Pentoxifylline attenuates transforming growth factor-β1-stimulated elastogenesis in human Tunica albuginea-derived fibroblasts part 2: Interference in a TGF-β1/smad-dependent mechanism and downregulation of AAT1

Journal of Sexual Medicine

Volumn 7, Issue 5, 2010, Pages 1787-1797

  Lin, Guiting ^a   Shindel, Alan W ^a   Banie, Lia ^a   Ning, Hongxiu ^a   Huang, Yun Ching ^a   Liu, Gang ^a   Lin, Ching Shwun ^a   Lue, Tom F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alpha Antitrypsin; Elastin; Pentoxifylline; Peyronie's Disease; Smads; Tunica Albuginea

Indexed keywords

ALPHA 1 ANTITRYPSIN; COLLAGEN; ELASTIN; MESSENGER RNA; PENTOXIFYLLINE; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD6 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; C3ORF15 PROTEIN, HUMAN; CARRIER PROTEIN; PHOSPHODIESTERASE INHIBITOR; SMAD PROTEIN;

ARTICLE; ATTENUATION; CELL CULTURE; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MONOTHERAPY; PEYRONIE DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TIME; TUNICA ALBUGINEA; UPREGULATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ELASTIC TISSUE; GENETICS; METABOLISM; PATHOPHYSIOLOGY; PENIS; PHYSIOLOGY;

BLOTTING, WESTERN; CARRIER PROTEINS; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ELASTIC TISSUE; ELASTIN; FIBROBLASTS; GENE EXPRESSION; HUMANS; MALE; PENILE INDURATION; PENIS; PENTOXIFYLLINE; PHOSPHODIESTERASE INHIBITORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77953592469     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2010.01749.x     Document Type: Article

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