메뉴 건너뛰기




Volumn 119, Issue 2, 2012, Pages 131-138

Add-on aliskiren elicits stronger renoprotection than high-dose valsartan in type 2 diabetic KKAy mice that do not respond to low-dose valsartan

Author keywords

Aliskiren; Diabetic nephropathy; Valsartan

Indexed keywords

ALISKIREN; ANGIOTENSIN II; DESMIN; GLUCOSE; MESSENGER RNA; PROTEIN P21; RENIN; VALSARTAN;

EID: 84863103139     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.12031FP     Document Type: Article
Times cited : (14)

References (46)
  • 1
    • 79951639177 scopus 로고    scopus 로고
    • Nebivolol attenuates redox-sensitive glomerular and tubular mediated proteinuria in obese rats
    • Habibi J, Hayden MR, Sowers JR, Pulakat L, Tilmon RD, Manrique C, et al. Nebivolol attenuates redox-sensitive glomerular and tubular mediated proteinuria in obese rats. Endocrinology. 2011;152:659-668.
    • (2011) Endocrinology , vol.152 , pp. 659-668
    • Habibi, J.1    Hayden, M.R.2    Sowers, J.R.3    Pulakat, L.4    Tilmon, R.D.5    Manrique, C.6
  • 2
    • 79955771730 scopus 로고    scopus 로고
    • The proximal tubule in the pathophysiology of the diabetic kidney
    • Vallon V. The proximal tubule in the pathophysiology of the diabetic kidney. Am J Physiol Regul Integr Comp Physiol. 2011;300:R1009-R1022.
    • (2011) Am J Physiol Regul Integr Comp Physiol , vol.300
    • Vallon, V.1
  • 3
    • 85018166097 scopus 로고    scopus 로고
    • Short-term calorie restriction in early life attenuates the development of proteinuria but not glucose intolerance in type 2 diabetic oletf rats
    • In press
    • Nakano D, Diah S, Kitada K, Hitomi H, Mori H, Masaki T, et al. Short-term calorie restriction in early life attenuates the development of proteinuria but not glucose intolerance in type 2 diabetic oletf rats. ISRN Endocrinology. In press.
    • ISRN Endocrinology
    • Nakano, D.1    Diah, S.2    Kitada, K.3    Hitomi, H.4    Mori, H.5    Masaki, T.6
  • 4
    • 79959702777 scopus 로고    scopus 로고
    • Chronic kidney disease growth factors in renal fibrosis
    • Boor P, Floege J. Chronic kidney disease growth factors in renal fibrosis. Clin Exp Pharmacol Physiol. 2011;38:391-400.
    • (2011) Clin Exp Pharmacol Physiol , vol.38 , pp. 391-400
    • Boor, P.1    Floege, J.2
  • 5
    • 77958515296 scopus 로고    scopus 로고
    • Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria: Effect of angiotensin II blockade
    • Ihara G, Kiyomoto H, Kobori H, Nagai Y, Ohashi N, Hitomi H, et al. Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria: effect of angiotensin II blockade. J Hypertens. 2010;28:2289-2298.
    • (2010) J Hypertens , vol.28 , pp. 2289-2298
    • Ihara, G.1    Kiyomoto, H.2    Kobori, H.3    Nagai, Y.4    Ohashi, N.5    Hitomi, H.6
  • 6
    • 78049314926 scopus 로고    scopus 로고
    • Inhibition of the renal renin-angiotensin system and reno-protection by pitavastatin in type 1 diabetes
    • Toba H, Mitani T, Takahashi T, Imai N, Serizawa R, Wang J, et al. Inhibition of the renal renin-angiotensin system and reno-protection by pitavastatin in type 1 diabetes. Clin Exp Pharmacol Physiol. 2010;37:1064-1070.
    • (2010) Clin Exp Pharmacol Physiol , vol.37 , pp. 1064-1070
    • Toba, H.1    Mitani, T.2    Takahashi, T.3    Imai, N.4    Serizawa, R.5    Wang, J.6
  • 7
    • 77957256321 scopus 로고    scopus 로고
    • Microalbuminuria as a risk factor: The influence of renin-angiotensin system blockade
    • Menne J, Chatzikyrkou C, Haller H. Microalbuminuria as a risk factor: the influence of renin-angiotensin system blockade. J Hypertens. 2010;28:1983-1994.
    • (2010) J Hypertens , vol.28 , pp. 1983-1994
    • Menne, J.1    Chatzikyrkou, C.2    Haller, H.3
  • 8
    • 78651266379 scopus 로고    scopus 로고
    • Effects of verapamil added-on trandolapril therapy in hypertensive type 2 diabetes patients with microalbuminuria: The BENEDICT-B randomized trial
    • Ruggenenti P, Fassi A, Ilieva AP, Iliev IP, Chiurchiu C, Rubis N, et al. Effects of verapamil added-on trandolapril therapy in hypertensive type 2 diabetes patients with microalbuminuria: the BENEDICT-B randomized trial. J Hypertens. 2011;29:207-216.
    • (2011) J Hypertens , vol.29 , pp. 207-216
    • Ruggenenti, P.1    Fassi, A.2    Ilieva, A.P.3    Iliev, I.P.4    Chiurchiu, C.5    Rubis, N.6
  • 12
    • 2942536127 scopus 로고    scopus 로고
    • Losartan ameliorates progression of glomerular structural changes in diabetic KKAy mice
    • DOI 10.1016/j.lfs.2004.01.022, PII S0024320504003285
    • Sasaki M, Uehara S, Ohta H, Taguchi K, Kemi M, Nishikibe M, et al. Losartan ameliorates progression of glomerular structural changes in diabetic KKAy mice. Life Sci. 2004;75:869-880. (Pubitemid 38737423)
    • (2004) Life Sciences , vol.75 , Issue.7 , pp. 869-880
    • Sasaki, M.1    Uehara, S.2    Ohta, H.3    Taguchi, K.4    Kemi, M.5    Nishikibe, M.6    Matsumoto, H.7
  • 13
    • 69449108644 scopus 로고    scopus 로고
    • Mineralocorticoid receptor blockade and calcium channel blockade have different renoprotective effects on glomerular and interstitial injury in rats
    • Du J, Fan YY, Hitomi H, Kiyomoto H, Kimura S, Kong CZ, et al. Mineralocorticoid receptor blockade and calcium channel blockade have different renoprotective effects on glomerular and interstitial injury in rats. Am J Physiol Renal Physiol. 2009;297: F802-F808.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Du, J.1    Fan, Y.Y.2    Hitomi, H.3    Kiyomoto, H.4    Kimura, S.5    Kong, C.Z.6
  • 14
    • 78651317494 scopus 로고    scopus 로고
    • Effects of mineralocorticoid receptor blockade on glucocorticoid- Induced renal injury in adrenalectomized rats
    • Rafiq K, Nakano D, Ihara G, Hitomi H, Fujisawa Y, Ohashi N, et al. Effects of mineralocorticoid receptor blockade on glucocorticoid- induced renal injury in adrenalectomized rats. J Hypertens. 2011;29:290-298.
    • (2011) J Hypertens , vol.29 , pp. 290-298
    • Rafiq, K.1    Nakano, D.2    Ihara, G.3    Hitomi, H.4    Fujisawa, Y.5    Ohashi, N.6
  • 15
    • 79951587283 scopus 로고    scopus 로고
    • Aldosterone/mineralocorticoid receptor stimulation induces cellular senescence in the kidney
    • Fan YY, Kohno M, Hitomi H, Kitada K, Fujisawa Y, Yatabe J, et al. Aldosterone/mineralocorticoid receptor stimulation induces cellular senescence in the kidney. Endocrinology. 2011;152: 680-688.
    • (2011) Endocrinology , vol.152 , pp. 680-688
    • Fan, Y.Y.1    Kohno, M.2    Hitomi, H.3    Kitada, K.4    Fujisawa, Y.5    Yatabe, J.6
  • 16
    • 84857049702 scopus 로고    scopus 로고
    • Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice
    • Nakano D, Lei B, Kitada K, Hitomi H, Kobori H, Mori H, et al. Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice. Am J Hypertens. 2012;25:354-358.
    • (2012) Am J Hypertens , vol.25 , pp. 354-358
    • Nakano, D.1    Lei, B.2    Kitada, K.3    Hitomi, H.4    Kobori, H.5    Mori, H.6
  • 18
    • 0036707873 scopus 로고    scopus 로고
    • Renal interstitial fluid angiotensin I and angiotensin II concentrations during local angiotensin-converting enzyme inhibition
    • DOI 10.1097/01.ASN.0000026610.48842.CB
    • Nishiyama A, Seth DM, Navar LG. Renal interstitial fluid angiotensin I and angiotensin II concentrations during local angiotensin- converting enzyme inhibition. J Am Soc Nephrol. 2002; 13:2207-2212. (Pubitemid 34925230)
    • (2002) Journal of the American Society of Nephrology , vol.13 , Issue.9 , pp. 2207-2212
    • Nishiyama, A.1    Seth, D.M.2    Navar, L.G.3
  • 19
    • 58149216612 scopus 로고    scopus 로고
    • Strict angiotensin blockade prevents the augmentation of intrarenal angiotensin II and podocyte abnormalities in type 2 diabetic rats with microalbuminuria
    • Nishiyama A, Nakagawa T, Kobori H, Nagai Y, Okada N, Konishi Y, et al. Strict angiotensin blockade prevents the augmentation of intrarenal angiotensin II and podocyte abnormalities in type 2 diabetic rats with microalbuminuria. J Hypertens. 2008;26: 1849-1859.
    • (2008) J Hypertens , vol.26 , pp. 1849-1859
    • Nishiyama, A.1    Nakagawa, T.2    Kobori, H.3    Nagai, Y.4    Okada, N.5    Konishi, Y.6
  • 21
    • 79952427804 scopus 로고    scopus 로고
    • Aliskiren reduces albuminuria and oxidative stress, and elevates glomerular filtration rates in Japanese patients with advanced diabetic nephropathy
    • Ogawa S, Nako K, Okamura M, Senda M, Mori T, Ito S. Aliskiren reduces albuminuria and oxidative stress, and elevates glomerular filtration rates in Japanese patients with advanced diabetic nephropathy. Hypertens Res. 2011;34:400-401.
    • (2011) Hypertens Res , vol.34 , pp. 400-401
    • Ogawa, S.1    Nako, K.2    Okamura, M.3    Senda, M.4    Mori, T.5    Ito, S.6
  • 23
    • 30944466929 scopus 로고    scopus 로고
    • Enhanced renoprotective effects of ultrahigh doses of irbesartan in patients with type 2 diabetes and microalbuminuria
    • DOI 10.1111/j.1523-1755.2005.00511.x, PII 4494697
    • Rossing K, Schjoedt KJ, Jensen BR, Boomsma F, Parving HH. Enhanced renoprotective effects of ultrahigh doses of irbesartan in patients with type 2 diabetes and microalbuminuria. Kidney Int. 2005;68:1190-1198. (Pubitemid 43246436)
    • (2005) Kidney International , vol.68 , Issue.3 , pp. 1190-1198
    • Rossing, K.1    Schjoedt, K.J.2    Jensen, B.R.3    Boomsma, F.4    Parving, H.-H.5
  • 25
    • 9644287897 scopus 로고    scopus 로고
    • Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption
    • DOI 10.1097/01.ASN.0000146686.35541.29
    • Azizi M, Menard J, Bissery A, Guyenne TT, Bura-Riviere A, Vaidyanathan S, et al. Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption. J Am Soc Nephrol. 2004;15: 3126-3133. (Pubitemid 39578845)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.12 , pp. 3126-3133
    • Azizi, M.1    Menard, J.2    Bissery, A.3    Guyenne, T.-T.4    Bura-Riviere, A.5    Vaidyanathan, S.6    Camisasca, R.P.7
  • 26
    • 34548818515 scopus 로고    scopus 로고
    • Hormonal and hemodynamic effects of aliskiren and valsartan and their combination in sodium-replete normotensive individuals
    • Azizi M, Menard J, Bissery A, Guyene TT, Bura-Riviere A. Hormonal and hemodynamic effects of aliskiren and valsartan and their combination in sodium-replete normotensive individuals. Clin J Am Soc Nephrol. 2007;2:947-955.
    • (2007) Clin J Am Soc Nephrol , vol.2 , pp. 947-955
    • Azizi, M.1    Menard, J.2    Bissery, A.3    Guyene, T.T.4    Bura-Riviere, A.5
  • 27
    • 33646075100 scopus 로고    scopus 로고
    • Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan
    • Fan YY, Baba R, Nagai Y, Miyatake A, Hosomi N, Kimura S, et al. Augmentation of intrarenal angiotensin II levels in uninephrectomized aldosterone/salt-treated hypertensive rats; renoprotective effects of an ultrahigh dose of olmesartan. Hypertens Res. 2006;29:169-178.
    • (2006) Hypertens Res , vol.29 , pp. 169-178
    • Fan, Y.Y.1    Baba, R.2    Nagai, Y.3    Miyatake, A.4    Hosomi, N.5    Kimura, S.6
  • 28
    • 78349289577 scopus 로고    scopus 로고
    • A reduction of unilateral ureteral obstruction-induced renal fibrosis by a therapy combining valsartan with aliskiren
    • Wu WP, Chang CH, Chiu YT, Ku CL, Wen MC, Shu KH, et al. A reduction of unilateral ureteral obstruction-induced renal fibrosis by a therapy combining valsartan with aliskiren. Am J Physiol Renal Physiol. 2010;299:F929-F941.
    • (2010) Am J Physiol Renal Physiol , vol.299
    • Wu, W.P.1    Chang, C.H.2    Chiu, Y.T.3    Ku, C.L.4    Wen, M.C.5    Shu, K.H.6
  • 29
    • 77954383099 scopus 로고    scopus 로고
    • Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice
    • Dong YF, Liu L, Lai ZF, Yamamoto E, Kataoka K, Nakamura T, et al. Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice. J Hypertens. 2010;28: 1554-1565.
    • (2010) J Hypertens , vol.28 , pp. 1554-1565
    • Dong, Y.F.1    Liu, L.2    Lai, Z.F.3    Yamamoto, E.4    Kataoka, K.5    Nakamura, T.6
  • 30
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res. 1961;25:585-621.
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 34
    • 77951950634 scopus 로고    scopus 로고
    • Pharmacokinetics and bioequivalence study of three oral formulations of valsartan 160 mg: A single-dose, randomized, open-label, three-period crossover comparison in healthy indian male volunteers
    • Iqbal M, Khuroo A, Batolar LS, Tandon M, Monif T, Sharma PL. Pharmacokinetics and bioequivalence study of three oral formulations of valsartan 160 mg: a single-dose, randomized, open-label, three-period crossover comparison in healthy indian male volunteers. Clin Ther. 2010;32:588-596.
    • (2010) Clin Ther , vol.32 , pp. 588-596
    • Iqbal, M.1    Khuroo, A.2    Batolar, L.S.3    Tandon, M.4    Monif, T.5    Sharma, P.L.6
  • 35
    • 77957352534 scopus 로고    scopus 로고
    • Recent advances in tissue (pro)renin imaging
    • (Elite Ed)
    • Prokai A, Peti-Peterdi J. Recent advances in tissue (pro)renin imaging. Front Biosci (Elite Ed). 2010;2:1227-1233.
    • (2010) Front Biosci , vol.2 , pp. 1227-1233
    • Prokai, A.1    Peti-Peterdi, J.2
  • 36
    • 78149355567 scopus 로고    scopus 로고
    • A high-powered view of the filtration barrier
    • Peti-Peterdi J, Sipos A. A high-powered view of the filtration barrier. J Am Soc Nephrol. 2010;21:1835-1841.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1835-1841
    • Peti-Peterdi, J.1    Sipos, A.2
  • 38
    • 79958121641 scopus 로고    scopus 로고
    • Effect of ace inhibition on glomerular permselectivity and tubular albumin concentration in the renal ablation model
    • Sangalli F, Carrara F, Gaspari F, Corna D, Zoja C, Botti L, et al. Effect of ace inhibition on glomerular permselectivity and tubular albumin concentration in the renal ablation model. Am J Physiol Renal Physiol. 2011;300:F1291-F1300.
    • (2011) Am J Physiol Renal Physiol , vol.300
    • Sangalli, F.1    Carrara, F.2    Gaspari, F.3    Corna, D.4    Zoja, C.5    Botti, L.6
  • 39
    • 84856708866 scopus 로고    scopus 로고
    • Endothelial glycocalyx dysfunction in disease: Albuminuria and altered microvascular permeability
    • Salmon AH, Satchell SC. Endothelial glycocalyx dysfunction in disease: albuminuria and altered microvascular permeability. J Pathol. 2012;226:562-574.
    • (2012) J Pathol , vol.226 , pp. 562-574
    • Salmon, A.H.1    Satchell, S.C.2
  • 40
    • 77950625211 scopus 로고    scopus 로고
    • Maintenance of glomerular filtration barrier integrity requires laminin alpha5
    • Goldberg S, Adair-Kirk TL, Senior RM, Miner JH. Maintenance of glomerular filtration barrier integrity requires laminin alpha5. J Am Soc Nephrol. 2010;21:579-586.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 579-586
    • Goldberg, S.1    Adair-Kirk, T.L.2    Senior, R.M.3    Miner, J.H.4
  • 41
    • 33746520563 scopus 로고    scopus 로고
    • Combined AGE inhibition and ACEi decreases the progression of established diabetic nephropathy in B6 db/db mice
    • DOI 10.1038/sj.ki.5001578, PII 5001578
    • Zheng F, Zeng YJ, Plati AR, Elliot SJ, Berho M, Potier M, et al. Combined age inhibition and acei decreases the progression of established diabetic nephropathy in B6 db/db mice. Kidney Int. 2006;70:507-514. (Pubitemid 44141577)
    • (2006) Kidney International , vol.70 , Issue.3 , pp. 507-514
    • Zheng, F.1    Zeng, Y.-J.2    Plati, A.-R.3    Elliot, S.J.4    Berho, M.5    Potier, M.6    Striker, L.J.7    Striker, G.E.8
  • 42
    • 79952197634 scopus 로고    scopus 로고
    • Treatment of db/db diabetic mice with triptolide: A novel therapy for diabetic nephropathy
    • Gao Q, Shen W, Qin W, Zheng C, Zhang M, Zeng C, et al. Treatment of db/db diabetic mice with triptolide: a novel therapy for diabetic nephropathy. Nephrol Dial Transplant. 2010;25:3539-3547.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 3539-3547
    • Gao, Q.1    Shen, W.2    Qin, W.3    Zheng, C.4    Zhang, M.5    Zeng, C.6
  • 43
    • 33645688929 scopus 로고    scopus 로고
    • Enhanced effect of combined treatment with smp-534 (antifibrotic agent) and losartan in diabetic nephropathy
    • Sugaru E, Nakagawa T, Ono-Kishino M, Nagamine J, Tokunaga T, Kitoh M, et al. Enhanced effect of combined treatment with smp-534 (antifibrotic agent) and losartan in diabetic nephropathy. Am J Nephrol. 2006;26:50-58.
    • (2006) Am J Nephrol , vol.26 , pp. 50-58
    • Sugaru, E.1    Nakagawa, T.2    Ono-Kishino, M.3    Nagamine, J.4    Tokunaga, T.5    Kitoh, M.6
  • 45
    • 77954386779 scopus 로고    scopus 로고
    • Direct renin inhibition improved insulin resistance and adipose tissue dysfunction in type 2 diabetic KK-A(y) mice
    • Iwai M, Kanno H, Tomono Y, Inaba S, Senba I, Furuno M, et al. Direct renin inhibition improved insulin resistance and adipose tissue dysfunction in type 2 diabetic KK-A(y) mice. J Hypertens. 2010;28:1471-1481.
    • (2010) J Hypertens , vol.28 , pp. 1471-1481
    • Iwai, M.1    Kanno, H.2    Tomono, Y.3    Inaba, S.4    Senba, I.5    Furuno, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.