Characterization of early stage intermediates in the nucleation phase of Aβ aggregation

Biochemistry

Volumn 51, Issue 6, 2012, Pages 1070-1078

  Zhai, Jiali ^a   Lee, Tzong Hsien ^a   Small, David H ^b   Aguilar, Marie Isabel ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF TASMANIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AGGREGATION PATTERNS; AGGREGATION PROCESS; ALZHEIMER'S DISEASE; AMYLOID FIBRIL FORMATION; AMYLOID FORMATION; AMYLOID PLAQUES; DUAL POLARIZATION INTERFEROMETRY; EXPONENTIAL GROWTH PHASE; EXTRACELLULAR; FIBRIL ELONGATION; FORMATION PROCESS; HYDROPHOBIC SURFACES; NANOMETER LEVEL; POLYMERIZATION MODEL; REAL-TIME CHANGES; REAL-TIME INFORMATION; SILICON OXYNITRIDES;

AGGLOMERATION; DISEASES; GLYCOPROTEINS; HYDROPHOBICITY; SILICON NITRIDE; SURFACE CHEMISTRY;

NUCLEATION;

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; SILICON NITRIDE;

ARTICLE; CELL NUCLEUS; HYDROPHOBICITY; INTERFEROMETRY; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN STRUCTURE;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PEPTIDES; BIOSENSING TECHNIQUES; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN ARRAY ANALYSIS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RECOMBINANT PROTEINS; SURFACE PROPERTIES;

EID: 84863161484     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201871r     Document Type: Article

References (46)

1. Gandy, S. (2005) The role of cerebral amyloid-β accumulation in common forms of Alzheimer disease J. Clin. Invest. 115, 1121-1129 (Pubitemid 40629026)
2. Hardy, J. and Selkoe, D. J. (2002) The amyloid hypothesis of Alzheimer's Disease: progress and problems on the road to therapeutics Science 297, 353-356 (Pubitemid 34790756)
3. Hardy, J. A. and Higgins, G. A. (1992) Alzheimer's disease: the amyloid cascade hypothesis Science 256, 184-185
4. Chromy, B. A., Nowak, R. J., Lambert, M. P., Viola, K. L., Chang, L., Velasco, P. T., Jones, B. W., Fernandez, S. J., Lacor, P. N., Horowitz, P., Finch, C. E., Krafft, G. A., and Klein, W. L. (2003) Self-assembly of Abeta(1-42) into globular neurotoxins Biochemistry 42, 12749-12760
5. Demuro, A., Mina, E., Kayed, R., Milton, S. C., Parker, I., and Glabe, C. G. (2005) Calcium Dysregulation and Membrane Disruption as a Ubiquitous Neurotoxic Mechanism of Soluble Amyloid Oligomers J. Biol. Chem. 280, 17294-17300 (Pubitemid 41389198)
6. Glabe, C. G. (2006) Common mechanisms of amyloid oligomer pathogenesis in degenerative disease Neurobiol. Aging 27, 570-575 (Pubitemid 43290525)
7. Hartley, D. M., Walsh, D. M., Ye, C. P., Diehl, T., Vasquez, S., Vassilev, P. M., Teplow, D. B., and Selkoe, D. J. (1999) Protofibrillar Intermediates of Amyloid beta -Protein Induce Acute Electrophysiological Changes and Progressive Neurotoxicity in Cortical Neurons J. Neurosci. 19, 8876-8884 (Pubitemid 30226709)
8. Kayed, R., Sokolov, Y., Edmonds, B., McIntire, T. M., Milton, S. C., Hall, J. E., and Glabe, C. G. (2004) Permeabilization of Lipid Bilayers Is a Common Conformation-dependent Activity of Soluble Amyloid Oligomers in Protein Misfolding Diseases J. Biol. Chem. 279, 46363-46366 (Pubitemid 39518276)
9. Kakio, A., Nishimoto, S. i., Yanagisawa, K., Kozutsumi, Y., and Matsuzaki, K. (2002) Interactions of Amyloid -Protein with Various Gangliosides in Raft-Like Membranes: Importance of GM1 Ganglioside-Bound Form as an Endogenous Seed for Alzheimer Amyloid Biochemistry 41, 7385-7390 (Pubitemid 34602456)
10. Subasinghe, S., Unabia, S., Barrow, C. J., Mok, S. S., Aguilar, M. I., and Small, D. H. (2003) Cholesterol is necessary both for the toxic effect of Abeta peptides on vascular smooth muscle cells and for Abeta binding to vascular smooth muscle cell membranes J. Neurochem. 84, 471-479 (Pubitemid 36182246)
11. Yip, C. M., Darabie, A. A., and McLaurin, J. (2002) Abeta42-peptide assembly on lipid bilayers J. Mol. Biol. 318, 97-107
12. Yip, C. M. and McLaurin, J. (2001) Amyloid-beta peptide assembly: a critical step in fibrillogenesis and membrane disruption Biophys. J. 80, 1359-1371 (Pubitemid 32182160)
13. Losic, D., Martin, L. L., Aguilar, M. I., and Small, D. H. (2006) Beta-amyloid fibril formation is promoted by step edges of highly oriented pyrolytic graphite Biopolymers 84, 519-526 (Pubitemid 44519211)
14. Wang, Q., Shah, N., Zhao, J., Wang, C., Zhao, C., Liu, L., Li, L., Zhou, F., and Zheng, J. (2011) Structural, morphological, and kinetic studies of beta-amyloid peptide aggregation on self-assembled monolayers Phys. Chem. Chem. Phys. 13, 15200-15210
15. Zhao, J., Wang, Q., Liang, G., and Zheng, J. Molecular Dynamics Simulations of Low-Ordered Alzheimer beta-Amyloid Oligomers from Dimer to Hexamer on Self-Assembled Monolayers, Langmuir, in press.
16. Serpell, L. C. (2000) Alzheimer's amyloid fibrils: structure and assembly Biochim. Biophys. Acta, Mol. Basis Dis. 1502, 16-30 (Pubitemid 30433852)
17. Losic, D., Martin, L. L., Mechler, A., Aguilar, M. I., and Small, D. H. (2006) High resolution scanning tunnelling microscopy of the beta-amyloid protein (Abeta1-40) of Alzheimer's disease suggests a novel mechanism of oligomer assembly J. Struct. Biol. 155, 104-110 (Pubitemid 43867319)
18. Arimon, M., Diez-Perez, I., Kogan, M. J., Durany, N., Giralt, E., Sanz, F., and Fernandez-Busquets, X. (2005) Fine structure study of Abeta1-42 fibrillogenesis with atomic force microscopy FASEB J. 19, 1344-1346 (Pubitemid 41113744)
19. Ban, T., Morigaki, K., Yagi, H., Kawasaki, T., Kobayashi, A., Yuba, S., Naiki, H., and Goto, Y. (2006) Real-time and Single Fibril Observation of the Formation of Amyloid beta Spherulitic Structures J. Biol. Chem. 281, 33677-33683 (Pubitemid 46036746)
20. Sunde, M., Serpell, L. C., Bartlam, M., Fraser, P. E., Pepys, M. B., and Blake, C. C. F. (1997) Common core structure of amyloid fibrils by synchrotron X-ray diffraction J. Mol. Biol. 273, 729-739 (Pubitemid 27488813)
21. Jarrett, J. T. and Lansbury, P. T., Jr. (1993) Seeding one-dimensional crystallization of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie? Cell 73, 1055-1058 (Pubitemid 23180480)
22. Cannon, M. J., Williams, A. D., Wetzel, R., and Myszka, D. G. (2004) Kinetic analysis of beta-amyloid fibril elongation Anal. Biochem. 328, 67-75 (Pubitemid 38479619)
23. Esler, W. P., Stimson, E. R., Jennings, J. M., Vinters, H. V., Ghilardi, J. R., Lee, J. P., Mantyh, P. W., and Maggio, J. E. (2000) Alzheimer's Disease Amyloid Propagation by a Template-Dependent Dock-Lock Mechanism Biochemistry 39, 6288-6295 (Pubitemid 30347132)
24. Hasegawa, K., Ono, K., Yamada, M., and Naiki, H. (2002) Kinetic Modeling and Determination of Reaction Constants of Alzheimer's [beta]-Amyloid Fibril Extension and Dissociation Using Surface Plasmon Resonance Biochemistry 41, 13489-13498 (Pubitemid 35332684)
25. Aguilar, M. I. and Small, D. H. (2005) Surface plasmon resonance for the analysis of beta-amyloid interactions and fibril formation in Alzheimer's disease research Neurotox. Res. 7, 17-27
26. Freeman, N. J., Peel, L. L., Swann, M. J., Cross, G. H., Reeves, A., Brand, S., and Lu, J. R. (2004) Real time, high resolution studies of protein adsorption and structure at the solid-liquid interface using dual polarization interferometry J. Phys.: Condens. Matter 16, S2493-S2496
27. Lee, T., Hall, K., Swann, M., Popplewell, J., Unabia, S., Park, Y., Hahm, K., and Aguilar, M. (2010) The membrane insertion of helical antimicrobial peptides from the N-terminus of Helicobacter pylori risbosomal protein L1 Biochim. Biophys. Acta 1798, 544-557
28. Lee, T. H., Heng, C., Swann, M. J., Gehman, J. D., Separovic, F., and Aguilar, M. I. (2010) Real-time quantitative analysis of lipid disordering by aurein 1.2 during membrane adsorption, destabilisation and lysis Biochim. Biophys. Acta 1798, 1977-1986
29. Sheu, B. C., Lin, Y. H., Lin, C. C., Lee, A. S., Chang, W. C., Wu, J. H., Tsai, J. C., and Lin, S. (2010) Significance of the pH-induced conformational changes in the structure of C-reactive protein measured by dual polarization interferometry Biosens. Bioelectron. 26, 822-827
30. Swann, M. J., Peel, L. L., Carrington, S., and Freeman, N. J. (2004) Dual-polarization interferometry: an analytical technique to measure changes in protein structure in real time, to determine the stoichiometry of binding events, and to differentiate between specific and nonspecific interactions Anal. Biochem. 329, 190-198 (Pubitemid 38684155)
31. Hirst, D., Lee, T., Unabia, S., Swann, M., Park, Y., Hahm, K., and Aguilar, M. (2011) The effect of acyl chain structure and bilayer phase state on the binding and insertion of HPA3 onto a supported lipid bilayer Eur. Biophys. J. 40, 503-514
32. Nilsson, M. R. (2004) Techniques to study amyloid fibril formation in vitro Methods 34, 151-160 (Pubitemid 38993215)
33. Cross, G. H., Reeves, A. A., Brand, S., Popplewell, J. F., Peel, L. L., Swann, M. J., and Freeman, N. J. (2003) A new quantitative optical biosensor for protein characterisation Biosens. Bioelectron. 19, 383-390 (Pubitemid 37419962)
34. Cross, G. H., Reeves, A. A., Brand, S., Swann, M. J., Peel, L. L., Freeman, N. J., and Lu, J. R. (2004) The metrics of surface adsorbed small molecules on the Young's fringe dual-slab waveguide interferometer J. Phys. D: Appl. Phys. 37, 74-80
35. Blackley, H. K. L., Sanders, G. H. W., Davies, M. C., Roberts, C. J., Tendler, S. J. B., and Wilkinson, M. J. (2000) In-situ atomic force microscopy study of β-amyloid fibrillization J. Mol. Biol. 298, 833-840
36. Kowalewski, T. and Holtzman, D. M. (1999) In situ atomic force microscopy study of Alzheimer's beta-amyloid peptide on different substrates: new insights into mechanism of β-sheet formation Proc. Natl. Acad. Sci. U. S. A. 96, 3688-3693 (Pubitemid 29168971)
37. Wang, Z., Zhou, C., Wang, C., Wan, L., Fang, X., and Bai, C. (2003) AFM and STM study of [beta]-amyloid aggregation on graphite Ultramicroscopy 97, 73-79 (Pubitemid 36683282)
38. Mastrangelo, I. A., Ahmed, M., Sato, T., Liu, W., Wang, C., Hough, P., and Smith, S. O. (2006) High-resolution Atomic Force Microscopy of Soluble A[beta]42 Oligomers J. Mol. Biol. 358, 106-119
39. Klug, G. M., Losic, D., Subasinghe, S. S., Aguilar, M. I., Martin, L. L., and Small, D. H. (2003) Beta-amyloid protein oligomers induced by metal ions and acid pH are distinct from those generated by slow spontaneous ageing at neutral pH Eur. J. Biochem. 270, 4282-4293 (Pubitemid 37340346)
40. Farfield. (2007) Measuring early-stage β-amyloid aggregation using dual polarisation interferometry, Application Note 004.
41. Ma, X., Liu, L., Mao, X., Niu, L., Deng, K., Wu, W., Li, Y., Yang, Y., and Wang, C. (2009) Amyloid beta (1-42) folding multiplicity and single-molecule binding behavior studied with STM J. Mol. Biol. 388, 894-901
42. Tycko, R. (2006) Molecular structure of amyloid fibrils: insights from solid-state NMR Q. Rev. Biophys. 39, 1-55 (Pubitemid 44566373)
43. Matsumura, S., Shinoda, K., Yamada, M., Yokojima, S., Inoue, M., Ohnishi, T., Shimada, T., Kikuchi, K., Masui, D., Hashimoto, S., Sato, M., Ito, A., Akioka, M., Takagi, S., Nakamura, Y., Nemoto, K., Hasegawa, Y., Takamoto, H., Inoue, H., Nakamura, S., Nabeshima, Y., Teplow, D. B., Kinjo, M., and Hoshi, M. (2011) Two distinct amyloid beta-protein (Abeta) assembly pathways leading to oligomers and fibrils identified by combined fluorescence correlation spectroscopy, morphology, and toxicity analyses J. Biol. Chem. 286, 11555-11562
44. Sanchez, L., Madurga, S., Pukala, T., Vilaseca, M., Lopez-Iglesias, C., Robinson, C. V., Giralt, E., and Carulla, N. (2011) Abeta40 and Abeta42 amyloid fibrils exhibit distinct molecular recycling properties J. Am. Chem. Soc. 133, 6505-6508
45. Moores, B., Drolle, E., Attwood, S. J., Simons, J., and Leonenko, Z. (2011) Effect of surfaces on amyloid fibril formation PLoS One 6, e25954
46. Zhao, J., Wang, Q., Liang, G., and Zheng, J. (2011) Molecular Dynamics Simulations of Low-Ordered Alzheimer beta-Amyloid Oligomers from Dimer to Hexamer on Self-Assembled Monolayers Langmuir 27, 14876-14887