Regulation of fertilization in male rats by CatSper2 knockdown

Asian Journal of Andrology

Volumn 14, Issue 2, 2012, Pages 301-309

  Zhang, Zhen ^a   Wang, Gen Lin ^a   Li, Hui Xia ^a   Li, Lian ^a   Cui, Qun Wei ^a   Wei, Cheng Bin ^b   Zhou, Fei ^c  

^a NANJING AGRICULTURAL UNIVERSITY   (China)

^b INSTITUTE OF PLANT PROTECTION   (China)

^c NANJING UNIVERSITY   (China)

Author keywords

Catsper2; in vivo electroporation; male contraception; rete testis microinjection

Indexed keywords

CYCLIC AMP; ION CHANNEL; PLASMID DNA; PROTEIN CATSPER2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CELL ACTIVITY; CELL MIGRATION; CELL MOTILITY; CELL VIABILITY; CONTROLLED STUDY; ELECTROPORATION; EPIDIDYMIS; FEASIBILITY STUDY; FEMALE; GENE EXPRESSION; GENE SILENCING; HISTOLOGY; MALE; NONHUMAN; RAT; SIGNAL TRANSDUCTION; SPERM; SPERMATOGENESIS; VISCOELASTICITY;

ANIMALS; CALCIUM CHANNELS; CELL SURVIVAL; FERTILITY; FERTILIZATION; GENE KNOCKDOWN TECHNIQUES; MALE; MODELS, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; SEMINAL PLASMA PROTEINS; SIGNAL TRANSDUCTION; SPERM MOTILITY; TESTIS;

EID: 84863230912     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1038/aja.2011.118     Document Type: Article

References (53)

1. Anderson RA, Baird DT. Male contraception. Endocr Rev 2002; 23: 735-62. (Pubitemid 36001999)
2. Kamischke A, Nieschlag E. Progress towards hormonal male contraception. Trends Pharmacol Sci 2004; 25: 49-57. (Pubitemid 38076956)
3. WHO Task Force on Methods for the Regulation of Male Fertility. Contraceptive efficacy of testosterone-induced azoospermia in normal men. Lancet 1990; 336: 955-9.
4. Lopez LM, Grimes DA, Schulz KF. Nonhormonal drugs for contraception in men: a systematic review. Obstetr Gynecol Surv 2005; 60: 746-52. (Pubitemid 41546459)
5. Delves PJ, Lund T, Roitt IM. Antifertility vaccines. Trends Immunol 2002; 23: 213-9. (Pubitemid 34260938)
6. Jones AR, Cooper TG. A re-appraisal of the post-testicular action and toxicity of chlorinated antifertility compounds. Int J Androl 1999; 22: 130-8. (Pubitemid 29253592)
7. Dan J. Studies on the acrosome. III. Effect of calcium deficiency. Biol Bull 1954; 107: 335-49.
8. Bredderman PJ, Foote RH, Hansel W. The effect of calcium ions on cell volume and motility of bovine spermatozoa. Proc Soc Exp Biol Med 1971; 137: 1440-3.
9. Yanagimachi R, Usui N. Calcium dependence of the acrosome reaction and activation of guinea pig spermatozoa. Exp Cell Res 1974; 89: 161-74.
10. Young LG, Nelson L. Calcium ions and control of the motility of sea urchin spermatozoa. J Reprod Fertil 1974; 41: 371-8.
11. Ren D, Navarro B, Perez G, Jackson AC, Hsu S et al. A sperm ion channel required for sperm motility and male fertility. Nature 2001; 413: 603-9. (Pubitemid 32964054)
12. Shi YL, Bai JP, Wang WP. Ion-channels in human sperm membrane and contraceptive mechanisms of male antifertility compounds derived from Chinese traditional medicine. Acta Pharmacol Sin 2003; 24: 22-30.
13. Quill TA, Sugden SA, Rossi KL, Doolittle LK, Hammer RE et al. Hyperactivated sperm motility driven by CatSper2 is required for fertilization. Proc Natl Acad Sci USA 2003; 100: 14869-74. (Pubitemid 37517983)
14. Qi H, Moran MM, Navarro B, Chong JA, Krapivinsky G et al. All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility. Proc Natl Acad Sci USA 2007; 104: 1219-23. (Pubitemid 46183985)
15. Carlson AE, Westenbroek RE, Quill T, Ren D, Clapham DE et al. CatSper1 required for evoked Ca21+ entry and control of flagellar function in sperm. Proc Natl Acad Sci USA 2003; 100: 14864-8. (Pubitemid 37517982)
16. Quill TA, Ren D, Clapham DE, Garbers DL. A voltage-gated ion channel expressed specifically in spermatozoa. Proc Natl Acad Sci USA 2001; 98: 12527-31. (Pubitemid 33019979)
17. Jin JL, O'Doherty AM, Wang S, Zheng H, Sanders KM et al. Catsper3 and Catsper4 encode two cation channel-like proteins exclusively expressed in the testis. Biol Reprod 2005; 73: 1235-42. (Pubitemid 41698614)
18. Marquez B, Ignotz G, Suarez SS. Contributions of extracellular and intracellular Ca21+ to regulation of sperm motility: release of intracellular stores can hyperactivate CatSper1 and CatSper2 null sperm. Dev Biol 2007; 303: 214-21. (Pubitemid 46241100)
19. Li HG, Liao AH, Ding XF, Zhou H, Xiong CL. The expression and significance of CATSPER1 in human testis and ejaculated spermatozoa. Asian J Androl 2006; 8:301-6.
20. Neumann E, Schaefer-Ridder M, Wang Y, Hofschneider PH. Gene transfer into mouse lyoma cells by electroporation in high electric fields. EMBO J 1982; 1: 841-5.
21. Brunner S, Furtbauer E, Sauer T, Kursa M, Wagner E. Overcoming the nuclear barrier. Cell cycle independent nonviral gene transfer with linear polyethylenimine or electroporation. Mol Ther 2002; 5: 80-6. (Pubitemid 34110484)
22. St George JA. Gene therapy progress and prospects: adenoviral vectors. Gene Ther 2003; 10: 1135-41. (Pubitemid 36896588)
23. Muramatsu T, Shibata O, Ryoki S, Ohmori Y, Okumura J. Foreign gene expression in the mouse testis by localized in vivo gene transfer. Biochem Biophys Res Commun 1997; 233: 45-9. (Pubitemid 27215906)
24. Yamazaki Y, Fujimoto H, Ando H, Ohyama T, Hirota Y et al. In vivo gene transfer to mouse spermatogenic cells by deoxyribonucleic acid injection into seminiferous tubules and subsequent electroporation. Biol Reprod 1998; 59: 1439-44.
25. Huang Z, Tamura M, Sakurai T, Chuma S, Saito T et al. In vivo transfection of testicular germ cells and transgenesis by using the mitochondrially localized jellyfish fluorescent protein gene. FEBS Lett 2000; 487: 248-51. (Pubitemid 32057120)
26. Yamazaki Y, Yagi T, Ozaki T, Imoto K. In vivo gene transfer to mouse spermatogenic cells using green fluorescent protein as a marker. J Exp Zool 2000; 286: 212-8. (Pubitemid 30049423)
27. Ike A, Ohta H, Onishi M, Iguchi N, Nishimune Y et al. Transient expression analysis of the mouse ornithine decarboxylase antizyme haploid-specific promoter using in vivo electroporation. FEBS Lett 2004; 559: 159-64. (Pubitemid 38186721)
28. Kubota H, Hayashi Y, Kubota Y, Coward K, Parrington J. Comparison of two methods of in vivo gene transfer by electroporation. Fertil Steril 2005; 83: 1310-8. (Pubitemid 40543518)
29. Mruk DD. New perspectives in non-hormonal male contraception. Trends Endocrinol Metab 2008; 19: 57-64. (Pubitemid 351317896)
30. Zhang Z, Zhou X, Li HX, Cui QW, Yu J et al. Delivery of CatSper2 siRNA into rats sperms by electroporation repressed Ca21 influx during sperm hyperactivation. Agric Sci China (Engl) 2011; 10: 101-5.
31. Brinster RL, Avarbock MR. Germline transmission of donor haplotype following spermatogonial transplantation. Proc Natl Acad Sci USA 1994; 91: 11303-7. (Pubitemid 24356332)
32. Bers DM, Patton CW, Nuccitellid R. A practical guide to the preparation of Ca21+ buffers. Methods Cell Biol 1994; 40: 3-29.
33. Ho HC, Suarez SS. An inositol 1,4,5-trisphosphate receptor-gated intracellular Ca21+ store is involved in regulating sperm hyperactivated motility. Biol Reprod 2001; 65: 1606-15. (Pubitemid 33031523)
34. Grynkiewicz G, Poenie M, Tsien RY. A new generation of Ca21+ indicators with greatly improved fluorescence properties. J Biol Chem 1985; 260: 3440-50. (Pubitemid 15114340)
35. Holloway AJ, Moore HD, Foster PM. The use of rat in vitro fertilization to detect reductions in the fertility of spermatozoa from males exposed to ethylene glycol monomethyl ether. Reprod Toxicol 1990; 4: 21-7.
36. Holloway AJ, Moore HD, Foster PM. The use of in vitro fertilization to detect reductions in the fertility of male rats exposed to 1,3-dinitrobenzene. Fundam Appl Toxicol 1990; 14: 113-22. (Pubitemid 20097361)
37. Fraser LR. In vitro capacitation and fertilization. Methods Enzymol 1993; 225: 239-53. (Pubitemid 23301525)
38. Moore HD. In vitro manipulation of gametes and embryos for evaluating the effect of chemicals on germ cell function and developmental potential. Food Chem Toxicol 1986; 24: 607-13. (Pubitemid 17184020)
39. Byrd W, Tsu J, Wolf DP. Kinetics of spontaneous and induced acrosomal loss in human sperm incubated under capacitating and noncapacitating conditions. Gamete Res 1989; 22: 109-22. (Pubitemid 19202190)
40. Marquez B, Suarez SS. Different signaling pathways in bovine sperm regulate capacitationand hyperactivation. Biol Reprod 2004; 70: 1626-33. (Pubitemid 38715617)
41. Umemoto Y, Sasaki S, Kojima Y, Kubota H, Kaneko T et al. Gene transfer to mouse testes by electroporation and its influence on spermatogenesis. J Androl 2005; 26: 264-71. (Pubitemid 40293713)
42. Dhup S, Majumdar SS. Transgenesis via permanent integration of genes in repopulating spermatogonial cells in vivo. Nat Methods 2008; 5: 601-3. (Pubitemid 351911863)
43. Niu Y, Liang S. Progress in gene transfer by germ cells in mammals. J Genet Genom 2008; 35: 701-14.
44. Lishko PV, Botchkina IL, Kirichok Y. Progesterone activates the principal Ca21+ channel of human sperm. Nature 2011; 471: 387-91.
45. Strunker T, Goodwin N, Brenker C, Kashikar ND, Weyand I et al. The CatSper channel mediates progesterone-induced Ca21 influx in human sperm. Nature 2011; 471: 382-6.
46. Barratt CL. The mystery is solved-CatSper is the principal calcium channel activated by progesterone in human spermatozoa. Asian J Androl 2011; 13: 351-2.
47. Benoff S , Cooper GW , Hurley I , Mandel FS , Rosenfeld DL et al. The effect of calcium ion channel blockers on sperm fertilization potential. Fertil Steril 1994; 62: 606-17. (Pubitemid 24273213)
48. Ho HC, Granish KA, Suarez SS. Hyperactivated motility of bull sperm is triggered at the axoneme by Ca21 and Not cAMP. Dev Biol 2002; 250: 208-17.
49. Yanagimachi R. Requirement of extracellular calcium ions for various stages of fertilization and fertilization-related phenomena in the hamster. Gamete Res 1982; 5: 323-44. (Pubitemid 12030243)
50. Suárez SS, Osman RA. Initiation of hyperactivated flagellar bending in mouse sperm within the female reproductive tract. Biol Reprod 1987; 36: 1191-8.
51. Suarez SS, Dai X. Intracellular calcium reaches different levels of elevation in hyperactivated and acrosome-reacted hamster sperm. Mol Reprod Dev 1995; 42: 325-33.
52. Ho HC, Suarez SS. Characterization of the intracellular calcium store at the base of the sperm flagellum that regulates hyperactivated motility. Biol Reprod 2003; 68: 1590-6. (Pubitemid 36519762)
53. Suarez SS, Dai X. Hyperactivation enhances mouse sperm capacity for penetrating viscoelastic media. Biol Reprod 1992; 46: 686-91.