Daldinan A, a novel isoindolinone antioxidant from the ascomycete Daldinia concentrica

Journal of Antibiotics

Volumn 65, Issue 2, 2012, Pages 95-97

  Lee, In Kyoung ^a   Kim, Seong Eun ^a   Yeom, Ji Hee ^a   Ki, Dae Won ^a   Lee, Myeong Seok ^a   Song, Ja Gyeong ^a   Kim, Young Sook ^a   Seok, Soon Ja ^b   Yun, Bong Sik ^a  

^a Chonbuk National University   (South Korea)

^b National Institute of Animal Science   (South Korea)

Author keywords

antioxidant; daldinan A; Daldinia concentrica; mushroom

Indexed keywords

ANTIOXIDANT; DALDINAN A; INDOLE DERIVATIVE; TROLOX C; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; ASCOMYCETES; CARBON NUCLEAR MAGNETIC RESONANCE; DALDINIA CONCENTRICA; DRUG STRUCTURE; FRUITING BODY; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTIOXIDANTS; FREE RADICAL SCAVENGERS; HETEROCYCLIC COMPOUNDS, 3-RING; INDOLES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; XYLARIALES;

BASIDIOMYCOTA; DALDINIA CONCENTRICA;

EID: 84863229667     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2011.109     Document Type: Article

References (13)

1. Golbidi, S., Ebadi, S. A. & Laher, I. Antioxidants in the treatment of diabetes. Curr. Diabetes Rev. 7, 106-125 (2011).
2. Cuzzocrea, S., Riley, D. P., Caputi, A. P. & Salvemini, D. Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharmacol. Rev. 53, 135-159 (2001). (Pubitemid 32173112)
3. Margaill, I., Plotkine, M. & Lerouet, D. Antioxidant strategies in the treatment of stroke. Free Radic. Biol. Med. 39, 429-443 (2005). (Pubitemid 41021642)
4. Jang, Y.-W. et al. Chemical constituents of the fruiting body of Xylaria polymorpha. Mycobiology 37, 207-210 (2009).
5. Hashimoto, T., Tahara, S., Takaoka, S., Tori, M. & Asakawa, Y. Structures of daldinins AC, three novel azaphilone derivatives from ascomycetous fungus Daldinia concentrica. Chem. Pharm. Bull. 42, 2397-2399 (1994). (Pubitemid 24363327)
6. Lee, I.-K., Seok, S.-J., Kim, W.-G. & Yun, B.-S. Diaporthin and orthosporin from the fruiting body of Daldinia concentrica. Mycobiology 34, 38-40 (2006).
7. Qin, X.-D. et al. Concentricolide, an anti-HIV agent from the ascomycete Daldinia concentrica. Helv. Chim. Acta 89, 127-133 (2006). (Pubitemid 43145542)
8. Quang, D. N., Hashimoto, T., Tanaka, M., Baumgartner, M. & Stadler, M. et al. Concentriols B, C and D, three squalene-type triterpenoids from the ascomycete Daldinia concentrica. Phytochemistry 61, 345-353 (2002). (Pubitemid 35176035)
9. Qin, X.-D. & Liu, J.-K. Natural aromatic steroids as potential molecular fossils from the fruiting bodies of the ascomycete Daldinia concentrica. J. Nat. Prod. 67, 2133-2135 (2004). (Pubitemid 40092576)
10. Quang, D. N., Hashimoto, T., Tanaka, M., Baumgartner, M. & Stadler, M. et al. Chemical constituents of the ascomycete Daldinia concentrica. J. Nat. Prod. 65, 1869-1874 (2002). (Pubitemid 36055439)
11. Lee, I.-K., Yun, B.-S., Kim, Y.-H. & Yoo, I.-D. Two neuroprotective compounds from mushroom Daldinia concentrica. J. Microbiol. Biotechnol. 12, 692-694 (2002).
12. Lee, I. K., Jung, J. Y., Kim, Y. S., Rhee, M. H. & Yun, B. S. p-Terphenyls from the fruiting bodies of Paxillus curtisii and their antioxidant properties. Bioorg. Med. Chem. 17, 4674-4680 (2009).
13. Ferreira, I. C., Baptista, P., Vilas-Boas, M. & Barros, L. Free-radical scavenging capacity and reducing power of wild edible mushrooms from northeast Portugal: Individual cap and stipe activity. Food Chem. 100, 1511-1516 (2007). (Pubitemid 44142873)