Identification of a novel compound with antiviral activity against influenza A virus depending on PA subunit of viral RNA polymerase

Microbes and Infection

Volumn 14, Issue 9, 2012, Pages 740-747

  Yamada, Kazunori ^a,b   Koyama, Hiroko ^c   Hagiwara, Kyoji ^a   Ueda, Atsushi ^a   Sasaki, Yutaka ^a   Kanesashi, Shin nosuke ^a   Ueno, Ryuki ^c   Nakamura, Hironori K ^d   Kuwata, Kazuo ^d   Shimizu, Kazufumi ^e   Suzuki, Masaaki ^a   Aida, Yoko ^a,b  

^a RIKEN   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d GIFU UNIVERSITY   (Japan)

^e NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Antiviral agents; Influenza a virus; Mini genome assay; Polymerase acidic (PA)

Indexed keywords

ANTIVIRUS AGENT; NUCLEOPROTEIN; POLYMERASE ACIDIC; POLYMERASE BASIC 1; POLYMERASE BASIC 2; RIBONUCLEOPROTEIN; RNA POLYMERASE; THC 19; UNCLASSIFIED DRUG; VIRUS RNA;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; COMPUTATIONAL SCREENING; CONTROLLED STUDY; DRUG IDENTIFICATION; FLOW CYTOMETRY; GENE REPLICATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYDROGEN BOND; INFLUENZA VIRUS A; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; LIFE CYCLE; MOLECULAR LIBRARY; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SCREENING TEST; VIROGENESIS; VIRUS GENOME; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; DOGS; ENZYME INHIBITORS; HUMANS; INFLUENZA A VIRUS; MICROBIAL SENSITIVITY TESTS; RNA REPLICASE; TRANSCRIPTION, GENETIC; VIRAL PROTEINS; VIRUS REPLICATION;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

EID: 84863102609     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2012.02.012     Document Type: Article

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