Role of the spleen in liver fibrosis in rats may be mediated by transforming growth factor β-1

Journal of Gastroenterology and Hepatology (Australia)

Volumn 17, Issue 1, 2002, Pages 59-65

  Akahoshi, Tomohiko ^a   Hashizume, Makoto ^b   Tanoue, Kazuo ^a   Shimabukuro, Rinshyun ^a   Gotoh, Norikazu ^b   Tomikawa, Morimasa ^a   Sugimachi, Keizo ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Hepatic regeneration; Hypersplenism; Liver fibrosis; Transforming growth factor 1

Indexed keywords

MONOCLONAL ANTIBODY; THIOACETAMIDE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; LABELING INDEX; LIVER CELL; LIVER CIRRHOSIS; MACROPHAGE; MALE; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; SPLENECTOMY;

EID: 0036222947     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1746.2002.02667.x     Document Type: Article

References (32)

1. Role of spleen in regeneration of liver
2. Influence of humoral and splenic factors in hepatic regeneration
3. Milz/leberziehungen model der experimentally tioacetamide-cirrhose der rantenleber. Die milz edittores: Karl Lennert
4. An experimental study of a splenic inhibitory factor influencing hepatic regeneration
5. The role of the spleen, platelets, and plasma hepatocyte growth factor activity on hepatic regeneration in rats
6. The mechanism for splenic promoting effect on liver cirrhosis
7. The result of splenectomy in Banti's syndrome
8. The late phase of congestive splenomegaly (Banti's syndrome) with hematmesis but without cirrhosis of the liver. Further observations on the etiology of Bant's syndrome and effect on prognosis of certain variations in the portal venous pattern
9. Role of the spleen on the pathogenesis of schistosomal periportal fibrosis of the liver: An experimental approach
10. Transcatheter partial splenic arterial embolization in patients with hypersplenism. A clinical evaluation as supporting therapy for hepatocellular carcinoma and liver cirrhosis
11. Long term follow-up for patients with liver cirrhosis after partial splenicc embolization
12. Portal venous pressure following splenectomy in patients with portal hypertension of differing etiology
13. Control of bleeding esophageal varices by transabdominal esophageal transection, gastric devascularization, and splenectomy
14. New class of transforming growth factors potentiated by epidermal growth factor: Isolation from non-neoplastic tissues
15. Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms Treatmentstrategies
16. Perisinusoidal stellate cells of the liver: Important roles in retinol metabolism and fibrosis
17. Transforming growth factor beta in tissue fibrosis
18. Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions
19. Enzyme leakage due to change of membrane permeability of primary cultured rat hepatocytes treated with various hepatotoxins and its prevention by glycyrhizin
20. Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor-β1
21. Hepatocyte growth factor gene therapy of liver cirrhosis in rats
22. Preparation of isolated rat liver cells
23. Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroforn extraction
24. Quantitation of mRNA species by RT-PCR on total mRNA population
25. Students on the metabolism of thioacetamide-S35 in the intact rat
26. Transposition of the spleen in rats with portal hypertension
27. Carbon tetrachrolide cirrhosis in relation to liver regeneration
28. Expression of cytokine genes during liver regeneration after partial hepatectomy in rats
29. Role of endotoxin-responsive macrophages hepatic injuary
30. Siginificance of endotoxaemia in experimental galactosamine hepatitis in the rat
31. Involvement of tumor necrosis factor-α in development of hepatic injuary in galactosamine-sensitized mice