Abbott Physicochemical Tiering (APT) - A unified approach to HTS triage

Bioorganic and Medicinal Chemistry

Volumn 20, Issue 14, 2012, Pages 4564-4573

  Cox, Philip B ^a   Gregg, Robert J ^a   Vasudevan, Anil ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

HTS (high throughput screening); Physicochemical properties; Tiering

Indexed keywords

G PROTEIN COUPLED RECEPTOR; PHOSPHOTRANSFERASE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CORRELATIONAL STUDY; HIGH THROUGHPUT SCREENING; HYDROGEN BOND; LIPOPHILICITY; MEDICAL RESEARCH; MOLECULAR WEIGHT; PERFORMANCE MEASUREMENT SYSTEM; PERMEABILITY; PHYSICAL CHEMISTRY; POLARIZATION; PROCESS OPTIMIZATION; PROTEIN TARGETING; PUBLICATION; SOLUBILITY; SURFACE PROPERTY; VALIDATION STUDY;

DRUG EVALUATION, PRECLINICAL; DRUG INDUSTRY; HIGH-THROUGHPUT SCREENING ASSAYS;

EID: 84863216438     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2012.05.047     Document Type: Article

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