Splenectomy enhances the anti-fibrotic effect of bone marrow cell infusion and improves liver function in cirrhotic mice and patients

Journal of Gastroenterology

Volumn 47, Issue 3, 2012, Pages 300-312

  Iwamoto, Takuya ^a   Terai, Shuji ^a   Mizunaga, Yuko ^a   Yamamoto, Naoki ^a   Omori, Kaoru ^a   Uchida, Koichi ^a   Yamasaki, Takahiro ^a   Fujii, Yasuhiko ^b   Nishina, Hiroshi ^c   Sakaida, Isao ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b YAMAGUCHI UNIVERSITY HOSPITAL   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Autologous bone marrow cell infusion therapy; CCl4; Liver cirrhosis; Liver regeneration; Splenectomy; Stem cell therapy

Indexed keywords

ALBUMIN; CARBON TETRACHLORIDE; CYCLINE; GELATINASE B; GREEN FLUORESCENT PROTEIN;

AGED; ALBUMIN BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; BONE MARROW CELL; CELL MIGRATION; CELL REPOPULATION; CONTROLLED STUDY; ESOPHAGUS VARICES; FEMALE; HUMAN; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER FUNCTION; LIVER REGENERATION; MICROENVIRONMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SPLENECTOMY; THROMBOCYTOPENIA; TREATMENT OUTCOME;

AGED; ANIMALS; BONE MARROW TRANSPLANTATION; COMBINED MODALITY THERAPY; FEMALE; HUMANS; LIVER CIRRHOSIS; LIVER CIRRHOSIS, EXPERIMENTAL; LIVER FUNCTION TESTS; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MIDDLE AGED; SERUM ALBUMIN; SPLENECTOMY;

EID: 84863089197     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-011-0486-7     Document Type: Article

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