Real-time PCR and high-resolution melt analysis for rapid detection of Mycobacterium leprae drug resistance mutations and strain types

Journal of Clinical Microbiology

Volumn 50, Issue 3, 2012, Pages 742-753

  Li, Wei ^a   Matsuoka, Masanori ^b   Kai, Masanori ^b   Thapa, Pratibha ^c   Khadge, Saraswoti ^c   Hagge, Deanna A ^c   Brennan, Patrick J ^a   Vissa, Varalakshmi ^a  

^a Department of Ecosystem Science and Sustainability   (United States)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c Anandaban Leprosy Hospital   (Nepal)

Author keywords

[No Author keywords available]

Indexed keywords

DAPSONE; QUINOLONE DERIVATIVE; RIFAMPICIN;

ACCURACY; ARTICLE; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; CODON; CONTROLLED STUDY; FOLP1 GENE; GENE; GENE MUTATION; GENOTYPE; GYRA GENE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MOUSE; MYCOBACTERIUM LEPRAE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REAL TIME POLYMERASE CHAIN REACTION HIGH RESOLUTION MELT; RPOB GENE; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; VALIDITY;

ANIMALS; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; HUMANS; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR DIAGNOSTIC TECHNIQUES; MUTATION, MISSENSE; MYCOBACTERIUM LEPRAE; POLYMORPHISM, SINGLE NUCLEOTIDE; REAL-TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; TRANSITION TEMPERATURE;

EID: 84863148656     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.05183-11     Document Type: Article

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