Mg-Zr-Sr alloys as biodegradable implant materials

Acta Biomaterialia

Volumn 8, Issue 8, 2012, Pages 3177-3188

  Li, Yuncang ^a   Wen, Cuie ^b   Mushahary, Dolly ^c   Sravanthi, Ragamouni ^c   Harishankar, Nemani ^d   Pande, Gopal ^c   Hodgson, Peter ^a  

^a DEAKIN UNIVERSITY   (Australia)

^b SWINBURNE UNIVERSITY OF TECHNOLOGY   (Australia)

^c CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^d NATIONAL INSTITUTE OF NUTRITION   (India)

Author keywords

Biocompatibility; Biodegradation; Bone regeneration; Mechanical properties; Mg Zr Sr alloys

Indexed keywords

ALLOYING ELEMENTS; BINARY ALLOYS; BIOCOMPATIBILITY; BIODEGRADABILITY; BIODEGRADATION; BONE; COMPRESSIVE STRENGTH; CORROSION RESISTANCE; CORROSION RESISTANT ALLOYS; GRAIN BOUNDARIES; MAGNESIUM ALLOYS; X RAY DIFFRACTION; ZIRCONIUM ALLOYS;

BIODEGRADABLE IMPLANTS; BONE FORMATION; BONE REGENERATION; IMPLANT MATERIALS; IN-VITRO; IN-VIVO; MECHANICAL; MG ALLOY; MG-SR MASTER ALLOY; VITRO BIOCOMPATIBILITIES;

TERNARY ALLOYS;

ALLOY; BIOMATERIAL; HYDROGEN; MAGNESIUM; STRONTIUM; ZIRCONIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; BIODEGRADABLE IMPLANT; COMPRESSIVE STRENGTH; CONTROLLED STUDY; CORROSION; ELECTROCHEMICAL ANALYSIS; HEMOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROSCOPY; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; RABBIT; X RAY DIFFRACTION;

ORYCTOLAGUS CUNICULUS;

EID: 84863214324     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.04.028     Document Type: Article

References (66)

1. D.F. Williams Titanium and titanium alloys, biocompatibility of clinical implant materials 1982 CRC Press Boca Raton, FL
2. M. Long, and H.J. Rack Titanium alloys in total joint replacement - a materials science perspective Biomaterials 19 1998 1621 1639
3. M. Niinomi Recent research and development in titanium alloys for biomedical applications and healthcare goods Sci Technol Adv Mater 4 2003 445 454
4. H.J. Rack, and J.I. Qazi Titanium alloys for biomedical applications Mater Sci Eng C 26 2006 1269 1277
5. Y.L. Hao, S.J. Li, S.Y. Sun, C.Y. Zheng, and R. Yang Elastic deformation behaviour of Ti-24Nb-4Zr-7.9Sn for biomedical applications Acta Biomater 3 2007 277 286
6. Y.L. Hao, S.J. Li, S.Y. Sun, C.Y. Zheng, Q.M. Hu, and R. Yang Super-elastic titanium alloy with unstable plastic deformation Appl Phys Lett 87 2005 091906-1 091906-3
7. J.D. Currey Bones structure and mechanics 2006 Princeton Uinversity Press Princeton, NJ
8. X.J. Wang, Y.C. Li, P.D. Hodgson, and C.E. Wen Nano- and macro-scale characterisation of the mechanical properties of bovine bone Mater Forum 31 2007 156 159
9. Y. Li, J. Xiong, C.S. Wong, P.D. Hodgson, and C.E. Wen Ti6Ta4Sn alloy and subsequent scaffolding for bone tissue engineering Tissue Eng A 15 2009 3151 3159
10. M. Niinomi, T. Akahori, T. Takeuchi, S. Katsura, H. Fukui, and H. Toda Mechanical properties and cyto-toxicity of new beta type titanium alloy with low melting points for dental applications Mater Sci Eng C 25 2005 417 425
11. D. Eglin, and M. Alini Degradable polymeric materials for osteosynthesis: tutorial Eur Cell Mater 16 2008 80 91
12. O. Laitinen, P. Törmälä, R. Taurio, K. Skutnabb, K. Saarelainen, and T. Iivonen Mechanical properties of biodegradable ligament augmentation device of poly(l-lactide) in vitro and in vivo Biomaterials 13 1992 1012 1016
13. K. Rezwan, Q.Z. Chen, J.J. Blaker, and A.R. Boccaccini Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering Biomaterials 27 2006 3413 3431
14. M.P. Staiger, A.M. Pietak, J. Huadmai, and G. Dias Magnesium and its alloys as orthopedic biomaterials: a review Biomaterials 27 2006 1728 1734
15. F. Witte The history of biodegradable magnesium implants: a review Acta Biomater 6 2010 1680 1692
16. Denkena B, Witte F, Podolsky C, Lucas A. Degradable implants made of magenesium alloys. In: Proceedings of the 5th Euspen International Conference, Montpellier. UK: Euspen; 2005, p. 735-8.
17. A. Hartwig Role of magnesium in genomic stability Mutat Res Fund Mol Med 475 2001 113 121
18. T. Okuma Magnesium and bone strength Nutrition 17 2001 679 680
19. N.-E.L. Saris, E. Mervaala, H. Karppanen, J.A. Khawaja, and A. Lewenstam Magnesium: an update on physiological, clinical and analytical aspects Clin Chim Acta 294 2000 1 26
20. J. Vormann Magnesium: nutrition and metabolism Mol Aspects Med 24 2003 27 37
21. F. Witte, V. Kaese, H. Haferkamp, E. Switzer, A. Meyer-Lindenberg, and C.J. Wirth In vivo corrosion of four magnesium alloys and the associated bone response Biomaterials 26 2005 3557 3563
22. A. Pietak, P. Mahoney, J. Dias George, and P. Staiger Mark Bone-like matrix formation on magnesium and magnesium alloys J Mater Sci Mater Med 19 2008 407 415
23. L.G. Gibson, and M.F. Ashby Cellular solids: structure and properties 1997 Cambridge University Press Cambridge
24. B. Denkena, and A. Lucas Biocompatible magnesium alloys as absorbable implant materials - adjusted surface and subsurface properties by machining processes CIRP Ann Manuf Tech 56 2007 113 116
25. A.C. Hänzi, I. Gerber, M. Schinhammer, J.F. Löffler, and P.J. Uggowitzer On the in vitro and in vivo degradation performance and biological response of new biodegradable Mg-Y-Zn alloys Acta Biomater 6 2010 1824 1833
26. H.Y. López, D.A. Cortés, S. Escobedo, and D. Mantovani In vitro bioactivity assessment of metallic magnesium Key Eng Mater 309-311 2006 453 456
27. M. Alvarez-Lopez, M.D. Pereda, J.A. del Valle, M. Fernandez-Lorenzo, M.C. Garcia-Alonso, and O.A. Ruano Corrosion behaviour of AZ31 magnesium alloy with different grain sizes in simulated biological fluids Acta Biomater 6 2010 1763 1771
28. F. Witte, N. Hort, C. Vogt, S. Cohen, K.U. Kainer, and R. Willumeit Degradable biomaterials based on magnesium corrosion Curr Opin Solid State Mater Sci 12 2008 63 72
29. M.M. Avedesian, and H. Baker Magnesium and Magnesium Alloys 2nd ed. 1999 ASM International Materials Park, OH
30. Kainer KU, von Buch F. The current state of technology and potential for further development of magnesium applications. In: Magnesium - Alloys and Technology, Weinheim: Wiley-VCH Verlag; 2004, p. 1-22.
31. F. Witte, J. Fischer, J. Nellesen, H.-A. Crostack, V. Kaese, and A. Pisch In vitro and in vivo corrosion measurements of magnesium alloys Biomaterials 27 2006 1013 1018
32. F. Witte, J. Fischer, J. Nellesen, C. Vogt, J. Vogt, and T. Donath In vivo corrosion and corrosion protection of magnesium alloy LAE442 Acta Biomater 6 2010 1792 1799
33. Y. Okazaki, S. Rao, S. Asao, T. Tateishi, S. Katsuda, and Y. Furuki Effects of Ti, Al and V concentrations on cell viability Mater Trans JIM 39 1998 1053 1062
34. Y. Okazaki, S. Rao, T. Tateishi, and Y. Ito Cytocompatibility of various metal and development of new titanium alloys for medical implants Mater Sci Eng A 243 1998 250 256
35. Y. Li, P. Hodgson, and C.E. Wen The effects of calcium and yttrium additions on the microstructure, mechanical properties and biocompatibility of biodegradable magnesium alloys J Mater Sci 46 2011 365 371
36. Y. Li, M. Li, W. Hu, P. Hodgson, and C.E. Wen Biodegradable Mg-Ca and Mg-Ca-Y alloys for regenerative medicine Mater Sci Forum 654-656 2010 2192 2195
37. G. Fosmire Zinc toxicity Am J Clin Nutr 51 1990 225 227
38. J.C. Wataha Biocompatibility of dental casting alloys: a review J Prosthet Dent 83 2000 223 234
39. A.-R. Wu, and C.-Q. Xia Study of the microstructure and mechanical properties of Mg-rare earth alloys Mater Design 28 2007 1963 1967
40. J. Gao, S. Wu, L. Qiao, and Y. Wang Corrosion behavior of Mg and Mg-Zn alloy in simulated body fluid Trans Nonferrous Met Soc China 18 2008 588 592
41. K.W. Guo A review of magnesium/magnesium alloys corrosion and its protection Recent Pat Corr Sci 2 2010 13 21
42. A. Yamamoto, R. Honma, and M. Sumita Cytotoxicity evaluation of 43 metal salts using murine fibroblasts and osteoblastic cells J Biomed Mater Res 39 1998 331 340
43. E. Eisenbarth, D. Velten, M. Muller, R. Thull, and J. Breme Biocompatibility of β-stabilizing elements of titanium alloys Biomaterials 25 2004 5705 5713
44. H. Matsuno, A. Yokoyama, F. Watari, M. Uo, and T. Kawasaki Biocompatibility and osteogenesis of refractory metal implants, titanium, hafnium, niobium, tantalum and rhenium Biomaterials 22 2001 1253 1262
45. W. Geurtsen Biocompatibility of dental alloys Crit Rev Oral Biol Med 13 2002 71 78
46. R.-H. Li, F.-S. Pan, B. Jiang, H.-M. Yin, and T.-T. Liu Effects of yttrium and strontium additions on as-cast microstructure of Mg-14Li-1Al alloys Trans Nonferrous Met Soc China 21 2011 778 783
47. M. Yang, F. Pan, R. Cheng, and A. Tang Comparation about efficiency of Al-10Sr and Mg-10Sr master alloys to grain refinement of AZ31 magnesium alloy J Mater Sci 42 2007 10074 10079
48. R.-J. Cheng, F.-S. Pan, M.-B. Yang, and A.-T. Tang Effects of various Mg-Sr master alloys on microstructural refinement of ZK60 magnesium alloy Trans Nonferrous Met Soc China 18 Suppl. 1 2008 s50 s54
49. G. Atkins, K. Welldon, P. Halbout, and D. Findlay Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprotegerin response Osteoporos Int 20 2009 653 664
50. A. Sadeghi, and M. Pekguleryuz Microstructure, mechanical properties and texture evolution of AZ31 alloy containing trace levels of strontium Mater Charact 62 2011 742 750
51. 2 doped [beta]-TCP Bone 48 2011 1282 1290
52. S.S. Banerjee, S. Tarafder, N.M. Davies, A. Bandyopadhyay, and S. Bose Understanding the influence of MgO and SrO binary doping on the mechanical and biological properties of [beta]-TCP ceramics Acta Biomater 6 2010 4167 4174
53. N.N. Aung, and W. Zhou Effect of grain size and twins on corrosion behaviour of AZ31B magnesium alloy Corr Sci 52 2010 589 594
54. S.B. Rodan, Y. Imai, M.A. Thiede, G. Wesolowski, D. Thompson, and Z. Bar-Shavit Characterization of a human osteosarcoma cell line (saos-2) with osteoblastic properties Cancer Res 47 1987 4961 4966
55. X. Gu, Y. Zheng, Y. Cheng, S. Zhong, and T. Xi In vitro corrosion and biocompatibility of binary magnesium alloys Biomaterials 30 2009 484 498
56. Y. Li, C. Wong, J. Xiong, P. Hodgson, and C. Wen Cytotoxicity of titanium and titanium alloying elements J Dent Res 89 2010 493 497
57. R.G. Erben Embedding of bone samples in methylmethacrylate: an improved method suitable for bone histomorphometry, histochemistry, and immunohistochemistry J Histochem Cytochem 45 1997 307 313
58. L.G. Luna Manual of histologic staining methods of the armed forces institute of pathology 3rd ed. 1968 McGraw-Hill New York
59. Nayeb-Hashemi AA, Clark JB, ASM International. Phase diagrams of binary magnesium alloys. Metals Park, OH: ASM, International, 1988.
60. T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Methods 65 1983 55 63
61. D. Song, A. Ma, J. Jiang, P. Lin, D. Yang, and J. Fan Corrosion behavior of equal-channel-angular-pressed pure magnesium in NaCl aqueous solution Corr Sci 52 2010 481 490
62. J. Jiang, A. Ma, N. Saito, Z. Shen, D. Song, and F. Lu Improving corrosion resistance of RE-containing magnesium alloy ZE41A through ECAP J Rare Earths 27 2009 848 852
63. M.-C. Zhao, M. Liu, G.-L. Song, and A. Atrens Influence of pH and chloride ion concentration on the corrosion of Mg alloy ZE41 Corr Sci 50 2008 3168 3178
64. Z. Shi, M. Liu, and A. Atrens Measurement of the corrosion rate of magnesium alloys using Tafel extrapolation Corr Sci 52 2010 579 588
65. J.-W. Park, Y.-J. Kim, and J.-H. Jang Enhanced osteoblast response to hydrophilic strontium and/or phosphate ions-incorporated titanium oxide surfaces Clin Oral Implant Res 21 2010 398 408
66. N. Lakhkar, E.A.A. Neel, V. Salih, and J.C. Knowles Titanium and strontium-doped phosphate glasses as vehicles for strontium ion delivery to cells J Biomater Appl 25 2011 877 893