A synthesis of the hypocholesterolemic agent 1233A via asymmetric [2 + 2] cycloaddition

Synthesis

Volumn , Issue 11, 1998, Pages 1655-1661

  Dymock, B W ^a   Kocienski, P J ^a   Pons, J M ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Carboxylation; Chiral Lewis acid; Coupling; Diene synthesis; Pfaltz reduction; 2+2 cycloaddition; lactone

Indexed keywords

12 HYDROXY 13 HYDROXYMETHYL 3,5,7 TRIMETHYLTETRADECA 2,4 DIENEDIOIC ACID 12,14 LACTONE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; HYPOCHOLESTEROLEMIC AGENT; MEVINOLIN;

ARTICLE; CARBOXYLATION; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0031797843     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-2194     Document Type: Article

References (42)