MicroRNA 335 is required for differentiation of malignant glioma cells induced by activation of cAMP/protein kinase A pathway

Molecular Pharmacology

Volumn 81, Issue 3, 2012, Pages 292-298

  Shu, Minfeng ^a   Zhou, Yuehan ^a   Zhu, Wenbo ^a   Zhang, Haipeng ^a   Wu, Sihan ^a   Chen, Jingkao ^a   Yan, Guangmei ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGOMIR 335; BUCLADESINE; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; GLIAL FIBRILLARY ACIDIC PROTEIN; KT 5720; MICRORNA; MICRORNA 335; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; GLIOMA CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION;

ANIMALS; BASE SEQUENCE; BRAIN NEOPLASMS; CELL DIFFERENTIATION; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA PRIMERS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GLIOMA; HUMANS; MICRORNAS; RATS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84863179521     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.111.076166     Document Type: Article

References (27)

1. Akagi T, Murata K, Shishido T, and Hanafusa H (2002) v-Crk activates the phosphoinositide 3-kinase/AKT pathway by utilizing focal adhesion kinase and H-Ras. Mol Cell Biol 22:7015-7023.
2. Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, and Rich JN (2006) Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444:756-760. (Pubitemid 44949604)
3. Chen L, Yan HX, Yang W, Hu L, Yu LX, Liu Q, Li L, Huang DD, Ding J, Shen F, et al. (2009) The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma. J Hepatol 50:358-369.
4. Curran WJ Jr, Scott CB, Horton J, Nelson JS, Weinstein AS, Fischbach AJ, Chang CH, Rotman M, Asbell SO, and Krisch RE (1993) Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials. J Nat Cancer Inst 85:704-710. (Pubitemid 23133591)
5. DeAngelis LM (2001) Brain tumors. N Engl J Med 344:114-123.
6. Esquela-Kerscher A and Slack FJ (2006) Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 6:259-269.
7. 1 in hepatocellular carcinoma. Mol Biol Rep 38:3029-3035.
8. Gao X, Gulari E, and Zhou X (2004) In situ synthesis of oligonucleotide microarrays. Biopolymers 73:579-596. (Pubitemid 38480705)
9. Guerrant RL, Fang GD, Thielman NM, and Fonteles MC (1994) Role of platelet activating factor in the intestinal epithelial secretory and Chinese hamster ovary cell cytoskeletal responses to cholera toxin. Proc Natl Acad Sci USA 91:9655-9658. (Pubitemid 24297974)
10. He S, Zhu W, Zhou Y, Huang Y, Ou Y, Li Y, and Yan G (2011) Transcriptional and post-transcriptional down-regulation of cyclin D1 contributes to C6 glioma cell differentiation induced by forskolin. J Cell Biochem 112:2241-2249.
11. Huang ME, Ye YC, Chen SR, Chai JR, Lu JX, Zhoa L, Gu LJ, and Wang ZY (1988) Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 72:567-572.
12. Kim YK, Yu J, Han TS, Park SY, Namkoong B, Kim DH, Hur K, Yoo MW, Lee HJ, Yang HK, et al. (2009) Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer. Nucleic Acids Res 37:1672-1681.
13. Li Y, Yin W, Wang X, Zhu W, Huang Y, and Yan G (2007) Cholera toxin induces malignant glioma cell differentiation via the PKA/CREB pathway. Proc Natl Acad Sci USA 104:13438-13443. (Pubitemid 47293963)
14. Lu H, Li Y, Shu M, Tang J, Huang Y, Zhou Y, Liang Y, and Yan G (2009) Hypoxia-inducible factor-1alpha blocks differentiation of malignant gliomas. FEBS J 276: 7291-7304.
15. McKeown-Longo PJ, Hanning R, and Mosher DF (1984) Binding and degradation of platelet thrombospondin by cultured fibroblasts. J Cell Biol 98:22-28. (Pubitemid 14220463)
16. Moss J and Vaughan M (1979) Activation of adenylate cyclase by choleragen. Annu Rev Biochem 48:581-600. (Pubitemid 10191097)
17. Park JK, Lee EJ, Esau C, and Schmittgen TD (2009) Antisense inhibition of microRNA-21 or -221 arrests cell cycle, induces apoptosis, and sensitizes the effects of gemcitabine in pancreatic adenocarcinoma. Pancreas 38:e190-199.
18. Png KJ, Yoshida M, Zhang XH, Shu W, Lee H, Rimner A, Chan TA, Comen E, Andrade VP, Kim SW, et al. (2011) MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer. Genes Dev 25:226-231.
19. Ronchetti D, Lionetti M, Mosca L, Agnelli L, Andronache A, Fabris S, Deliliers GL, and Neri A (2008) An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma. BMC Med Genomics 1:37.
20. Scarola M, Schoeftner S, Schneider C, and Benetti R (2010) miR-335 directly targets Rb1 (pRb/p105) in a proximal connection to p53-dependent stress response. Cancer Res 70:6925-6933.
21. Shu M, Zheng X, Wu S, Lu H, Leng T, Zhu W, Zhou Y, Ou Y, Lin X, Lin Y, et al. (2011a) Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells. Mol Cancer 10:59.
22. Shu M, Zhou Y, Zhu W, Wu S, Zheng X, and Yan G (2011b) Activation of a pro-survival pathway IL-6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin-induced differentiation of C6 malignant glioma cells. Mol Oncol 5:265-272.
23. Takanaga H, Yoshitake T, Hara S, Yamasaki C, and Kunimoto M (2004) cAMP-induced astrocytic differentiation of C6 glioma cells is mediated by autocrine interleukin-6. J Biol Chem 279:15441-15447. (Pubitemid 38618944)
24. Tavazoie SF, Alarcón C, Oskarsson T, Padua D, Wang Q, Bos PD, Gerald WL, and Massagué J (2008) Endogenous human microRNAs that suppress breast cancer metastasis. Nature 451:147-152.
25. Tomé M, López-Romero P, Albo C, Sepúlveda JC, Fernández-Gutiérrez B, Dopazo A, Bernad A, and González MA (2011) miR-335 orchestrates cell proliferation, migration and differentiation in human mesenchymal stem cells. Cell Death Differ 18:985-995.
26. Trog D, Fountoulakis M, Friedlein A, and Golubnitschaja O (2006) Is current therapy of malignant gliomas beneficial for patients? Proteomics evidence of shifts in glioma cells expression patterns under clinically relevant treatment conditions. Proteomics 6:2924-2930.
27. Van Kolen K and Slegers H (2004) P2Y12 receptor stimulation inhibits beta-adrenergic receptor-induced differentiation by reversing the cyclic AMP-dependent inhibition of protein kinase B. J Neurochem 89:442-445.