Inhibitory effect of vitamin U (S-methylmethionine sulfonium chloride) on differentiation in 3T3-L1 pre-adipocyte cell lines

Annals of Dermatology

Volumn 24, Issue 1, 2012, Pages 39-44

  Lee, Na Young ^a   Park, Kui Young ^a   Min, Hye Jung ^b   Song, Kye Yong ^b   Lim, Yun Young ^a   Park, Juhee ^a   Kim, Beom Joon ^a   Kim, Myeung Nam ^a  

^a Chung Ang University   (South Korea)

^b Chung Ang University College of Medicine   (South Korea)

Author keywords

Adipocyte differentiation; S methylmethionine sulfonium chloride; Vitamin U

Indexed keywords

EID: 84863170195     PISSN: 10139087     EISSN: None     Source Type: Journal    
DOI: 10.5021/ad.2012.24.1.39     Document Type: Article

References (21)

1. Spiegelman BM, Flier JS. Obesity and the regulation of energy balance. Cell 2001;104:531-543. (Pubitemid 32201948)
2. Spiegelman BM, Hu E, Kim JB, Brun R. PPAR gamma and the control of adipogenesis. Biochimie 1997;79:111-112.
3. Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell 1994;79:1147-1156.
4. Umek RM, Friedman AD, McKnight SL. CCAAT-enhancer binding protein: a component of a differentiation switch. Science 1991;251:288-292. (Pubitemid 21916874)
5. Yeh WC, Cao Z, Classon M, McKnight SL. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes Dev 1995;9:168-181.
6. Kim JB, Spiegelman BM. ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev 1996;10:1096-1107. (Pubitemid 26152851)
7. Ranganathan G, Unal R, Pokrovskaya I, Yao-Borengasser A, Phanavanh B, Lecka-Czernik B, et al. The lipogenic enzymes DGAT1, FAS, and LPL in adipose tissue: effects of obesity, insulin resistance, and TZD treatment. J Lipid Res 2006;47:2444-2450. (Pubitemid 44936106)
8. Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998;395:763-770. (Pubitemid 28485436)
9. Rosen BS, Cook KS, Yaglom J, Groves DL, Volanakis JE, Damm D, et al. Adipsin and complement factor D activity: an immune-related defect in obesity. Science 1989;244:1483-1487. (Pubitemid 19171684)
10. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993;259:87-91. (Pubitemid 23036092)
11. Ahima RS, Flier JS. Adipose tissue as an endocrine organ. Trends Endocrinol Metab 2000;11:327-332.
12. Sartipy P, Loskutoff DJ. Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc Natl Acad Sci USA 2003;100:7265-7270. (Pubitemid 36706427)
13. Hardie DG, Scott JW, Pan DA, Hudson ER. Management of cellular energy by the AMP-activated protein kinase system. FEBS Lett 2003;546:113-120. (Pubitemid 36782291)
14. Fryer LG, Carling D. AMP-activated protein kinase and the metabolic syndrome. Biochem Soc Trans 2005;33:362-366. (Pubitemid 40604373)
15. Kahn BB, Alquier T, Carling D, Hardie DG. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 2005;1:15-25. (Pubitemid 43960587)
16. Roche-VITEC. Vitamin U. Pig News Info 1990;11:329-330.
17. Gessler NN, Kharchenko LI, Pavlovskaia TE, Bykhovskii VIa. Radiation-protective effect of S-methylmethionine (vitamin U). Prikl Biokhim Mikrobiol 1996;32:666-668.
18. Tomiyama K, Nakata H, Sasa H, Arimura S, Nishio E, Watanabe Y. Wortmannin, a specific phosphatidylinositol 3-kinase inhibitor, inhibits adipocytic differentiation of 3T3-L1 cells. Biochem Biophys Res Commun 1995;212:263-269.
19. Towler MC, Hardie DG. AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res 2007;100:328-341.
20. Dolinsky VW, Dyck JR. Role of AMP-activated protein kinase in healthy and diseased hearts. Am J Physiol Heart Circ Physiol 2006;291: H2557-2569. (Pubitemid 44911033)
21. Hwang JT, Park IJ, Shin JI, Lee YK, Lee SK, Baik HW, et al. Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase. Biochem Biophys Res Commun 2005;338:694-699. (Pubitemid 41597699)