Characterization of splice variants of the genes encoding human mitochondrial HMG-CoA lyase and HMG-CoA synthase, the main enzymes of the ketogenesis pathway

Molecular Biology Reports

Volumn 39, Issue 4, 2012, Pages 4777-4785

  Puisac, Beatriz ^a   Ramos, Mónica ^a   Arnedo, María ^a   Menao, Sebastián ^a   Gil Rodríguez, María Concepción ^a   Teresa Rodrigo, María Esperanza ^a   Pié, Angeles ^a   De Karam, Juan Carlos ^a   Wesselink, Jan Jaap ^b,c   Giménez, Ignacio ^a   Ramos, Feliciano J ^a   Casals, Nuria ^d   Gómez Puertas, Paulino ^c   Hegardt, Fausto G ^e   Pié, Juan ^a  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b Biomol Informatics SL C/Faraday   (Spain)

^c CENTRO DE BIOLOGÍA MOLECULAR SEVERO OCHOA   (Spain)

^d UNIVERSITAT INTERNACIONAL DE CATALUNYA   (Spain)

^e UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Alternative splicing; HMGCL; HMGCS2; Ketone bodies

Indexed keywords

COMPLEMENTARY DNA; HYDROXYMETHYLGLUTARYL COENZYME A LYASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; KETONE; MESSENGER RNA; PROTEIN VARIANT; 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A LYASE; ISOENZYME; KETONE BODY; LYASE;

ALTERNATIVE RNA SPLICING; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; DNA SEQUENCE; DOWN REGULATION; EMBRYO; ENZYME INHIBITION; EXON; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HMGCL GENE; HMGCS2 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; KETOGENESIS; MITOCHONDRIAL GENE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; BIOLOGY; BIOSYNTHESIS; CELL STRAIN HEK293; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; MITOCHONDRION; PROTEIN SECONDARY STRUCTURE; REAL TIME POLYMERASE CHAIN REACTION;

EUKARYOTA; PROKARYOTA;

ALTERNATIVE SPLICING; BIOSYNTHETIC PATHWAYS; BLOTTING, WESTERN; COMPUTATIONAL BIOLOGY; HEK293 CELLS; HUMANS; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; ISOENZYMES; KETONE BODIES; MITOCHONDRIA; OXO-ACID-LYASES; PROTEIN STRUCTURE, SECONDARY; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84863113520     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-011-1270-8     Document Type: Article

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