Genetic polymorphisms in key DNA repair genes and risk of head and neck cancer in a Chinese population

Experimental and Therapeutic Medicine

Volumn 3, Issue 4, 2012, Pages 719-724

  Yuan, Hua ^a   Li, Huizhang ^a   Ma, Hongxia ^a   Niu, Yuming ^a   Wu, Yunong ^a   Zhang, Shangyue ^b   Hu, Zhibin ^a   Shen, Hongbing ^a   Chen, Ning ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b THE AFFILIATED HUAIAN NO 1 PEOPLE S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

DNA repair; Head and neck cancer; Polymorphisms; Risk

Indexed keywords

ADPRT PROTEIN; APOLIPOPROTEIN E; APOLIPOPROTEIN E1; TUMOR PROTEIN; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP D PROTEIN; XPG PROTEIN; XRCC1 PROTEIN;

ADULT; ARTICLE; CANCER PATIENT; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; DNA REPAIR; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; HEAD AND NECK CANCER; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING HABIT;

EID: 84863059651     PISSN: 17920981     EISSN: 17921015     Source Type: Journal    
DOI: 10.3892/etm.2012.476     Document Type: Article

References (63)

1. Marcu LG and Yeoh E: A review of risk factors and genetic alterations in head and neck carcinogenesis and implications for current and future approaches to treatment. J Cancer Res Clin Oncol 135: 1303-1314, 2009.
2. Jemal A, Siegel R, Xu J and Ward E: Cancer statistics, 2010. CA Cancer J Clin 60: 277-300, 2010.
3. Choi SY and Kahyo H: Effect of cigarette smoking and alcohol consumption in the aetiology of cancer of the oral cavity, pharynx and larynx. Int J Epidemiol 20: 878-885, 1991.
4. Phillips DH: Smoking-related DNA and protein adducts in human tissues. Carcinogenesis 23: 1979-2004, 2002.
5. Stokes MP and Comb MJ: A wide-ranging cellular response to UV damage of DNA. Cell Cycle 7: 2097-2099, 2008.
6. Wei Q, Cheng L, Hong WK and Spitz MR: Reduced DNA repair capacity in lung cancer patients. Cancer Res 56: 4103-4107, 1996.
7. Cheng L, Eicher SA, Guo Z, Hong WK, Spitz MR and Wei Q: Reduced DNA repair capacity in head and neck cancer patients. Cancer Epidemiol Biomarkers Prev 7: 465-468, 1998.
8. Wang LE, Hu Z, Sturgis EM, et al: Reduced DNA repair capacity for removing tobacco carcinogen-induced DNA adducts contributes to risk of head and neck cancer but not tumor characteristics. Clin Cancer Res 16: 764-774, 2010.
9. Wood RD: DNA damage recognition during nucleotide excision repair in mammalian cells. Biochimie 81: 39-44, 1999.
10. Hung RJ, Hall J, Brennan P and Boffetta P: Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review. Am J Epidemiol 162: 925-942, 2005.
11. Tell G, Damante G, Caldwell D and Kelley MR: The intracellular localization of APE1/Ref-1: more than a passive phenomenon? Antioxid Redox Signal 7: 367-384, 2005.
12. Caldecott KW: XRCC1 and DNA strand break repair. DNA Repair (Amst) 2: 955-969, 2003.
13. Masson M, Niedergang C, Schreiber V, Muller S, Menissier de Murcia J and de Murcia G: XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage. Mol Cell Biol 18: 3563-3571, 1998.
14. Spitz MR, Wu X, Wang Y, et al: Modulation of nucleotide excision repair capacity by XPD polymorphisms in lung cancer patients. Cancer Res 61: 1354-1357, 2001.
15. Qiao Y, Spitz MR, Guo Z, et al: Rapid assessment of repair of ultraviolet DNA damage with a modified host-cell reactivation assay using a luciferase reporter gene and correlation with polymorphisms of DNA repair genes in normal human lymphocytes. Mutat Res 509: 165-174, 2002.
16. Shen J, Desai M, Agrawal M, et al: Polymorphisms in nucleotide excision repair genes and DNA repair capacity phenotype in sisters discordant for breast cancer. Cancer Epidemiol Biomarkers Prev 15: 1614-1619, 2006.
17. Flores-Obando RE, Gollin SM and Ragin CC: Polymorphisms in DNA damage response genes and head and neck cancer risk. Biomarkers 15: 379-399, 2010.
18. Cui Y, Morgenstern H, Greenland S, et al: Polymorphism of Xeroderma pigmentosum group G and the risk of lung cancer and squamous cell carcinomas of the oropharynx, larynx and esophagus. Int J Cancer 118: 714-720, 2006.
19. Gugatschka M, Dehchamani D, Wascher TC, Friedrich G and Renner W: DNA repair gene ERCC2 polymorphisms and risk of squamous cell carcinoma of the head and neck. Exp Mol Pathol 91: 331-334, 2010.
20. Hiyama T, Yoshihara M, Tanaka S and Chayama K: Genetic polymorphisms and head and neck cancer risk (Review). Int J Oncol 32: 945-973, 2008.
21. Wang Y, Yang H, Li H, et al: Association between X-ray repair cross complementing group 1 codon 399 and 194 polymorphisms and lung cancer risk: a meta-analysis. Cancer Lett 285: 134-140, 2009.
22. Yin M, Tan D and Wei Q: Genetic variants of the XRCC1 gene and susceptibility to esophageal cancer: a meta-analysis. Int J Clin Exp Med 2: 26-35, 2009.
23. Wang F, Chang D, Hu FL, et al: DNA repair gene XPD polymorphisms and cancer risk: a meta-analysis based on 56 case-control studies. Cancer Epidemiol Biomarkers Prev 17: 507-517, 2008.
24. Hu Z, Wei Q, Wang X and Shen H: DNA repair gene XPD polymorphism and lung cancer risk: a meta-analysis. Lung Cancer 46: 1-10, 2004.
25. Li C, Hu Z, Lu J, et al: Genetic polymorphisms in DNA base-excision repair genes ADPRT, XRCC1, and APE1 and the risk of squamous cell carcinoma of the head and neck. Cancer 110: 867-875, 2007.
26. Vineis P, Manuguerra M, Kavvoura FK, et al: A field synopsis on low-penetrance variants in DNA repair genes and cancer susceptibility. J Natl Cancer Inst 101: 24-36, 2009.
27. Shen MR, Jones IM and Mohrenweiser H: Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans. Cancer Res 58: 604-608, 1998.
28. Xing DY, Qi J, Tan W, et al: Association of genetic polymorphisms in the DNA repair gene XPD with risk of lung and esophageal cancer in a Chinese population in Beijing. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 20: 35-38, 2003. (In Chinese).
29. An J, Liu Z, Hu Z, et al: Potentially functional single nucleotide polymorphisms in the core nucleotide excision repair genes and risk of squamous cell carcinoma of the head and neck. Cancer Epidemiol Biomarkers Prev 16: 1633-1638, 2007.
30. Bau DT, Tsai MH, Huang CY, et al: Relationship between polymorphisms of nucleotide excision repair genes and oral cancer risk in Taiwan: evidence for modification of smoking habit. Chin J Physiol 50: 294-300, 2007.
31. Huang WY, Olshan AF, Schwartz SM, et al: Selected genetic polymorphisms in MGMT, XRCC1, XPD, and XRCC3 and risk of head and neck cancer: a pooled analysis. Cancer Epidemiol Biomarkers Prev 14: 1747-1753, 2005.
32. Kietthubthew S, Sriplung H, Au WW and Ishida T: Polymorphism in DNA repair genes and oral squamous cell carcinoma in Thailand. Int J Hyg Environ Health 209: 21-29, 2006.
33. Majumder M, Sikdar N, Ghosh S and Roy B: Polymorphisms at XPD and XRCC1 DNA repair loci and increased risk of oral leukoplakia and cancer among NAT2 slow acetylators. Int J Cancer 120: 2148-2156, 2007.
34. Ramachandran S, Ramadas K, Hariharan R, Rejnish Kumar R and Radhakrishna Pillai M: Single nucleotide polymorphisms of DNA repair genes XRCC1 and XPD and its molecular mapping in Indian oral cancer. Oral Oncol 42: 350-362, 2006.
35. Sturgis EM, Zheng R, Li L, et al: XPD/ERCC2 polymorphisms and risk of head and neck cancer: a case-control analysis. Carcinogenesis 21: 2219-2223, 2000.
36. Abbasi R, Ramroth H, Becher H, Dietz A, Schmezer P and Popanda O: Laryngeal cancer risk associated with smoking and alcohol consumption is modified by genetic polymorphisms in ERCC5, ERCC6 and RAD23B but not by polymorphisms in five other nucleotide excision repair genes. Int J Cancer 125: 1431-1439, 2009.
37. Matullo G, Dunning AM, Guarrera S, et al: DNA repair polymorphisms and cancer risk in non-smokers in a cohort study. Carcinogenesis 27: 997-1007, 2006.
38. Rydzanicz M, Wierzbicka M, Gajecka M, Szyfter W and Szyfter K: The impact of genetic factors on the incidence of multiple primary tumors (MPT) of the head and neck. Cancer Lett 224: 263-278, 2005.
39. Gajecka M, Rydzanicz M, Jaskula-Sztul R, Wierzbicka M, Szyfter W and Szyfter K: Reduced DNA repair capacity in laryngeal cancer subjects. A comparison of phenotypic and genotypic results. Adv Otorhinolaryngol 62: 25-37, 2005.
40. Wakasugi M, Reardon JT and Sancar A: The non-catalytic function of XPG protein during dual incision in human nucleotide excision repair. J Biol Chem 272: 16030-16034, 1997.
41. O'Donovan A, Davies AA, Moggs JG, West SC and Wood RD: XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair. Nature 371: 432-435, 1994.
42. Bessho T: Nucleotide excision repair 3' endonuclease XPG stimulates the activity of base excision repair enzyme thymine glycol DNA glycosylase. Nucleic Acids Res 27: 979-983, 1999.
43. Klungland A, Hoss M, Gunz D, et al: Base excision repair of oxidative DNA damage activated by XPG protein. Mol Cell 3: 33-42, 1999.
44. Jorgensen TJ, Visvanathan K, Ruczinski I, Thuita L, Hoffman S and Helzlsouer KJ: Breast cancer risk is not associated with polymorphic forms of xeroderma pigmentosum genes in a cohort of women from Washington County, Maryland. Breast Cancer Res Treat 101: 65-71, 2007.
45. Kiyohara C and Yoshimasu K: Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: a meta-analysis. Int J Med Sci 4: 59-71, 2007.
46. Hussain SK, Mu LN, Cai L, et al: Genetic variation in immune regulation and DNA repair pathways and stomach cancer in China. Cancer Epidemiol Biomarkers Prev 18: 2304-2309, 2009.
47. Garcia-Closas M, Malats N, Real FX, et al: Genetic variation in the nucleotide excision repair pathway and bladder cancer risk. Cancer Epidemiol Biomarkers Prev 15: 536-542, 2006.
48. Mort R, Mo L, McEwan C and Melton DW: Lack of involvement of nucleotide excision repair gene polymorphisms in colorectal cancer. Br J Cancer 89: 333-337, 2003.
49. Wen SX, Tang PZ, Zhang XM, et al: Association between genetic polymorphism in xeroderma pigmentosum G gene and risks of laryngeal and hypopharyngeal carcinomas. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 28: 703-706, 2006 (In Chinese).
50. Manuguerra M, Matullo G, Veglia F, et al: Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions. Carcinogenesis 28: 414-422, 2007.
51. Izumi T, Wiederhold LR, Roy G, et al: Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage. Toxicology 193: 43-65, 2003.
52. Dianov GL, Sleeth KM, Dianova II and Allinson SL: Repair of abasic sites in DNA. Mutat Res 531: 157-163, 2003.
53. Hu JJ, Smith TR, Miller MS, Mohrenweiser HW, Golden A and Case LD: Amino acid substitution variants of APE1 and XRCC1 genes associated with ionizing radiation sensitivity. Carcinogenesis 22: 917-922, 2001.
54. Jelonek K, Gdowicz-Klosok A, Pietrowska M, et al: Association between single-nucleotide polymorphisms of selected genes involved in the response to DNA damage and risk of colon, head and neck, and breast cancers in a Polish population. J Appl Genet 51: 343-352, 2010.
55. Caldecott KW, Tucker JD, Stanker LH and Thompson LH: Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells. Nucleic Acids Res 23: 4836-4843, 1995.
56. Lunn RM, Langlois RG, Hsieh LL, Thompson CL and Bell DA: XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency. Cancer Res 59: 2557-2561, 1999.
57. Lei YC, Hwang SJ, Chang CC, et al: Effects on sister chromatid exchange frequency of polymorphisms in DNA repair gene XRCC1 in smokers. Mutat Res 519: 93-101, 2002.
58. Wei B, Zhou Y, Xu Z, et al: XRCC1 Arg399Gln and Arg194Trp polymorphisms in prostate cancer risk: a meta-analysis. Prostate Cancer Prostatic Dis 14: 225-231, 2010.
59. Saadat M: Haplotype analysis of XRCC1 (at codons 194 and 399) and susceptibility to breast cancer, a meta-analysis of the literatures. Breast Cancer Res Treat 124: 785-791, 2010.
60. Zheng H, Wang Z and Shi X: XRCC1 polymorphisms and lung cancer risk in Chinese populations: a meta-analysis. Lung Cancer 65: 268-273, 2009.
61. Hu Z, Ma H, Chen F, Wei Q and Shen H: XRCC1 polymorphisms and cancer risk: a meta-analysis of 38 case-control studies. Cancer Epidemiol Biomarkers Prev 14: 1810-1818, 2005.
62. Kumari SR, Mendoza-Alvarez H and Alvarez-Gonzalez R: Functional interactions of p53 with poly(ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: covalent poly(ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the M(r) 85,000 proteolytic fragment. Cancer Res 58: 5075-5078, 1998.
63. Lockett KL, Hall MC, Xu J, et al: The ADPRT V762A genetic variant contributes to prostate cancer susceptibility and deficient enzyme function. Cancer Res 64: 6344-6348, 2004.