A diastereoselective, nucleophile-promoted aldol-lactonization of ketoacids leading to bicyclic-β-lactones

Journal of Organic Chemistry

Volumn 77, Issue 5, 2012, Pages 2496-2500

  Liu, Gang ^a   Shirley, Morgan E ^a   Romo, Daniel ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4-DIMETHYLAMINOPYRIDINE; ACID ACTIVATION; DIASTEREO-SELECTIVITY; DIASTEREOSELECTIVE; KETOACIDS; LEWIS BASE;

CARBOXYLIC ACIDS; CHLORINE COMPOUNDS;

STEREOSELECTIVITY;

4 DIMETHYLAMINOPYRIDINE; CARBOXYLIC ACID; DICHLOROMETHANE; LACTONE DERIVATIVE; LEWIS BASE; NUCLEOPHILE; OXOACID; TOLUENESULFONAMIDE DERIVATIVE;

ALDOL REACTION; ARTICLE; CATALYST; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; CYCLIZATION; ELECTROPHILICITY; EPIMERIZATION; LACTONIZATION; NONHUMAN; NUCLEOPHILICITY; OZONOLYSIS; REACTION TIME; SCALE UP; STEREOCHEMISTRY; STOICHIOMETRY;

BICYCLO COMPOUNDS; CYCLIZATION; KETO ACIDS; KETONES; LACTONES; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 84863256759     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo202252y     Document Type: Article

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