메뉴 건너뛰기




Volumn 22, Issue 8, 2012, Pages 1128-1139

Detailed O-glycomics of the Muc2 mucin from colon of wild-type, core 1- and core 3-transferase-deficient mice highlights differences compared with human MUC2

Author keywords

LC; Mass spectrometry; Mucin; Murine; O glycosylation

Indexed keywords

GLYCAN DERIVATIVE; MUCIN 2; N ACETYLGLUCOSAMINE;

EID: 84863197183     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cws083     Document Type: Article
Times cited : (74)

References (40)
  • 1
    • 34250378697 scopus 로고    scopus 로고
    • Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans
    • DOI 10.1084/jem.20061929
    • An G, Wei B, Xia B, McDaniel JM, Ju T, Cummings RD, Braun J, Xia L. 2007. Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. J Exp Med. 204:1417-1429. (Pubitemid 46919879)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.6 , pp. 1417-1429
    • An, G.1    Wei, B.2    Xia, B.3    McDaniel, J.M.4    Ju, T.5    Cummings, R.D.6    Braun, J.7    Xia, L.8
  • 2
    • 34247371926 scopus 로고    scopus 로고
    • Large scale identification of proteins, mucins and their O-glycosylation in the endocervical mucus during the menstrual cycle
    • DOI 10.1074/mcp.M600439-MCP200
    • Andersch-Bjorkman Y, Thomsson KA, Holmen Larsson JM, Ekerhovd E, Hansson GC. 2007. Large scale identification of proteins, mucins, and their O-glycosylation in the endocervical mucus during the menstrual cycle. Mol Cell Proteomics. 6:708-716. (Pubitemid 46630103)
    • (2007) Molecular and Cellular Proteomics , vol.6 , Issue.4 , pp. 708-716
    • Andersch-Bjorkman, Y.1    Thomsson, K.A.2    Holmen, L.J.M.3    Ekerhovd, E.4    Hansson, G.C.5
  • 3
    • 0032563105 scopus 로고    scopus 로고
    • O-glycosylated MUC2 monomer and dimer from LS 174T cells are water- soluble, whereas larger MUC2 species formed early during biosynthesis are insoluble and contain nonreducible intermolecular bonds
    • DOI 10.1074/jbc.273.30.18864
    • Axelsson MA, Asker N, Hansson GC. 1998. O-glycosylated MUC2 monomer and dimer from LS 174T cells are water-soluble, whereas larger MUC2 species formed early during biosynthesis are insoluble and contain nonreducible intermolecular bonds. J Biol Chem. 273:18864-18870. (Pubitemid 28366273)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.30 , pp. 18864-18870
    • Axelsson, M.A.B.1    Asker, N.2    Hansson, G.C.3
  • 4
    • 15544369658 scopus 로고    scopus 로고
    • Host-bacterial mutualism in the human intestine
    • DOI 10.1126/science.1104816
    • Backhed F, Ley RE, Sonnenburg JL, Peterson DA, Gordon JI. 2005. Host-bacterial mutualism in the human intestine. Science. 307:1915-1920. (Pubitemid 40404694)
    • (2005) Science , vol.307 , Issue.5717 , pp. 1915-1920
    • Backhed, F.1    Ley, R.E.2    Sonnenburg, J.L.3    Peterson, D.A.4    Gordon, J.I.5
  • 5
    • 0035884645 scopus 로고    scopus 로고
    • a-antigen-like structures carried on core 3 are prominent features of glycans from the mucin of normal human descending colon
    • Capon C, Maes E, Michalski JC, Leffler H, Kim YS. 2001. Sd(a)-antigen-like structures carried on core 3 are prominent features of glycans from the mucin of normal human descending colon. Biochem J. 358:657-664. (Pubitemid 32896953)
    • (2001) Biochemical Journal , vol.358 , Issue.3 , pp. 657-664
    • Capon, C.1    Maes, E.2    Michalski, J.-C.3    Leffler, H.4    Kim, Y.S.5
  • 6
    • 45549094069 scopus 로고    scopus 로고
    • GlycoWorkbench: A tool for the computer-assisted annotation of mass spectra of glycans
    • Ceroni A, Maass K, Geyer H, Geyer R, Dell A, Haslam SM. 2008. GlycoWorkbench: A tool for the computer-assisted annotation of mass spectra of glycans. J Proteome Res. 7:1650-1659.
    • (2008) J Proteome Res , vol.7 , pp. 1650-1659
    • Ceroni, A.1    Maass, K.2    Geyer, H.3    Geyer, R.4    Dell, A.5    Haslam, S.M.6
  • 8
    • 0037252356 scopus 로고    scopus 로고
    • Two glycosylation alterations of mouse intestinal mucins due to infection caused by the parasite Nippostrongylus brasiliensis
    • DOI 10.1023/A:1022589015687
    • Holmen JM, Olson FJ, Karlsson H, Hansson GC. 2002. Two glycosylation alterations of mouse intestinal mucins due to infection caused by the parasite Nippostrongylus brasiliensis. Glycoconj J. 19:67-75. (Pubitemid 36408002)
    • (2002) Glycoconjugate Journal , vol.19 , Issue.1 , pp. 67-75
    • Holmen, J.M.1    Olson, F.J.2    Karlsson, H.3    Hansson, G.C.4
  • 9
    • 27244460624 scopus 로고    scopus 로고
    • Gastrointestinal mucins of Fut2-null mice lack terminal fucosylation without affecting colonization by Candida albicans
    • DOI 10.1093/glycob/cwi089
    • Hurd EA, Holmen JM, Hansson GC, Domino SE. 2005. Gastrointestinal mucins of Fut2-null mice lack terminal fucosylation without affecting colonization by Candida albicans. Glycobiology. 15:1002-1007. (Pubitemid 41511494)
    • (2005) Glycobiology , vol.15 , Issue.10 , pp. 1002-1007
    • Hurd, E.A.1    Holmen, J.M.2    Hansson, G.C.3    Domino, S.E.4
  • 11
    • 0037066753 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel UDP-GlcNAc: GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans
    • DOI 10.1074/jbc.M112457200
    • Iwai T, Inaba N, Naundorf A, Zhang Y, Gotoh M, Iwasaki H, Kudo T, Togayachi A, Ishizuka Y, Nakanishi H, et al. 2002. Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N- acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans. J Biol Chem. 277:12802-12809. (Pubitemid 34952643)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.15 , pp. 12802-12809
    • Iwai, T.1    Inaba, N.2    Naundorf, A.3    Zhang, Y.4    Gotoh, M.5    Iwasaki, H.6    Kudo, T.7    Togayachi, A.8    Ishizuka, Y.9    Nakanishi, H.10    Narimatsu, H.11
  • 15
    • 67650394385 scopus 로고    scopus 로고
    • Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein
    • Johansson ME, Thomsson KA, Hansson GC. 2009. Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein. J Proteome Res. 8:3549-3557.
    • (2009) J Proteome Res , vol.8 , pp. 3549-3557
    • Johansson, M.E.1    Thomsson, K.A.2    Hansson, G.C.3
  • 16
    • 84855500089 scopus 로고    scopus 로고
    • Microbial adhesins to gastrointestinal mucus
    • Juge N. 2012. Microbial adhesins to gastrointestinal mucus. Trends Microbiol. 20:30-39.
    • (2012) Trends Microbiol , vol.20 , pp. 30-39
    • Juge, N.1
  • 18
    • 0024339704 scopus 로고
    • Animal glycosphingolipids as membrane attachment sites for bacteria
    • Karlsson KA. 1989. Animal glycosphingolipids as membrane attachment sites for bacteria. Annu Rev Biochem. 58:309-350.
    • (1989) Annu Rev Biochem , vol.58 , pp. 309-350
    • Karlsson, K.A.1
  • 20
    • 80054767981 scopus 로고    scopus 로고
    • Altered O-glycosylation profile of MUC2 mucin occurs in active ulcerative colitis and is associated with increased inflammation
    • Larsson JM, Karlsson H, Crespo JG, Johansson ME, Eklund L, Sjovall H, Hansson GC. 2011. Altered O-glycosylation profile of MUC2 mucin occurs in active ulcerative colitis and is associated with increased inflammation. Inflamm Bowel Dis. 17:2299-2307.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 2299-2307
    • Larsson, J.M.1    Karlsson, H.2    Crespo, J.G.3    Johansson, M.E.4    Eklund, L.5    Sjovall, H.6    Hansson, G.C.7
  • 21
    • 66249136714 scopus 로고    scopus 로고
    • A complex, but uniform O-glycosylation of the human MUC2 mucin from colonic biopsies analyzed by nanoLC/MSn
    • Larsson JM, Karlsson H, Sjovall H, Hansson GC. 2009. A complex, but uniform O-glycosylation of the human MUC2 mucin from colonic biopsies analyzed by nanoLC/MSn. Glycobiology. 19:756-766.
    • (2009) Glycobiology , vol.19 , pp. 756-766
    • Larsson, J.M.1    Karlsson, H.2    Sjovall, H.3    Hansson, G.C.4
  • 23
    • 71049182586 scopus 로고    scopus 로고
    • Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa
    • Magalhaes A, Gomes J, Ismail MN, Haslam SM, Mendes N, Osorio H, David L, Le PJ, Haas R, Dell A, et al. 2009. Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa. Glycobiology. 19:1525-1536.
    • (2009) Glycobiology , vol.19 , pp. 1525-1536
    • Magalhaes, A.1    Gomes, J.2    Ismail, M.N.3    Haslam, S.M.4    Mendes, N.5    Osorio, H.6    David, L.7    Le, P.J.8    Haas, R.9    Dell, A.10
  • 25
    • 13644270922 scopus 로고    scopus 로고
    • A MUC1 tandem repeat reporter protein produced in CHO-K1 cells has sialylated core 1 O-glycans and becomes more densely glycosylated if coexpressed with polypeptide-GalNAc-T4 transferase
    • Olson FJ, Backstrom M, Karlsson H, Burchell J, Hansson GC. 2005. A MUC1 tandem repeat reporter protein produced in CHO-K1 cells has sialylated core 1 O-glycans and becomes more densely glycosylated if coexpressed with polypeptide-GalNAc-T4 transferase. Glycobiology. 15:177-191.
    • (2005) Glycobiology , vol.15 , pp. 177-191
    • Olson, F.J.1    Backstrom, M.2    Karlsson, H.3    Burchell, J.4    Hansson, G.C.5
  • 26
    • 0037177858 scopus 로고    scopus 로고
    • Blood group A glycosyltransferase occurring as alleles with high sequence difference is transiently induced during a Nippostrongylus brasiliensis parasite infection
    • DOI 10.1074/jbc.M112287200
    • Olson FJ, Johansson ME, Klinga-Levan K, Bouhours D, Enerback L, Hansson GC, Karlsson NG. 2002. Blood group A glycosyltransferase occurring as alleles with high sequence difference is transiently induced during a Nippostrongylus brasiliensis parasite infection. J Biol Chem. 277:15044-15052. (Pubitemid 34952581)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.17 , pp. 15044-15052
    • Olson, F.J.1    Johansson, M.E.V.2    Klinga-Levan, K.3    Bouhours, D.4    Enerback, L.5    Hansson, G.C.6    Karlsson, N.G.7
  • 27
    • 33749997498 scopus 로고    scopus 로고
    • Reciprocal Gut Microbiota Transplants from Zebrafish and Mice to Germ-free Recipients Reveal Host Habitat Selection
    • DOI 10.1016/j.cell.2006.08.043, PII S0092867406012268
    • Rawls JF, Mahowald MA, Ley RE, Gordon JI. 2006. Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection. Cell. 127:423-433. (Pubitemid 44572375)
    • (2006) Cell , vol.127 , Issue.2 , pp. 423-433
    • Rawls, J.F.1    Mahowald, M.A.2    Ley, R.E.3    Gordon, J.I.4
  • 28
    • 1242339631 scopus 로고    scopus 로고
    • Diagnostic ions for the rapid analysis by nano-electrospray ionization quadrupole time-of-flight mass spectrometry of O-glycans from human mucins
    • Robbe C, Capon C, Coddeville B, Michalski JC. 2004a. Diagnostic ions for the rapid analysis by nano-electrospray ionization quadrupole time-of-flight mass spectrometry of O-glycans from human mucins. Rapid Commun Mass Spectrom. 18:412-420. (Pubitemid 38235175)
    • (2004) Rapid Communications in Mass Spectrometry , vol.18 , Issue.4 , pp. 412-420
    • Robbe, C.1    Capon, C.2    Coddeville, B.3    Michalski, J.-C.4
  • 29
    • 10644254423 scopus 로고    scopus 로고
    • Structural diversity and specific distribution of O-glycans in normal human mucins along the intestinal tract
    • DOI 10.1042/BJ20040605
    • Robbe C, Capon C, Coddeville B, Michalski JC. 2004b. Structural diversity and specific distribution of O-glycans in normal human mucins along the intestinal tract. Biochem J. 384:307-316. (Pubitemid 39656243)
    • (2004) Biochemical Journal , vol.384 , Issue.2 , pp. 307-316
    • Robbe, C.1    Capon, C.2    Coddeville, B.3    Michalski, J.-C.4
  • 30
    • 0344875610 scopus 로고    scopus 로고
    • Evidence of regio-specific glycosylation in human intestinal mucins: Presence of an acidic gradient along the intestinal tract
    • DOI 10.1074/jbc.M302529200
    • Robbe C, Capon C, Maes E, Rousset M, Zweibaum A, Zanetta JP, Michalski JC. 2003. Evidence of regio-specific glycosylation in human intestinal mucins: Presence of an acidic gradient along the intestinal tract. J Biol Chem. 278:46337-46348. (Pubitemid 37452204)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.47 , pp. 46337-46348
    • Robbe, C.1    Capon, C.2    Maes, E.3    Rousset, M.4    Zweibaum, A.5    Zanetta, J.-P.6    Michalski, J.-C.7
  • 32
    • 0036894272 scopus 로고    scopus 로고
    • Small-scale analysis of O-linked oligosaccharides from glycoproteins and mucins separated by gel electrophoresis
    • DOI 10.1021/ac025890a
    • Schulz BL, Packer NH, Karlsson NG. 2002. Small-scale analysis of O-linked oligosaccharides from glycoproteins and mucins separated by gel electrophoresis. Anal Chem. 74:6088-6097. (Pubitemid 35428807)
    • (2002) Analytical Chemistry , vol.74 , Issue.23 , pp. 6088-6097
    • Schulz, B.L.1    Packer, N.H.2    Karlsson, N.G.3
  • 34
    • 45749155148 scopus 로고    scopus 로고
    • Characterization of mouse sialyltransferase genes: Their evolution and diversity
    • DOI 10.1271/bbb.80025
    • Takashima S. 2008. Characterization of mouse sialyltransferase genes: Their evolution and diversity. Biosci Biotechnol Biochem. 72:1155-1167. (Pubitemid 351872478)
    • (2008) Bioscience, Biotechnology and Biochemistry , vol.72 , Issue.5 , pp. 1155-1167
    • Takashima, S.1
  • 35
    • 76849083068 scopus 로고    scopus 로고
    • Enhanced detection of sialylated and sulfated glycans with negative ion mode nanoliquid chromatography/mass spectrometry at high pH
    • Thomsson KA, Backstrom M, Holmen Larsson JM, Hansson GC, Karlsson H. 2010. Enhanced detection of sialylated and sulfated glycans with negative ion mode nanoliquid chromatography/mass spectrometry at high pH. Anal Chem. 82:1470-1477.
    • (2010) Anal Chem , vol.82 , pp. 1470-1477
    • Thomsson, K.A.1    Backstrom, M.2    Holmen Larsson, J.M.3    Hansson, G.C.4    Karlsson, H.5
  • 37
    • 0034307401 scopus 로고    scopus 로고
    • Sequencing of sulfated oligosaccharides from mucins by liquid chromatography and electrospray ionization tandem mass spectrometry
    • Thomsson KA, Karlsson H, Hansson GC. 2000. Sequencing of sulfated oligosaccharides from mucins by liquid chromatography and electrospray ionization tandem mass spectrometry. Anal Chem. 72:4543-4549.
    • (2000) Anal Chem , vol.72 , pp. 4543-4549
    • Thomsson, K.A.1    Karlsson, H.2    Hansson, G.C.3
  • 38
    • 25144448202 scopus 로고    scopus 로고
    • MUC5B glycosylation in human saliva reflects blood group and secretor status
    • DOI 10.1093/glycob/cwi059
    • Thomsson KA, Schulz BL, Packer NH, Karlsson NG. 2005. MUC5B glycosylation in human saliva reflects blood group and secretor status. Glycobiology. 15:791-804. (Pubitemid 41417982)
    • (2005) Glycobiology , vol.15 , Issue.8 , pp. 791-804
    • Thomsson, K.A.1    Schulz, B.L.2    Packer, N.H.3    Karlsson, N.G.4
  • 39
    • 77949887188 scopus 로고    scopus 로고
    • Sulfation of colonic mucins by N-acetylglucosamine 6-O-sulfotransferase-2 and its protective function in experimental colitis in mice
    • Tobisawa Y, Imai Y, Fukuda M, Kawashima H. 2010. Sulfation of colonic mucins by N-acetylglucosamine 6-O-sulfotransferase-2 and its protective function in experimental colitis in mice. J Biol Chem. 285:6750-6760.
    • (2010) J Biol Chem , vol.285 , pp. 6750-6760
    • Tobisawa, Y.1    Imai, Y.2    Fukuda, M.3    Kawashima, H.4
  • 40
    • 0028329138 scopus 로고
    • a+b-) patient suffering from chronic bronchitis. Characterization of a novel type of mucin carbohydrate core structure
    • van Halbeek H, Strang AM, Lhermitte M, Rahmoune H, Lamblin G, Roussel P. 1994. Structures of monosialyl oligosaccharides isolated from the respiratory mucins of a non-secretor (O, Lea+b-) patient suffering from chronic bronchitis. Characterization of a novel type of mucin carbohydrate core structure. Glycobiology. 4:203-219. (Pubitemid 24147896)
    • (1994) Glycobiology , vol.4 , Issue.2 , pp. 203-219
    • Van Halbeek, H.1    Strang, A.-M.2    Lhermitte, M.3    Rahmoune, H.4    Lamblin, G.5    Roussel, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.