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Volumn 7, Issue 3, 2012, Pages

Chemotherapeutics and radiation stimulate MHC class i expression through elevated interferon-beta signaling in breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BETA INTERFERON; CISPLATIN; ETOPOSIDE; INTERFERON RECEPTOR; INTERLEUKIN 6; INTERLEUKIN 8; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PACLITAXEL; TOPOTECAN; TUMOR NECROSIS FACTOR ALPHA; VINBLASTINE; HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

EID: 84863291227     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032542     Document Type: Article
Times cited : (243)

References (51)
  • 1
    • 24944478531 scopus 로고    scopus 로고
    • Leveraging the Activity of Tumor Vaccines with Cytotoxic Chemotherapy
    • Emens LA, Jaffee EM, (2005) Leveraging the Activity of Tumor Vaccines with Cytotoxic Chemotherapy. Cancer Research 65: 8059-8064.
    • (2005) Cancer Research , vol.65 , pp. 8059-8064
    • Emens, L.A.1    Jaffee, E.M.2
  • 2
    • 77955172181 scopus 로고    scopus 로고
    • Metronomic chemotherapy: new rationale for new directions
    • Pasquier E, Kavallaris M, Andre N, (2010) Metronomic chemotherapy: new rationale for new directions. Nat Rev Clin Oncol 7: 455-465.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 455-465
    • Pasquier, E.1    Kavallaris, M.2    Andre, N.3
  • 3
    • 77957992952 scopus 로고    scopus 로고
    • Chemoimmunotherapy
    • Emens LA, (2010) Chemoimmunotherapy. Cancer J 16: 9.
    • (2010) Cancer J , vol.16 , pp. 9
    • Emens, L.A.1
  • 4
    • 0035328683 scopus 로고    scopus 로고
    • Cyclophosphamide, Doxorubicin, and Paclitaxel Enhance the Antitumor Immune Response of Granulocyte/Macrophage-Colony Stimulating Factor-secreting Whole-Cell Vaccines in HER-2/neu Tolerized Mice
    • Machiels J-PH, Reilly RT, Emens LA, Ercolini AM, Lei RY, et al. (2001) Cyclophosphamide, Doxorubicin, and Paclitaxel Enhance the Antitumor Immune Response of Granulocyte/Macrophage-Colony Stimulating Factor-secreting Whole-Cell Vaccines in HER-2/neu Tolerized Mice. Cancer Research 61: 3689-3697.
    • (2001) Cancer Research , vol.61 , pp. 3689-3697
    • Machiels, J.-P.H.1    Reilly, R.T.2    Emens, L.A.3    Ercolini, A.M.4    Lei, R.Y.5
  • 5
    • 33846004208 scopus 로고    scopus 로고
    • Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells
    • Salem ML, Kadima AN, El-Naggar SA, Rubinstein MP, Chen Y, et al. (2007) Defining the ability of cyclophosphamide preconditioning to enhance the antigen-specific CD8+ T-cell response to peptide vaccination: creation of a beneficial host microenvironment involving type I IFNs and myeloid cells. J Immunother 30: 14.
    • (2007) J Immunother , vol.30 , pp. 14
    • Salem, M.L.1    Kadima, A.N.2    El-Naggar, S.A.3    Rubinstein, M.P.4    Chen, Y.5
  • 6
    • 40949157885 scopus 로고    scopus 로고
    • Allogeneic Granulocyte Macrophage Colony-Stimulating Factor-Secreting Tumor Immunotherapy Alone or in Sequence with Cyclophosphamide for Metastatic Pancreatic Cancer: A Pilot Study of Safety, Feasibility, and Immune Activation
    • Laheru D, Lutz E, Burke J, Biedrzycki B, Solt S, et al. (2008) Allogeneic Granulocyte Macrophage Colony-Stimulating Factor-Secreting Tumor Immunotherapy Alone or in Sequence with Cyclophosphamide for Metastatic Pancreatic Cancer: A Pilot Study of Safety, Feasibility, and Immune Activation. Clinical Cancer Research 14: 1455-1463.
    • (2008) Clinical Cancer Research , vol.14 , pp. 1455-1463
    • Laheru, D.1    Lutz, E.2    Burke, J.3    Biedrzycki, B.4    Solt, S.5
  • 8
    • 0023182961 scopus 로고
    • Effect of low dose cyclophosphamide on the immune system of cancer patients: reduction of T-suppressor function without depletion of the CD8+ subset
    • Berd D, Mastrangelo MJ, (1987) Effect of low dose cyclophosphamide on the immune system of cancer patients: reduction of T-suppressor function without depletion of the CD8+ subset. Cancer Res 47: 3317-3321.
    • (1987) Cancer Res , vol.47 , pp. 3317-3321
    • Berd, D.1    Mastrangelo, M.J.2
  • 9
    • 59449100645 scopus 로고    scopus 로고
    • Paclitaxel reduces regulatory T cell numbers and inhibitory function and enhances the anti-tumor effects of the TLR9 agonist PF-3512676 in the mouse
    • Vicari AP, Luu R, Zhang N, Patel S, Makinen SR, et al. (2009) Paclitaxel reduces regulatory T cell numbers and inhibitory function and enhances the anti-tumor effects of the TLR9 agonist PF-3512676 in the mouse. Cancer Immunol Immunother 58: 615-628.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 615-628
    • Vicari, A.P.1    Luu, R.2    Zhang, N.3    Patel, S.4    Makinen, S.R.5
  • 10
    • 47649119341 scopus 로고    scopus 로고
    • Pretreatment with cisplatin enhances E7-specific CD8+ T-Cell-mediated antitumor immunity induced by DNA vaccination
    • Tseng CW, Hung CF, Alvarez RD, Trimble C, Huh WK, et al. (2008) Pretreatment with cisplatin enhances E7-specific CD8+ T-Cell-mediated antitumor immunity induced by DNA vaccination. Clin Cancer Res 14: 3185-3192.
    • (2008) Clin Cancer Res , vol.14 , pp. 3185-3192
    • Tseng, C.W.1    Hung, C.F.2    Alvarez, R.D.3    Trimble, C.4    Huh, W.K.5
  • 11
  • 14
    • 34250621776 scopus 로고    scopus 로고
    • Functional Up-regulation of Human Leukocyte Antigen Class I Antigens Expression by 5-aza-2′-deoxycytidine in Cutaneous Melanoma: Immunotherapeutic Implications
    • Fonsatti E, Nicolay HJM, Sigalotti L, Calabrò L, Pezzani L, et al. (2007) Functional Up-regulation of Human Leukocyte Antigen Class I Antigens Expression by 5-aza-2′-deoxycytidine in Cutaneous Melanoma: Immunotherapeutic Implications. Clinical Cancer Research 13: 3333-3338.
    • (2007) Clinical Cancer Research , vol.13 , pp. 3333-3338
    • Fonsatti, E.1    Nicolay, H.J.M.2    Sigalotti, L.3    Calabrò, L.4    Pezzani, L.5
  • 15
    • 39749119942 scopus 로고    scopus 로고
    • Next generation topoisomerase I inhibitors: Rationale and biomarker strategies
    • Teicher BA, (2008) Next generation topoisomerase I inhibitors: Rationale and biomarker strategies. Biochem Pharmacol 75: 1262-1271.
    • (2008) Biochem Pharmacol , vol.75 , pp. 1262-1271
    • Teicher, B.A.1
  • 17
    • 33749034730 scopus 로고    scopus 로고
    • Topoisomerase I inhibitors: camptothecins and beyond
    • Pommier Y, (2006) Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer 6: 789-802.
    • (2006) Nat Rev Cancer , vol.6 , pp. 789-802
    • Pommier, Y.1
  • 18
    • 84863297176 scopus 로고    scopus 로고
    • Induction of tumor-specific antitumor immunity after chemotherapy with cisplatin in mice bearing MOPC-104E plasmacytoma by modulation of MHC expression on tumor surface
    • Nio Y, Hirahara N, Minari Y, Iguchi C, Yamasawa K, et al. (2003) Induction of tumor-specific antitumor immunity after chemotherapy with cisplatin in mice bearing MOPC-104E plasmacytoma by modulation of MHC expression on tumor surface. Anticancer Res 20: 7.
    • (2003) Anticancer Res , vol.20 , pp. 7
    • Nio, Y.1    Hirahara, N.2    Minari, Y.3    Iguchi, C.4    Yamasawa, K.5
  • 19
    • 0024420685 scopus 로고
    • Arrest of Replication Forks by Drug-stabilized Topoisomerase I-DNA Cleavable Complexes as a Mechanism of Cell Killing by Camptothecin
    • Hsiang Y-H, Lihou MG, Liu LF, (1989) Arrest of Replication Forks by Drug-stabilized Topoisomerase I-DNA Cleavable Complexes as a Mechanism of Cell Killing by Camptothecin. Cancer Research 49: 5077-5082.
    • (1989) Cancer Research , vol.49 , pp. 5077-5082
    • Hsiang, Y.-H.1    Lihou, M.G.2    Liu, L.F.3
  • 20
    • 0027262981 scopus 로고
    • Footprinting of Individual Tumors and Their Variants by Constitutive Cytokine Expression Patterns
    • Pekarek LA, Weichselbaum RR, Beckett MA, Nachman J, Schreiber H, (1993) Footprinting of Individual Tumors and Their Variants by Constitutive Cytokine Expression Patterns. Cancer Research 53: 1978-1981.
    • (1993) Cancer Research , vol.53 , pp. 1978-1981
    • Pekarek, L.A.1    Weichselbaum, R.R.2    Beckett, M.A.3    Nachman, J.4    Schreiber, H.5
  • 22
    • 0002965441 scopus 로고    scopus 로고
    • Angiogenin, interleukins, and growth-factor levels in serum of patients with ovarian cancer: correlation with angiogenesis
    • Chopra V, Dinh TV, Hannigan EV, (1996) Angiogenin, interleukins, and growth-factor levels in serum of patients with ovarian cancer: correlation with angiogenesis. Cancer J Sci Am 2: 279-285.
    • (1996) Cancer J Sci Am , vol.2 , pp. 279-285
    • Chopra, V.1    Dinh, T.V.2    Hannigan, E.V.3
  • 23
    • 0030896584 scopus 로고    scopus 로고
    • Serum levels of interleukins, growth factors and angiogenin in patients with endometrial cancer
    • Chopra V, Dinh TV, Hannigan EV, (1997) Serum levels of interleukins, growth factors and angiogenin in patients with endometrial cancer. J Cancer Res Clin Oncol 123: 167-172.
    • (1997) J Cancer Res Clin Oncol , vol.123 , pp. 167-172
    • Chopra, V.1    Dinh, T.V.2    Hannigan, E.V.3
  • 24
    • 0030834459 scopus 로고    scopus 로고
    • MHC class I and II expression in prostate carcinoma and modulation by interferon-alpha and -gamma
    • Bander NH, Yao D, Liu H, Chen Y-T, Steiner M, et al. (1997) MHC class I and II expression in prostate carcinoma and modulation by interferon-alpha and-gamma. The Prostate 33: 233-239.
    • (1997) The Prostate , vol.33 , pp. 233-239
    • Bander, N.H.1    Yao, D.2    Liu, H.3    Chen, Y.-T.4    Steiner, M.5
  • 25
    • 77956542044 scopus 로고    scopus 로고
    • Interferon (IFN) beta treatment induces major histocompatibility complex (MHC) class I expression in the spinal cord and enhances axonal growth and motor function recovery following sciatic nerve crush in mice
    • Zanon RG, Cartarozzi LP, Victório SCS, Moraes JC, Morari J, et al. (2010) Interferon (IFN) beta treatment induces major histocompatibility complex (MHC) class I expression in the spinal cord and enhances axonal growth and motor function recovery following sciatic nerve crush in mice. Neuropathology and Applied Neurobiology 36: 515-534.
    • (2010) Neuropathology and Applied Neurobiology , vol.36 , pp. 515-534
    • Zanon, R.G.1    Cartarozzi, L.P.2    Victório, S.C.S.3    Moraes, J.C.4    Morari, J.5
  • 26
    • 33751257187 scopus 로고    scopus 로고
    • The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: Friend or foe?
    • Andersen JB, Hassel BA, (2006) The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: Friend or foe? Cytokine & Growth Factor Reviews 17: 411-421.
    • (2006) Cytokine & Growth Factor Reviews , vol.17 , pp. 411-421
    • Andersen, J.B.1    Hassel, B.A.2
  • 27
    • 0034923502 scopus 로고    scopus 로고
    • DNA TOPOISOMERASES: Structure, Function, and Mechanism
    • Champoux JJ, (2001) DNA TOPOISOMERASES: Structure, Function, and Mechanism. Annual Review of Biochemistry 70: 369-413.
    • (2001) Annual Review of Biochemistry , vol.70 , pp. 369-413
    • Champoux, J.J.1
  • 28
    • 0036689830 scopus 로고    scopus 로고
    • NF-kappaB activation and inhibition: a review
    • Sun Z, Andersson R, (2002) NF-kappaB activation and inhibition: a review. Shock 18: 8.
    • (2002) Shock , vol.18 , pp. 8
    • Sun, Z.1    Andersson, R.2
  • 29
    • 0025215386 scopus 로고
    • Different pathways mediate virus inducibility of the human IFN-[alpha]1 and IFN-[beta] genes
    • MacDonald NJ, Kuhl D, Maguire D, Näf D, Gallant P, et al. (1990) Different pathways mediate virus inducibility of the human IFN-[alpha]1 and IFN-[beta] genes. Cell 60: 767-779.
    • (1990) Cell , vol.60 , pp. 767-779
    • MacDonald, N.J.1    Kuhl, D.2    Maguire, D.3    Näf, D.4    Gallant, P.5
  • 31
    • 33845237407 scopus 로고    scopus 로고
    • NF-kB inhibition as a strategy to enhance etoposide-induced apoptosis in K562 cell line
    • Morotti A, Cilloni D, Pautasso M, Messa F, Arruga F, et al. (2006) NF-kB inhibition as a strategy to enhance etoposide-induced apoptosis in K562 cell line. Am J Hematol 81: 8.
    • (2006) Am J Hematol , vol.81 , pp. 8
    • Morotti, A.1    Cilloni, D.2    Pautasso, M.3    Messa, F.4    Arruga, F.5
  • 32
    • 2942702021 scopus 로고    scopus 로고
    • Suppression of MEK/ERK Signaling Pathway Enhances Cisplatin-induced NF-κB Activation by Protein Phosphatase 4-mediated NF-κB p65 Thr Dephosphorylation
    • Yeh PY, Yeh K-H, Chuang S-E, Song YC, Cheng A-L, (2004) Suppression of MEK/ERK Signaling Pathway Enhances Cisplatin-induced NF-κB Activation by Protein Phosphatase 4-mediated NF-κB p65 Thr Dephosphorylation. Journal of Biological Chemistry 279: 26143-26148.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 26143-26148
    • Yeh, P.Y.1    Yeh, K.-H.2    Chuang, S.-E.3    Song, Y.C.4    Cheng, A.-L.5
  • 33
    • 0030610472 scopus 로고    scopus 로고
    • Activation of NF-κB by Antineoplastic Agents
    • Das KC, White CW, (1997) Activation of NF-κB by Antineoplastic Agents. Journal of Biological Chemistry 272: 14914-14920.
    • (1997) Journal of Biological Chemistry , vol.272 , pp. 14914-14920
    • Das, K.C.1    White, C.W.2
  • 34
    • 0035452254 scopus 로고    scopus 로고
    • S phase dependence and involvement of NF-kappaB activating kinase to NF-kappaB activation by camptothecin
    • Habraken Y, Piret B, Piette J, (2001) S phase dependence and involvement of NF-kappaB activating kinase to NF-kappaB activation by camptothecin. Biochemical Pharmacology 62: 603-616.
    • (2001) Biochemical Pharmacology , vol.62 , pp. 603-616
    • Habraken, Y.1    Piret, B.2    Piette, J.3
  • 35
    • 0030772376 scopus 로고    scopus 로고
    • Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo
    • Pierce JW, Schoenleber R, Jesmok G, Best J, Moore SA, et al. (1997) Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem 272: 21096-21103.
    • (1997) J Biol Chem , vol.272 , pp. 21096-21103
    • Pierce, J.W.1    Schoenleber, R.2    Jesmok, G.3    Best, J.4    Moore, S.A.5
  • 36
    • 33845210398 scopus 로고    scopus 로고
    • Analysis of cyclin B1 and CDK activity during apoptosis induced by camptothecin treatment
    • Borgne A, Versteege I, Mahe M, Studeny A, Leonce S, et al. (2006) Analysis of cyclin B1 and CDK activity during apoptosis induced by camptothecin treatment. Oncogene 25: 7361-7372.
    • (2006) Oncogene , vol.25 , pp. 7361-7372
    • Borgne, A.1    Versteege, I.2    Mahe, M.3    Studeny, A.4    Leonce, S.5
  • 37
    • 0033178444 scopus 로고    scopus 로고
    • Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons
    • Stefanis L, Park DS, Friedman WJ, Greene LA, (1999) Caspase-dependent and-independent death of camptothecin-treated embryonic cortical neurons. J Neurosci 19: 6235-6247.
    • (1999) J Neurosci , vol.19 , pp. 6235-6247
    • Stefanis, L.1    Park, D.S.2    Friedman, W.J.3    Greene, L.A.4
  • 39
    • 0032573165 scopus 로고    scopus 로고
    • Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms
    • Li N, Karin M, (1998) Ionizing radiation and short wavelength UV activate NF-kappaB through two distinct mechanisms. Proc Natl Acad Sci U S A 95: 13012-13017.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 13012-13017
    • Li, N.1    Karin, M.2
  • 40
    • 52949121004 scopus 로고    scopus 로고
    • Does chemotherapy augment anti-tumor immunotherapy by preferential impairment of regulatory T cells?
    • Zhang L, Dermawan KT, Jin ML, Xiong SD, Chu YW, (2008) Does chemotherapy augment anti-tumor immunotherapy by preferential impairment of regulatory T cells? Med Hypotheses 71: 802-804.
    • (2008) Med Hypotheses , vol.71 , pp. 802-804
    • Zhang, L.1    Dermawan, K.T.2    Jin, M.L.3    Xiong, S.D.4    Chu, Y.W.5
  • 41
    • 0034653477 scopus 로고    scopus 로고
    • Cyclophosphamide induces type I interferon and augments the number of CD44hi T lymphocytes in mice: implications for strategies of chemoimmunotherapy of cancer
    • Schiavoni G, Mattei F, Di Pucchio T, Santini SM, Bracci L, et al. (2000) Cyclophosphamide induces type I interferon and augments the number of CD44hi T lymphocytes in mice: implications for strategies of chemoimmunotherapy of cancer. Blood 95: 2024-2030.
    • (2000) Blood , vol.95 , pp. 2024-2030
    • Schiavoni, G.1    Mattei, F.2    Di Pucchio, T.3    Santini, S.M.4    Bracci, L.5
  • 42
    • 30444439232 scopus 로고    scopus 로고
    • Importance of signaling via the IFN-α/β receptor on host cells for the realization of the therapeutic benefits of cyclophosphamide for mice bearing a large MOPC-315 tumor
    • Mokyr M, Place A, Artwohl J, Valli VE, (2006) Importance of signaling via the IFN-α/β receptor on host cells for the realization of the therapeutic benefits of cyclophosphamide for mice bearing a large MOPC-315 tumor. Cancer Immunology, Immunotherapy 55: 459-468.
    • (2006) Cancer Immunology, Immunotherapy , vol.55 , pp. 459-468
    • Mokyr, M.1    Place, A.2    Artwohl, J.3    Valli, V.E.4
  • 43
    • 0032518412 scopus 로고    scopus 로고
    • Importance of cyclophosphamide-induced bystander effect on T cells for a successful tumor eradication in response to adoptive immunotherapy in mice
    • Proietti E, Greco G, Garrone B, Baccarini S, Mauri C, et al. (1998) Importance of cyclophosphamide-induced bystander effect on T cells for a successful tumor eradication in response to adoptive immunotherapy in mice. The Journal of Clinical Investigation 101: 429-441.
    • (1998) The Journal of Clinical Investigation , vol.101 , pp. 429-441
    • Proietti, E.1    Greco, G.2    Garrone, B.3    Baccarini, S.4    Mauri, C.5
  • 44
    • 0345734266 scopus 로고    scopus 로고
    • Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administration
    • Teitz-Tennenbaum S, Li Q, Rynkiewicz S, Ito F, Davis MA, et al. (2003) Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administration. Cancer Res 63: 8466-8475.
    • (2003) Cancer Res , vol.63 , pp. 8466-8475
    • Teitz-Tennenbaum, S.1    Li, Q.2    Rynkiewicz, S.3    Ito, F.4    Davis, M.A.5
  • 45
    • 33646704729 scopus 로고    scopus 로고
    • Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy
    • Reits EA, Hodge JW, Herberts CA, Groothuis TA, Chakraborty M, et al. (2006) Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. The Journal of Experimental Medicine 203: 1259-1271.
    • (2006) The Journal of Experimental Medicine , vol.203 , pp. 1259-1271
    • Reits, E.A.1    Hodge, J.W.2    Herberts, C.A.3    Groothuis, T.A.4    Chakraborty, M.5
  • 46
    • 33746353433 scopus 로고    scopus 로고
    • Bystander effects are induced by CENU treatment and associated with altered protein secretory activity of treated tumor cells A relay for chemotherapy?
    • Demidem A, Morvan D, Madelmont JC, (2006) Bystander effects are induced by CENU treatment and associated with altered protein secretory activity of treated tumor cells A relay for chemotherapy? International Journal of Cancer 119: 992-1004.
    • (2006) International Journal of Cancer , vol.119 , pp. 992-1004
    • Demidem, A.1    Morvan, D.2    Madelmont, J.C.3
  • 47
    • 2942615257 scopus 로고    scopus 로고
    • The anti-angiogenic basis of metronomic chemotherapy
    • Kerbel RS, Kamen BA, (2004) The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer 4: 423-436.
    • (2004) Nat Rev Cancer , vol.4 , pp. 423-436
    • Kerbel, R.S.1    Kamen, B.A.2
  • 48
    • 0038275987 scopus 로고    scopus 로고
    • The Bystander Effect
    • Hall EJ, (2003) The Bystander Effect. Health Phys 85: 5.
    • (2003) Health Phys , vol.85 , pp. 5
    • Hall, E.J.1
  • 49
    • 78449282623 scopus 로고    scopus 로고
    • Effects of irradiation on tumor cell survival, invasion and angiogenesis
    • Kargiotis O, Geka A, Rao JS, Kyritsis AP, (2010) Effects of irradiation on tumor cell survival, invasion and angiogenesis. J Neurooncol 100: 323-338.
    • (2010) J Neurooncol , vol.100 , pp. 323-338
    • Kargiotis, O.1    Geka, A.2    Rao, J.S.3    Kyritsis, A.P.4
  • 50
    • 44349184864 scopus 로고    scopus 로고
    • Etoposide Induces ATM-Dependent Mitochondrial Biogenesis through AMPK Activation
    • Fu X, Wan S, Lyu YL, Liu LF, Qi H, (2008) Etoposide Induces ATM-Dependent Mitochondrial Biogenesis through AMPK Activation. PLoS ONE 3: e2009.
    • (2008) PLoS ONE , vol.3
    • Fu, X.1    Wan, S.2    Lyu, Y.L.3    Liu, L.F.4    Qi, H.5
  • 51
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2-[Delta][Delta]CT Method
    • Livak KJ, Schmittgen TD, (2001) Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2-[Delta][Delta]CT Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.