Interaction between hydrogenase maturation factors HypA and HypB is required for [NiFe]-hydrogenase maturation

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Chan, Kwok Ho ^a   Lee, Ka Man ^a   Wong, Kam Bo ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE; HETERODIMER; LEUCINE; METALLOCHAPERONE; NICKEL; NICKEL IRON HYDROGENASE; PROTEIN HYPA; PROTEIN HYPB; UNCLASSIFIED DRUG; VALINE; CARRIER PROTEIN; ESCHERICHIA COLI PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROGENASE; HYPA PROTEIN, E COLI; HYPB PROTEIN, E COLI; NICKEL-IRON HYDROGENASE;

AMINO TERMINAL SEQUENCE; ARCHAEOGLOBUS FULGIDUS; ARTICLE; BACTERIAL STRAIN; BACTERIUM MUTANT; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME DIFFERENTIATION; ENZYME METABOLISM; ENZYME REACTIVATION; ESCHERICHIA COLI; HYDROPHOBICITY; METAL METABOLISM; NICKEL TRANSFER; NONHUMAN; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DIMERIZATION; ENZYMOLOGY; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MUTATION; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ARCHAEOGLOBUS FULGIDUS; ESCHERICHIA COLI;

AMINO ACID SEQUENCE; ARCHAEOGLOBUS FULGIDUS; BINDING SITES; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GTP-BINDING PROTEINS; HYDROGENASE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; MUTATION; NICKEL; PROTEIN STRUCTURE, TERTIARY;

EID: 84863287540     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032592     Document Type: Article

References (36)

1. Waugh R, Boxer DH, (1986) Pleiotropic hydrogenase mutants of Escherichia coli K12: growth in the presence of nickel can restore hydrogenase activity. Biochimie 68: 157-166.
2. Jacobi A, Rossmann R, Böck A, (1992) The hyp operon gene products are required for the maturation of catalytically active hydrogenase isoenzymes in Escherichia coli. Arch Microbiol 158: 444-451.
3. Maier T, Lottspeich F, Böck A, (1995) GTP hydrolysis by HypB is essential for nickel insertion into hydrogenases of Escherichia coli. Eur J Biochem 230: 133-138.
4. Olson JW, Fu CL, Maier RJ, (1997) The HypB protein from Bradyrhizobium japonicum can store nickel and is required for the nickel-dependent transcriptional regulation of hydrogenase. Mol Microbiol 24: 119-128.
5. Olson JW, Mehta NS, Maier RJ, (2001) Requirement of nickel metabolism proteins HypA and HypB for full activity of both hydrogenase and urease in Helicobacter pylori. Mol Microbiol 39: 176-182.
6. Hube M, Blokesch M, Bock A, (2002) Network of hydrogenase maturation in Escherichia coli: role of accessory proteins HypA and HybF. J Bacteriol 184: 3879-3885.
7. Hoffmann D, Gutekunst K, Klissenbauer M, Schulz-Friedrich R, Appel J, (2006) Mutagenesis of hydrogenase accessory genes of Synechocystis sp. PCC 6803. Additional homologues of hypA and hypB are not active in hydrogenase maturation. FEBS J 273: 4516-4527.
8. Böck A, King PW, Blokesch M, Posewitz MC, (2006) Maturation of hydrogenases. Adv Microb Physiol 51: 1-71.
9. Blokesch M, Böck A, (2002) Maturation of [NiFe]-hydrogenases in Escherichia coli: the HypC cycle. J Mol Biol 324: 287-296.
10. Löscher S, Zebger I, Andersen LK, Hildebrandt P, Meyer-Klaucke W, et al. (2005) The structure of the Ni-Fe site in the isolated HoxC subunit of the hydrogen-sensing hydrogenase from Ralstonia eutropha. FEBS Lett 579: 4287-4291.
11. Winter G, Buhrke T, Lenz O, Jones AK, Forgber M, et al. (2005) A model system for [NiFe] hydrogenase maturation studies: Purification of an active site-containing hydrogenase large subunit without small subunit. FEBS Lett 579: 4292-4296.
12. Paschos A, Glass RS, Böck A, (2001) Carbamoylphosphate requirement for synthesis of the active center of [NiFe]-hydrogenases. FEBS Lett 488: 9-12.
13. Paschos A, Bauer A, Zimmermann A, Zehelein E, Böck A, (2002) HypF, a carbamoyl phosphate-converting enzyme involved in [NiFe] hydrogenase maturation. J Biol Chem 277: 49945-49951.
14. Reissmann S, Hochleitner E, Wang H, Paschos A, Lottspeich F, et al. (2003) Taming of a poison: biosynthesis of the NiFe-hydrogenase cyanide ligands. Science 299: 1067-1070.
15. Blokesch M, Albracht SP, Matzanke BF, Drapal NM, Jacobi A, et al. (2004) The complex between hydrogenase-maturation proteins HypC and HypD is an intermediate in the supply of cyanide to the active site iron of [NiFe]-hydrogenases. J Mol Biol 344: 155-167.
16. Roseboom W, Blokesch M, Böck A, Albracht SP, (2005) The biosynthetic routes for carbon monoxide and cyanide in the Ni-Fe active site of hydrogenases are different. FEBS Lett 579: 469-472.
17. Forzi L, Hellwig P, Thauer RK, Sawers RG, (2007) The CO and CN(-) ligands to the active site Fe in [NiFe]-hydrogenase of Escherichia coli have different metabolic origins. FEBS Lett 581: 3317-3321.
18. Lenz O, Zebger I, Hamann J, Hildebrandt P, Friedrich B, (2007) Carbamoylphosphate serves as the source of CN(-), but not of the intrinsic CO in the active site of the regulatory [NiFe]-hydrogenase from Ralstonia eutropha. FEBS Lett 581: 3322-3326.
19. Theodoratou E, Huber R, Böck A, (2005) [NiFe]-Hydrogenase maturation endopeptidase: structure and function. Biochem Soc Trans 33: 108-111.
20. Mehta N, Olson JW, Maier RJ, (2003) Characterization of Helicobacter pylori nickel metabolism accessory proteins needed for maturation of both urease and hydrogenase. J Bacteriol 185: 726-734.
21. Atanassova A, Zamble DB, (2005) Escherichia coli HypA is a zinc metalloprotein with a weak affinity for nickel. J Bacteriol 187: 4689-4697.
22. Watanabe S, Arai T, Matsumi R, Atomi H, Imanaka T, et al. (2009) Crystal structure of HypA, a nickel-binding metallochaperone for [NiFe] hydrogenase maturation. J Mol Biol 394: 448-459.
23. Xia W, Li H, Sze KH, Sun H, (2009) Structure of a nickel chaperone, HypA, from Helicobacter pylori reveals two distinct metal binding sites. J Am Chem Soc 131: 10031-10040.
24. Leach MR, Sandal S, Sun H, Zamble DB, (2005) Metal binding activity of the Escherichia coli hydrogenase maturation factor HypB. Biochemistry 44: 12229-12238.
25. Dias AV, Mulvihill CM, Leach MR, Pickering IJ, George GN, et al. (2008) Structural and biological analysis of the metal sites of Escherichia coli hydrogenase accessory protein HypB. Biochemistry 47: 11981-11991.
26. Olson JW, Maier RJ, (2000) Dual roles of Bradyrhizobium japonicum nickelin protein in nickel storage and GTP-dependent Ni mobilization. J Bacteriol 182: 1702-1705.
27. Gasper R, Scrima A, Wittinghofer A, (2006) Structural insights into HypB, a GTP-binding protein that regulates metal binding. J Biol Chem 281: 27492-27502.
28. Xia W, Li H, Yang X, Wong KB, Sun H, (2011) Metallo-GTPase HypB from Helicobacter pylori and Its Interaction with Nickel Chaperone Protein HypA. J Biol Chem Epub.
29. Maier T, Jacobi A, Sauter M, Böck A, (1993) The Product of the HypB Gene, Which Is Required for Nickel Incorporation into Hydrogenases, Is a Novel Guanine Nucleotide-Binding Protein. J Bacteriol 175: 630-635.
30. Cai F, Ngu TT, Kaluarachchi H, Zamble DB, (2011) Relationship between the GTPase, metal-binding, and dimerization activities of E. coli HypB. J Biol Inorg Chem 16: 857-868.
31. Chan K-H, Li T, Wong C-O, Wong K-B, (2011) Structural Basis for GTP-Dependent Dimerization of Hydrogenase Maturation Factor HypB. PLoS ONE In press.
32. Ballantine SP, Boxer DH, (1985) Nickel-containing hydrogenase isoenzymes from anaerobically grown Escherichia coli K-12. J Bacteriol 163: 454-459.
33. Zhang JW, Butland G, Greenblatt JF, Emili A, Zamble DB, (2005) A role for SlyD in the Escherichia coli hydrogenase biosynthetic pathway. J Biol Chem 280: 4360-4366.
34. Baba T, Ara T, Hasegawa M, Takai Y, Okumura Y, et al. (2006) Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol Syst Biol 2: 2006 0008.
35. Schneider TD, Stephens RM, (1990) Sequence logos: a new way to display consensus sequences. Nucleic Acids Res 18: 6097-6100.
36. Crooks GE, Hon G, Chandonia JM, Brenner SE, (2004) WebLogo: a sequence logo generator. Genome Res 14: 1188-1190.