Widdrol induces apoptosis via activation of AMP-activated protein kinase in colon cancer cells

Oncology Reports

Volumn 27, Issue 5, 2012, Pages 1407-1412

  Kang, Moo Rim ^a   Park, Song Kyu ^b   Lee, Chang Woo ^a   Cho, Ig Jun ^a   Jo, Yeong Nang ^a   Yang, Jeong Wook ^a   Kim, Jin Ah ^a   Yun, Jieun ^a   Lee, Ki Hoon ^a   Kwon, Hyun Ju ^c   Kim, Byung Woo ^c   Lee, Kiho ^b   Kang, Jong Soon ^a   Kim, Hwan Mook ^d  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea University   (South Korea)

^c Dong Eui University   (South Korea)

^d Gachon University College of Medicine   (South Korea)

Author keywords

AMP activated protein kinase; Apoptosis; Colon cancer; Widdrol

Indexed keywords

CASPASE 3; CASPASE 7; CASPASE 9; DOXORUBICIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN KINASE INHIBITOR; SESQUITERPENE DERIVATIVE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WIDDROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; JUNIPERUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; TIME; TUMOR VOLUME; TUMOR XENOGRAFT; WEIGHT REDUCTION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BENZOCYCLOHEPTENES; CASPASES; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; COLONIC NEOPLASMS; ENZYME ACTIVATION; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; PHOSPHORYLATION; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84863286988     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1644     Document Type: Article

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