Titanium and strontium-doped phosphate glasses as vehicles for strontium ion delivery to cells

Journal of Biomaterials Applications

Volumn 25, Issue 8, 2011, Pages 877-893

  Lakhkar, Nilay ^a   Abou Neel, Ensanya A ^a   Salih, Vehid ^a   Knowles, Jonathan Campbell ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

biocompatibility; dental applications.; phosphate glasses; strontium oxide; titanium oxide

Indexed keywords

CELL ATTACHMENTS; DEGRADATION STUDY; DENTAL APPLICATIONS; GLASS COMPOSITIONS; GLASS DEGRADATION; MG63 CELLS; PHOSPHATE GLASS; PHOSPHATE GLASSES; SHORT PERIODS; STRONTIUM ION; STRONTIUM OXIDE; STRUCTURAL CHARACTERIZATION;

BIOCOMPATIBILITY; CALCIUM PHOSPHATE; DEGRADATION; STRONTIUM; TITANIUM; TITANIUM DIOXIDE;

GLASS;

BIOMATERIAL; DRUG CARRIER; DRUG VEHICLE; GLASS; ION; OXIDE; SODIUM OXIDE CALCIUM OXIDE DIPHOSPHORUS PENTOXIDE GLASS; SODIUM OXIDE-CALCIUM OXIDE-DIPHOSPHORUS PENTOXIDE GLASS; STRONTIUM; TITANIUM; TITANIUM DIOXIDE;

ARTICLE; CELL ADHESION; CELL LINE; CELL PROLIFERATION; CHEMISTRY; HUMAN; MATERIALS TESTING; METHODOLOGY; SURFACE PROPERTY; X RAY DIFFRACTION;

BIOCOMPATIBLE MATERIALS; CELL ADHESION; CELL LINE; CELL PROLIFERATION; DRUG CARRIERS; GLASS; HUMANS; IONS; MATERIALS TESTING; OXIDES; PHARMACEUTICAL VEHICLES; STRONTIUM; SURFACE PROPERTIES; TITANIUM; X-RAY DIFFRACTION;

EID: 79957647603     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328210362125     Document Type: Article

References (25)

1. Wren, A., Boyd, D. and Towler, M.R. The Processing, Mechanical Properties and Bioactivity of Strontium Based Glass Polyalkenoate Cements, J. Mater. Sci. Mater. Med., 2008: 19: 1737-1743. (Pubitemid 351388896)
2. Guo, D., Xu, K., Zhao, X. and Han, Y. Development of a Strontium Containing Hydroxyapatite Bone Cement, Biomaterials, 2005: 26: 4073-4083. (Pubitemid 40138654)
3. Wong, C.T., Chen, Q.Z., Lu, W.W., et al. Ultrastructural Study of Mineralization of a Strontium-containing Hydroxyapatite (Sr-HA) Cement In Vivo, J. Biomed. Mater. Res., 2004: 70A: 428-435.
4. Marie, P.J., Ammann, P., Boivin, G. and Rey, C. Mechanisms of Action and Therapeutic Potential of Strontium in Bone, Calcif. Tissue Int., 2001: 69: 121-129. (Pubitemid 32912229)
5. Verberckmoes, S.C., De Broe, M.E. and D'Haese, P.C. Dose-Dependent Effects of Strontium on Osteoblast Function and Mineralization, Kidney Int., 2003: 64: 534-543. (Pubitemid 36871924)
6. Kraeber-Bodéré, F., Campion, L., Rousseau, C., Bourdin, S., Chatal, J.-F. and Resche, I. Treatment of Bone Metastases of Prostate Cancer with Strontium-89 Chloride: Efficacy in Relation to the Degree of Bone Involvement, Eur. J. Nucl. Med., 2000: 27: 1487-1493.
7. Guida, A., Towler, M.R., Wall, J.G., Hill, R.G. and Eramo, S. Preliminary Work on the Antibacterial Effect of Strontium in Glass Ionomer Cements, J. Mater. Sci. Lett., 2003: 22: 1401-1403.
8. Pina, S., Torres, P.M., Goetz-Neunhoeffer, F., Neubauer, J. and Ferreira, J.M.F. Newly Developed Sr-substituted I-TCP Bone Cements, Acta Biomater., 2009: 6: 928-935.
9. Wu, C., Ramaswamy, Y., Kwik, D. and Zreiqat, H. The Effect of Strontium Incorporation Into CaSiO3 Ceramics on their Physical and Biological Properties, Biomaterials, 2007: 28: 3171-3181. (Pubitemid 46661856)
10. Lao, J., Jallot, E. and Nedelec, J.M. Strontium-Delivering Glasses With Enhanced Bioactivity: A New Biomaterial for Antiosteoporotic Applications? Chem. Mater., 2008: 20: 4969-4973.
11. Towler, M., Boyd, D., Freeman, C., Brook, I.M. and Farthing, P. Comparison of In Vitro and In Vivo Bioactivity of SrO-CaO-ZnO-SiO2 Glass Grafts, J. Biomater. Appl., 2009: 23: 561-572.
12. Franks, K., Abrahams, I. and Knowles, J.C. Development of Soluble Glasses for Biomedical Use Part I: In Vitro Solubility Measurement, J. Mater. Sci. Mater. Med., 2000: 11: 609-614.
13. Salih, V., Franks, K., James, M., Hastings, G.W., Knowles, J.C. and Olsen, I. Development of Soluble Glasses for Biomedical Use Part II: The Biological Response of Human Osteoblast Cell Lines to Phosphate-based Soluble Glasses, J. Mater. Sci. Mater. Med., 2000: 11: 615-620.
14. Knowles, J.C. Phosphate Based Glasses for Biomedical Applications, J. Mater. Chem., 2003: 13: 2395-2401.
15. Yu, X.Y., Day, D.E., Long, G.J. and Brow, R.K. Properties and Structure of Sodium-Iron Phosphate Glasses, J. Non-Cryst. Solids, 1997: 215: 21-31.
16. Ray, C.S., Fang, X., Karabulut, M., Marasinghe, G.K. and Day, D.E. Effect of Melting Temperature and Time on Iron Valence and Crystallization of Iron Phosphate Glasses, J. Non-Cryst. Solids, 1999: 249: 1-16.
17. Abou Neel, E.A., O'Dell, L.A., Smith, M.E. and Knowles, J.C. Processing, Characterisation, and Biocompatibility of Zinc Modified Metaphosphate Based Glasses for Biomedical Applications, J. Mater. Sci. Mater. Med., 2008: 19: 1669-1679.
18. Valappil, S.P., Knowles, J.C. and Wilson, M. Effect of Silver-doped Phosphate-based Glasses on Bacterial Biofilm Growth, Appl. Environ. Microbiol., 2008: 74: 5228-5230.
19. Navarro, M., Ginebra, M.-P. and Planell, J.A. Cellular Response to Calcium Phosphate Glasses with Controlled Solubility, J. Biomed. Mater. Res. A, 2003: 67A: 1009-1015. (Pubitemid 37521577)
20. Rajendran, V., Gayathri Devi, A.V., Azooz, M. and El-Batal, F.H. Physicochemical Studies of Phosphate Based P2O5-Na2O-CaO- TiO2 Glasses for Biomedical Applications, J. Non-Cryst. Solids, 2006: 353: 77-84. (Pubitemid 44853960)
21. Abou Neel, E.A. and Knowles, J.C. Physical and Biocompatibility Studies of Novel Titanium Dioxide Doped Phosphate-based Glasses for Bone Tissue Engineering Applications, J. Mater. Sci. Mater. Med., 2008: 19: 377-386.
22. Abou Neel, E.A., Chrzanowski, W., Pickup, D.M., et al. Structure and Properties of Strontium-Doped Phosphate-Based Glasses, J. R. Soc. Interface, 2008: 6: 435-446.
23. Lakhkar, N.J., Abou Neel, E.A., Salih, V. and Knowles, J.C. Strontium Oxide Doped Quaternary Glasses: Effect on Structure, Degradation and Cytocompatibility, J. Mater. Sci. Mater. Med., 2009: 20: 1339-1246.
24. Pickup, D.M., Guerry, P., Moss, R.M., Knowles, J.C., Smith, M.E. and Newport, R.J. New Sol-Gel Synthesis of a (CaO)0.3(Na2O)0.2(P2O5)0.5 Bioresorbable Glass and Its Structural Characterisation, J. Mater. Chem., 2007: 17: 4777-4784.
25. Chen, Q.Z., Efthymiou, A., Salih, V. and Boccaccini, A.R. Bioglass®Derived Glass-Ceramic Scaffolds: Study of Cell Proliferation and Scaffold Degradation In Vitro, J. Biomed. Mater. Res. A, 2008: 84A: 1049-1060. (Pubitemid 351295015)