Inhibition of copper uptake in yeast reveals the copper transporter Ctr1p as a potential molecular target of saxitoxin

Environmental Science and Technology

Volumn 46, Issue 5, 2012, Pages 2959-2966

  Cusick, Kathleen D ^a   Minkin, Steven C ^a   Dodani, Sheel C ^b   Chang, Christopher J ^b   Wilhelm, Steven W ^a   Sayler, Gary S ^a,c  

^a UNIVERSITY OF TENNESSEE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUATIC COMMUNITIES; COPPER UPTAKE; EXTRACELLULAR; FLUORESCENT PROBES; IRON HOMEOSTASIS; IRON UPTAKE; MICROARRAY ANALYSIS; MICROBIAL CELLS; MOLECULAR TARGETS; MULTICOPPER OXIDASE; POTASSIUM CHANNELS; PROTEIN EXPRESSIONS; PROTEIN PROFILES; SECONDARY METABOLITES;

CHELATION; ENZYME ACTIVITY; GENES; IRON; MOLECULAR PHYSICS; PHYSIOLOGICAL MODELS; PHYSIOLOGY; POTASSIUM; SODIUM; YEAST;

COPPER;

2,9 DIMETHYL 1,10 PHENANTHROLINE; BATHOCUPROINEDISULFONATE; CHELATING AGENT; COPPER; FLUORESCENT DYE; IRON; MENKES PROTEIN; SAXITOXIN; UNCLASSIFIED DRUG;

BIOLOGICAL UPTAKE; COPPER; EVOLUTIONARY BIOLOGY; GENE EXPRESSION; HOMEOSTASIS; INHIBITION; IRON; MOLECULAR ANALYSIS; PHYSIOLOGY; PLANKTON; PROTEIN; SECONDARY METABOLITE; TOXIN; YEAST;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE; SENSOR; TARGET CELL; TRANSCRIPTION REGULATION; YEAST CELL;

BIOLOGICAL TRANSPORT; CATION TRANSPORT PROTEINS; COPPER; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; GREEN FLUORESCENT PROTEINS; HOMEOSTASIS; INTRACELLULAR SPACE; IRON; MODELS, BIOLOGICAL; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SAXITOXIN;

CYANOBACTERIA; DINOPHYCEAE; VERTEBRATA;

EID: 84863249064     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es204027m     Document Type: Article

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