In vitro and in vivo characterization of silk fibroin/gelatin composite scaffolds for liver tissue engineering

Journal of Digestive Diseases

Volumn 13, Issue 3, 2012, Pages 168-178

  Yang, Zhao ^a   Xu, Li Sha ^a   Yin, Fang ^a   Shi, Yong Quan ^a   Han, Ying ^a   Zhang, Lin ^a   Jin, Hai Feng ^a   Nie, Yong Zhan ^a   Wang, Jing Bo ^a   Hao, Xing ^b   Fan, Dai Ming ^a   Zhou, Xin Min ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Biocompatibility; Cytotoxicity; Gelatin; Liver tissue engineering; Silk fibroin

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; EOSIN; GELATIN; HEMATOXYLIN; SILK FIBROIN; TISSUE SCAFFOLD;

APOPTOSIS; ARTICLE; BIOARTIFICIAL LIVER; BIOCOMPATIBILITY; CELL ADHESION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; FIBROBLAST; FLOW CYTOMETRY; GROWTH RATE; HUMAN; HUMAN CELL; IMMUNOLOGICAL PROCEDURES; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LIVER CELL; LIVER GRAFT REJECTION; MICROSCOPY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SPRAGUE DAWLEY RAT; STAINING; TISSUE ENGINEERING;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BIOCOMPATIBLE MATERIALS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; FIBROINS; GELATIN; HEPATOCYTES; HUMANS; MALE; PROSTHESES AND IMPLANTS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84863182014     PISSN: 17512972     EISSN: 17512980     Source Type: Journal    
DOI: 10.1111/j.1751-2980.2011.00566.x     Document Type: Article

References (22)

1. Lee WM, Squires RH Jr, Nyberg SL, Doo E, Hoofnagle JH. Acute liver failure: summary of a workshop. Hepatology 2008; 47: 1401-15.
2. Kjaergard LL, Liu J, Als-Nielsen B, Gluud C. Artificial and bioartificial support systems for acute and acute-on-chronic liver failure: a systematic review. JAMA 2003; 289: 217-22.
3. Kobayashi N. Life support of artificial liver: development of a bioartificial liver to treat liver failure. J Hepatobiliary Pancreat Surg 2009; 16: 113-7.
4. Larouche D, Lavoie A, Proulx S etal. Regenerative medicine: stem cells, cellular and matricial interactions in the reconstruction of skin and cornea by tissue engineering. Pathol Biol (Paris) 2009; 57: 299-308.
5. Sharma B, Elisseeff JH. Engineering structurally organized cartilage and bone tissues. Ann Biomed Eng 2004; 32: 148-59.
6. Hutmacher DW. Scaffolds in tissue engineering bone and cartilage. Biomaterials 2000; 21: 2529-43.
7. Rosso F, Marino G, Giordano A, Barbarisi M, Parmeggiani D, Barbarisi A. Smart materials as scaffolds for tissue engineering. J Cell Physiol 2005; 203: 465-70.
8. Altman GH, Diaz F, Jakuba C etal. Silk-based biomaterials. Biomaterials 2003; 24: 401-16.
9. Kaplan DL, Adams WW, Farmer B, Viney C. Silk: biology, structure, properties and genetics. In: Kaplan DL, Adams WW, Farmer B, Viney C, eds. Silk Polymers: Materials Science and Biotechnology. ACS Symp Ser 1994; 544: 2-16.
10. Guidoin R, Marceau D, Rao TJ etal. In vitro and in vivo characterization of an impervious polyester arterial prosthesis: the Gelseal Triaxial graft. Biomaterials 1987; 8: 433-41.
11. Tabata Y, Hijikata S, Ikada Y. Enhanced vascularization and tissue granulation by basic fibroblast growth factor impregnated in gelatin hydrogels. J Control Release 1994; 31: 189-99.
12. Choi YS, Hong SR, Lee YM, Song KW, Park MH, Nam YS. Study on gelatin-containing artificial skin: I. Preparation and characteristics of novel gelatin-alginate sponge. Biomaterials 1999; 20: 409-17.
13. Lee J, Tae G, Kim YH, Park IS, Kim SH. The effect of gelatin incorporation into electrospun poly(L-lactide-co-epsilon-caprolactone) fibers on mechanical properties and cytocompatibility. Biomaterials 2008; 29: 1872-9.
14. Kang HW, Tabata Y, Ikada Y. Fabrication of porous gelatin scaffolds for tissue engineering. Biomaterials 1999; 20: 1339-44.
15. Hori K, Sotozono C, Hamuro J etal. Controlled-release of epidermal growth factor from cationized gelatin hydrogel enhances corneal epithelial wound healing. J Control Release 2007; 118: 169-76.
16. Chen YW, Chiou SH, Wong TT etal. Using gelatin scaffold with coated basic fibroblast growth factor as a transfer system for transplantation of human neural stem cells. Transplant Proc 2006; 38: 1616-7.
17. Yan L, Han Y, Wang J, Liu J, Hong L, Fan D. Peripheral blood monocytes from patients with HBV related decompensated liver cirrhosis can differentiate into functional hepatocytes. Am J Hematol 2007; 82: 949-54.
18. Li J, Pan J, Zhang L, Guo X, Yu Y. Culture of primary rat hepatocytes within porous chitosan scaffolds. J Biomed Mater Res A 2003; 67: 938-43.
19. Glicklis R, Shapiro L, Agbaria R, Merchuk JC, Cohen S. Hepatocyte behavior within three-dimensional porous alginate scaffolds. Biotechnol Bioeng 2000; 67: 344-53.
20. Yang J, Chung TW, Nagaoka M, Goto M, Cho CS, Akaike T. Hepatocyte-specific porous polymer-scaffolds of alginate/galactosylated chitosan sponge for liver-tissue engineering. Biotechnol Lett 2001; 23: 1385-9.
21. Chen JP, Lin TC. High-density culture of hepatocytes in a packed-bed bioreactor using a fibrous scaffold from plant. Biochem Eng J 2006; 30: 192-8.
22. Chung TW, Yang J, Akaike T etal. Preparation of alginate/galactosylated chitosan scaffold for hepatocyte attachment. Biomaterials 2002; 23: 2827-34.