Aqueous extract of Paeonia suffruticosa inhibits migration and metastasis of renal cell carcinoma cells via suppressing VEGFR-3 pathway

Evidence-based Complementary and Alternative Medicine

Volumn 2012, Issue , 2012, Pages

  Wang, Shih Chin ^a   Tang, Sai Wen ^a   Lam, Sio Hong ^a   Wang, Chung Chieh ^b   Liu, Yu Huei ^a,c,d   Lin, Hsuan Yuan ^a   Lee, Shoei Sheng ^a   Lin, Jung Yaw ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ABRUS PRECATORIUS EXTRACT; ANDROGRAPHIS PANICULATA EXTRACT; ANTINEOPLASTIC AGENT; CATHARANTHUS ROSEUS EXTRACT; CURCUMA ZEDOARIA EXTRACT; F ACTIN; FOCAL ADHESION KINASE; G ACTIN; HERBACEOUS AGENT; KALIMERIS INDICA EXTRACT; PAEONIA SUFFRUTICOSA EXTRACT; PLANT EXTRACT; PLATYCODON GRANDIFLORUM EXTRACT; RAC1 PROTEIN; SAN JHONG KUEI JIAN TANG; TARAXACUM MONOGOLICUM EXTRACT; TRICHOSANTHES KIRILOWII EXTRACT; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 3;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; CARCINOMA CELL; CELL MIGRATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY CARCINOMA; METASTASIS INHIBITION; MOUSE; NONHUMAN; PAEONIA SUFFRUTICOSA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 84863266188     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2012/409823     Document Type: Article

References (46)

1. Markman M., Safety issues in using complementary and alternative medicine Journal of Clinical Oncology 2002 20 18 39S 41S
2. Cui Y., Shu X. O., Gao Y., Wen W., Ruan Z. X., Jin F., Zheng W., Use of complementary and alternative medicine by Chinese women with breast cancer Breast Cancer Research and Treatment 2004 85 3 263 270 (Pubitemid 38987261)
3. Richardson M. A., Sanders T., Palmer J. L., Greisinger A., Singletary S. E., Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology Journal of Clinical Oncology 2000 18 13 2505 2514 (Pubitemid 30432515)
4. Lin H. C., Ding H. Y., Wu Y. C., Two novel compounds from Paeonia suffruticosa Journal of Natural Products 1998 61 3 343 346
5. Hsieh C. L., Cheng C. Y., Tsai T. H., Lin I. H., Liu C. H., Chiang S. Y., Lin J. G., Lao C. J., Tang N. Y., Paeonol reduced cerebral infarction involving the superoxide anion and microglia activation in ischemia-reperfusion injured rats Journal of Ethnopharmacology 2006 106 2 208 215
6. Li Y., Zhang W., Huang L., Shi J., Pharmacological of cortex moutan and core Zhongguo Zhong Yao Za Zhi 1997 22 4 214 254
7. Oh G. S., Pae H. O., Oh H., Hong S. G., Kim I. K., Chai K. Y., Yun Y. G., Kwon T. O., Chung H. T., In vitro anti-proliferative effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on human hepatocellular carcinoma cell line, SK-HEP-1 cells Cancer Letters 2001 174 1 17 24 (Pubitemid 33001304)
8. Sheehan M. P., Atherton D. J., One-year follow up of children treated with Chinese medicinal herbs for atopic eczema British Journal of Dermatology 1994 130 4 488 493 (Pubitemid 24204669)
9. Okubo T., Nagai F., Seto T., Satoh K., Ushiyama K., Kano I., The inhibition of phenylhydroquinone-induced oxidative DNA cleavage by constituents of Moutan Cortex and Paeoniae Radix Biological and Pharmaceutical Bulletin 2000 23 2 199 203 (Pubitemid 30136979)
10. Lau C. H., Chan C. M., Chan Y. W., Lau K. M., Lau T. W., Lam F. C., Law W. T., Che C. T., Leung P. C., Fung K. P., Ho Y. Y., Lau C. B. S., Pharmacological investigations of the anti-diabetic effect of Cortex Moutan and its active component paeonol Phytomedicine 2007 14 11 778 784 (Pubitemid 47554505)
11. Sun G. P., Wan X., Xu S. P., Wang H., Liu S. H., Wang Z. G., Antiproliferation and apoptosis induction of paeonol in human esophageal cancer cell lines Diseases of the Esophagus 2008 21 8 723 729
12. Sun Y., Dong Y., Jiang H. J., Cai T. T., Chen L., Zhou X., Chen T., Xu Q., Dissection of the role of paeoniflorin in the traditional Chinese medicinal formula Si-Ni-San against contact dermatitis in mice Life Sciences 2009 84 11-12 337 344
13. Xu S. P., Sun G. P., Shen Y. X., Wei W., Peng W. R., Wang H., Antiproliferation and apoptosis induction of paenol in HepG2 cells World Journal of Gastroenterology 2007 13 2 250 256 (Pubitemid 46231328)
14. Hung J. Y., Yang C. J., Tsai Y. M., Huang H. W., Huang M. S., Antiproliferative activity of paeoniflorin is through cell cycle arrest and the Fas/Fas ligand-mediated apoptotic pathway in human non-small cell lung cancer A549 cells Clinical and Experimental Pharmacology and Physiology 2008 35 2 141 147
15. Pantuck A. J., Zisman A., Belldegrun A., The changing natural history of renal cell carcinoma Journal of Urology 2001 166 1611 1623
16. Russo P., Renal cell carcinoma: presentation, staging, and surgical treatment Seminars in Oncology 2000 27 2 160 176 (Pubitemid 30205371)
17. Pavlovich C. P., Schmidt L. S., Searching for the hereditary causes of renal-cell carcinoma Nature Reviews Cancer 2004 4 5 381 393 (Pubitemid 38579484)
18. Cheville J. C., Lohse C. M., Zincke H., Weaver A. L., Blute M. L., Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma American Journal of Surgical Pathology 2003 27 5 612 624 (Pubitemid 36514472)
19. Amato R. J., Chemotherapy for renal cell carcinoma Seminars in Oncology 2000 27 2 177 186 (Pubitemid 30205372)
20. Lane B. R., Rini B. I., Novick A. C., Campbell S. C., Targeted molecular therapy for renal cell carcinoma Urology 2007 69 1 3 10 (Pubitemid 46161691)
21. Van Spronsen D. J., De Weijer K. J. M., Mulders P. F. A., De Mulder P. H. M., Novel treatment strategies in clear-cell metastatic renal cell carcinoma Anti-Cancer Drugs 2005 16 7 709 717 (Pubitemid 41104919)
22. Ishimura T., Sakai I., Hara I., Eto H., Miyake H., Microscopic venous invasion in renal cell carcinoma as a predictor of recurrence after radical surgery International Journal of Urology 2004 11 5 264 268 (Pubitemid 38758140)
23. Ernstoff M. S., Crocenzi T. S., Seigne J. D., Crosby N. A., Cole B. F., Fisher J. L., Uhlenhake J. C., Mellinger D., Foster C., Farnham C. J., Mackay K., Szczepiorkowski Z. M., Webber S. M., Schned A. R., Harris R. D., Barth R. J., Heaney J. A., Noelle R. J., Developing a rational tumor vaccine therapy for renal cell carcinoma: immune Yin and Yang Clinical Cancer Research 2007 13 2 733ss 740s
24. Glaspy J. A., Therapeutic options in the management of renal cell carcinoma Seminars in Oncology 2002 29 3 41 46 (Pubitemid 34620435)
25. Corey E., Brown L. G., Quinn J. E., Poot M., Roudier M. P., Higano C. S., Vessella R. L., Zoledronic acid exhibits inhibitory effects on osteoblastic and osteolytic metastases of prostate cancer Clinical Cancer Research 2003 9 1 295 306 (Pubitemid 36109746)
26. Chen G., Raman P., Bhonagiri P., Strawbridge A. B., Pattar G. R., Elmendorf J. S., Protective effect of phosphatidylinositol 4,5-bisphosphate against cortical filamentous actin loss and insulin resistance induced by sustained exposure of 3T3-L1 adipocytes to insulin Journal of Biological Chemistry 2004 279 38 39705 39709 (Pubitemid 39258239)
27. Cross M. J., Dixelius J., Matsumoto T., Claesson-Welsh L., VEGF-receptor signal transduction Trends in Biochemical Sciences 2003 28 9 488 494 (Pubitemid 38340413)
28. Garces C. A., Kurenova E. V., Golubovskaya V. M., Cance W. G., Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells Cancer Research 2006 66 3 1446 1454 (Pubitemid 43259925)
29. Choma D. P., Milano V., Pumiglia K. M., DiPersio C. M., Integrin 3 1-dependent activation of FAK/Src regulates Rac1-mediated keratinocyte polarization on laminin-5 Journal of Investigative Dermatology 2007 127 1 31 40 (Pubitemid 46005658)
30. Heasman S. J., Ridley A. J., Mammalian Rho GTPases: new insights into their functions from in vivo studies Nature Reviews Molecular Cell Biology 2008 9 9 690 701
31. Vignjevic D., Montagnac G., Reorganisation of the dendritic actin network during cancer cell migration and invasion Seminars in Cancer Biology 2008 18 1 12 22 (Pubitemid 350266367)
32. Cha Y. Y., Lee E. O., Lee H. J., Park Y. D., Ko S. G., Kim D. H., Kim H. M., Kang I. C., Kim S. H., Methylene chloride fraction of Scutellaria barbata induces apoptosis in human U937 leukemia cells via the mitochondrial signaling pathway Clinica Chimica Acta 2004 348 1-2 41 48
33. Chen Q., Peng W., Qi S., Xu A., Apoptosis of human highly metastatic lung cancer cell line 95-D induced by acutiaporberine, a novel bisalkaloid derived from Thalictrum acutifolium Planta Medica 2002 68 6 550 553 (Pubitemid 34774755)
34. Hsieh T. C., Lu X., Guo J., Xiong W., Kunicki J., Darzynkiewicz Z., Wu J. M., Effects of herbal preparation Equiguard on hormone-responsive and hormone-refractory prostate carcinoma cells: mechanistic studies International Journal of Oncology 2002 20 4 681 689
35. Lin S. Y., Liu J. D., Chang H. C., Yeh S. D., Lin C. H., Lee W. S., Magnolol suppresses proliferation of cultured human colon and liver cancer cells by inhibiting DNA synthesis and activating apoptosis Journal of Cellular Biochemistry 2002 84 3 532 544
36. Ma J., Fu N. Y., Pang D. B., Wu W. Y., Xu A. L., Apoptosis induced by isoliquiritigenin in human gastric cancer MGC-803 cells Planta Medica 2001 67 8 754 757 (Pubitemid 33044487)
37. Wan X. A., Sun G. P., Wang H., Xu S. P., Wang Z. G., Liu S. H., Synergistic effect of paeonol and cisplatin on oesophageal cancer cell lines Digestive and Liver Disease 2008 40 7 531 539
38. Su J. L., Yen C. J., Chen P. S., Chuang S. E., Hong C. C., Kuo I. H., Chen H. Y., Hung M. C., Kuo M. L., The role of the VEGF-C/VEGFR-3 axis in cancer progression British Journal of Cancer 2007 96 4 541 545
39. Wang Y., Nakayama M., Pitulescu M. E., Schmidt T. S., Bochenek M. L., Sakakibara A., Adams S., Davy A., Deutsch U., Lthi U., Barberis A., Benjamin L. E., Mkinen T., Nobes C. D., Adams R. H., Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis Nature 2010 465 7297 483 486
40. Bando H., Brokelmann M., Toi M., Alitalo K., Sleeman J. P., Sipos B., Grne H. J., Weich H. A., Immunodetection and quantification of vascular endothelial growth factor receptor-3 in human malignant tumor tissues International Journal of Cancer 2004 111 2 184 191 (Pubitemid 38924694)
41. Lian Z., Liu J., Wu M., Wang H. Y., Arbuthnot P., Kew M., Feitelson M. A., Hepatitis B x antigen up-regulates vascular endothelial growth factor receptor 3 in hepatocarcinogenesis Hepatology 2007 45 6 1390 1399 (Pubitemid 46918323)
42. Dhar D. K., Naora H., Yamanoi A., Ono T., Kohno H., Otani H., Nagasue N., Requisite role of VEGF receptors in angiogenesis of hepatocellular carcinoma: a comparison with angiopoietin/Tie pathway Anticancer Research 2002 22 1 A 379 386 (Pubitemid 34475326)
43. Salameh A., Galvagni F., Bardelli M., Bussolino F., Oliviero S., Direct recruitment of CRK and GRB2 to VEGFR-3 induces proliferation, migration, and survival of endothelial cells through the activation of ERK, AKT, and JNK pathways Blood 2005 106 10 3423 3431 (Pubitemid 41609177)
44. Besson A., Assoian R. K., Roberts J. M., Regulation of the cytoskeleton: an oncogenic function for CDK inhibitors? Nature Reviews Cancer 2004 4 12 948 955 (Pubitemid 39626218)
45. Ridley A. J., Schwartz M. A., Burridge K., Firtel R. A., Ginsberg M. H., Borisy G., Parsons J. T., Horwitz A. R., Cell migration: integrating signals from front to back Science 2003 302 5651 1704 1709 (Pubitemid 37505725)
46. Hall A., Rho GTpases and the actin cytoskeleton Science 1998 279 5350 509 514 (Pubitemid 28067271)