004 (In Japanese).
8. Rumbaugh KP, Colmer JA, Griswold JA and Hamood AN: The effects of infection of thermal injury by Pseudomonas aeruginosa PAO1 on the murine cytokine response. Cytokine 16: 160-168, 2001. (Pubitemid 34112121)
9. Parihar A, Parihar MS, Milner S and Bhat S: Oxidative stress and anti-oxidative mobilization in burn injury. Burns 34: 6-17, 2008.
10. Li J, Su YP, Liu HN, Lou SF, Huang YS, Jiang JX and Wang JP: Diazepam-ketamine inhibits 3 kinds of serum inflammatory cytokines during the early stage in burned mice. Acta Academiae Medicinae Militaris Tertiae 26: 1-14, 2004.
11. Schwacha MG: Macrophages and post-burn immune dysfunction. Burns 29: 1-14, 2003.
12. Mackrell PJ, Daly JM, Mestre JR, et al: Elevated expression of cyclooxygenase-2 contributes to immune dysfunction in a murine model of trauma. Surgery 130: 826-833, 2001. (Pubitemid 33022390)
13. Deitch EA: Multiple organ failure. Pathophysiology and potential future therapy. Ann Surg 216: 117-134, 1992.
14. Du ZY and Su YP: Breeding, reproducing and identifying SRC-3 knock-out mice. Acta Academiae Medicinae Militaris Tertiae 27: 373-375, 2005.
15. Sester DP, Trieu A, Brion K, et al: LPS regulates a set of genes in primary murine macrophages by antagonising CSF-1 action. Immunobiology 210: 97-107, 2005. (Pubitemid 41025150)
16. Gerard C, Bruyns C, Marchant A, et al: Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia. J Exp Med 177: 547-550, 1993. (Pubitemid 23117107)
17. Auphan N, DiDonato JA, Rosette C, et al: Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 270: 286-290, 1995.
18. Riccardi C, Cifone MG and Migliorati G: Glucocorticoid hormone-induced modulation of gene expression and regulation of T-cell death: role of GITR and GILZ, two dexamethasone-induced genes. Cell Death Differ 6: 1182-1189, 1999. (Pubitemid 30047895)
19. Scheinman RI, Cogswell PC, Lofquist AK and Baldwin AS Jr: Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 270: 283-286, 1995.
20. Ogawa S, Lozach J, Benner C, et al: Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell 122: 707-721, 2005. (Pubitemid 41242636)
21. Wullaert A: Role of NF-kappaB activation in intestinal immune homeostasis. Int J Med Microbiol 300: 49-56, 2010.
22. Caradonna L, Mastronardi ML, Magrone T, et al: Biological and clinical significance of endotoxemia in the course of hepatitis C virus infection. Curr Pharm Des 8: 995-1005, 2002. (Pubitemid 34506400)
23. Werbajh S, Nojek I, Lanz R and Costas MA: RAC-3 is a NF-kappaB coactivator. FEBS Lett 485: 195-199, 2000.
24. Lo CJ, Cryer HG, Fu M and Lo FR: Regulation of macrophage eicosanoid generation is dependent on nuclear factor kappaB. J Trauma 45: 19-23, 1998.
25. Chen C, Chen YH and Lin WW: Involvement of p38 mitogen-activated protein kinase in lipopolysaccharide-induced iNOS and COX-2 expression in J774 macrophages. Immunology 97: 124-129, 1999.
26. Sigal LH: Basic science for the clinician 43: the mitogen-activated protein kinase family in inflammatory signaling. J Clin Rheumatol 13: 96-99, 2007.