Adipose tissue-derived stem cell-seeded small intestinal submucosa for tunica albuginea grafting and reconstruction

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 6, 2012, Pages 2090-2095

  Ma, Limin ^a   Yang, Yijun ^a   Sikka, Suresh C ^a,b   Kadowitz, Philip J ^b   Ignarro, Louis J ^c   Abdel Mageed, Asim B ^a,b   Hellstrom, Wayne J G ^a  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Incision and grafting procedures; Penile surgery; Peyronie's disease

Indexed keywords

BETA1 INTEGRIN; CD45 ANTIGEN; ENDOGLIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBROBLAST GROWTH FACTOR 2; INOSINATE DEHYDROGENASE; NEURONAL NITRIC OXIDE SYNTHASE; THY 1 ANTIGEN; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN;

ADIPOSE DERIVED STEM CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAVERNOUS NERVE STIMULATION; CELL STRUCTURE; CONTROLLED STUDY; CORPUS CAVERNOSUM; CROSS-SECTIONAL STUDY; CYTOPLASM; DOWN REGULATION; FEASIBILITY STUDY; FIBROSIS; FOREIGN BODY REACTION; INTRACRANIAL PRESSURE; MALE; MEAN ARTERIAL PRESSURE; NERVE STIMULATION; NONHUMAN; PENIS ERECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMALL INTESTINE MUCOSA; STEM CELL TRANSPLANTATION; TUNICA ALBUGINEA; UPREGULATION;

ADIPOSE TISSUE; ANIMALS; BROMODEOXYURIDINE; CELLS, CULTURED; FIBROSIS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; INTESTINAL MUCOSA; INTESTINE, SMALL; ISOENZYMES; MALE; NITRIC OXIDE SYNTHASE; PENILE ERECTION; PENIS; RATS; RECONSTRUCTIVE SURGICAL PROCEDURES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STAINING AND LABELING; STEM CELL TRANSPLANTATION; STEM CELLS; SUS SCROFA;

ANIMALIA; RATTUS; SUS;

EID: 84863134804     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1113810109     Document Type: Article

References (27)

1. Lue TF (2000) Erectile dysfunction. N Engl J Med 342:1802-1813.
2. Leungwattanakij S, Bivalacqua TJ, Yang DY, Hyun JS, Hellstrom WJ (2003) Comparison of cadaveric pericardial, dermal, vein, and synthetic grafts for tunica albuginea substitution using a rat model. BJU Int 92:119-124. (Pubitemid 36843041)
3. Gur S, Ma L, Hellstrom WJ (2011) Current status and new developments in Peyronie's disease: Medical, minimally invasive and surgical treatment options. Expert Opin Pharmacother 12:931-944.
4. Kadioglu A, et al. (2007) Graft materials in Peyronie's disease surgery: A comprehensive review. J Sex Med 4:581-595. (Pubitemid 46779294)
5. Phinney DG, Prockop DJ (2007) Mesenchymal stem/multi-potent stromal cells (mscs): The state of transdifferentiation and modes of tissue repair - current views. Stem Cells 25:2896-2902. (Pubitemid 350127874)
6. Gong Z, Niklason LE (2008) Small-diameter human vessel wall engineered from bone marrow-derived mesenchymal stem cells (hMSCs). FASEB J 22:1635-1648. (Pubitemid 351811442)
7. Bernardo ME, et al. (2007) Optimization of in vitro expansion of human multipotent mesenchymal stromal cells for cell-therapy approaches: Further insights in the search for a fetal calf serum substitute. J Cell Physiol 211:121-130. (Pubitemid 46363901)
8. Lazarus HM, et al. (2005) Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients. Biol Blood Marrow Transplant 11:389-398. (Pubitemid 40542932)
9. Yamada Y, et al. (2004) Autogenous injectable bone for regeneration with mesenchymal stem cells and platelet-rich plasma: Tissue-engineered bone regeneration. Tissue Eng 10:955-964. (Pubitemid 38880414)
10. Knoll LD (2007) Use of small intestinal submucosa graft for the surgical management of Peyronie's disease. J Urol 178:2474-2478, discussion 2478.
11. Eltahawy EA, Virasoro R, McCammon KA, Schlossberg SM, Jordan GH (2006) Management of Peyronie's disease using dermal or porcine small intestinal submucosa (SIS) grafts. J Urol 175:suppl 321, abstract 996.
12. John T, Bandi G, Santucci R (2006) Porcine small intestinal submucosa is not an ideal graft material for Peyronie's disease surgery. J Urol 176:1025-1028, discussion 1029.
13. Sievert KD, Tanagho EA (2000) Organ-specific acellular matrix for reconstruction of the urinary tract. World J Urol 18:19-25.
14. Seong JM, et al. (2010) Stem cells in bone tissue engineering. Biomed Mater 5:062001.
15. Lin CS, et al. (2010) Defining adipose tissue-derived stem cells in tissue and in culture. Histol Histopathol 25:807-815.
16. Nakagami H, et al. (2006) Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy. J Atheroscler Thromb 13:77-81.
17. Albersen M, et al. (2010) Injections of adipose tissue-derived stem cells and stem cell lysate improve recovery of erectile function in a rat model of cavernous nerve injury. J Sex Med 7:3331-3340.
18. Kovanecz I, et al. (2008) Chronic daily tadalafil prevents the corporal fibrosis and veno-occlusive dysfunction that occurs after cavernosal nerve resection. BJU Int 101: 203-210. (Pubitemid 350294044)
19. Lin G, et al. (2010) Pentoxifylline attenuates transforming growth factor-beta1- stimulated elastogenesis in human tunica albuginea-derived fibroblasts part 2: Interference in a TGF-beta1/Smad-dependent mechanism and downregulation of AAT1. J Sex Med 7:1787-1797.
20. Kilroy GE, et al. (2007) Cytokine profile of human adipose-derived stem cells: Expression of angiogenic, hematopoietic, and pro-inflammatory factors. J Cell Physiol 212:702-709. (Pubitemid 47271882)
21. Lee EY, et al. (2009) Hypoxia-enhanced wound-healing function of adipose-derived stem cells: Increase in stem cell proliferation and up-regulation of VEGF and bFGF. Wound Repair Regen 17:540-547.
22. Cai L, et al. (2007) Suppression of hepatocyte growth factor production impairs the ability of adipose-derived stem cells to promote ischemic tissue revascularization. Stem Cells 25:3234-3243. (Pubitemid 350294449)
23. Kane AJ, et al. (2001) Inducible nitric oxide synthase (iNOS) activity promotes ischaemic skin flap survival. Br J Pharmacol 132:1631-1638. (Pubitemid 32397954)
24. Kendirci M, et al. (2005) Poly(Adenosine diphosphate-ribose) polymerase inhibition preserves erectile function in rats after cavernous nerve injury. J Urol 174:2054-2059. (Pubitemid 41547023)
25. Bivalacqua TJ, et al. (2000) A rat model of Peyronie's disease associated with a decrease in erectile activity and an increase in inducible nitric oxide synthase protein expression. J Urol 163:1992-1998. (Pubitemid 30366800)
26. Jesmin S, et al. (2003) Diminished penile expression of vascular endothelial growth factor and its receptors at the insulin-resistant stage of a type II diabetic rat model: A possible cause for erectile dysfunction in diabetes. J Mol Endocrinol 31:401-418. (Pubitemid 38054513)
27. Donnenberg VS, et al. (2010) Localization of CD44 and CD90 positive cells to the invasive front of breast tumors. Cytometry B Clin Cytom 78:287-301.