Pregnancy augments hepatic glucose storage in response to a mixed meal

British Journal of Nutrition

Volumn 107, Issue 4, 2012, Pages 493-503

  Moore, Mary Courtney ^a   Smith, Marta S ^a   Connolly, Cynthia C ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Glucose; Metabolism; Pregnancy

Indexed keywords

CARBON 14; GLUCOSE; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE DIET; CHEMICAL LABELING; CONTROLLED STUDY; EXPERIMENTAL DOG; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE OXIDATION; GLUCOSE TRANSPORT; GLYCOGEN SYNTHESIS; HINDLIMB; HUMAN; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INTESTINE MUCOSA; LIVER METABOLISM; MATERNAL NUTRITION; MEAL; MOTHER FETUS RELATIONSHIP; NONHUMAN; NUTRIENT SUPPLY; NUTRITIONAL REQUIREMENT; POSTPRANDIAL STATE; PREGNANCY OUTCOME; SKELETAL MUSCLE; THIRD TRIMESTER PREGNANCY;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD GLUCOSE; DOGS; FEMALE; GLUCOSE; GLYCOGEN; GLYCOLYSIS; HINDLIMB; HYPERGLYCEMIA; HYPOGLYCEMIA; INSULIN; INTESTINAL ABSORPTION; KINETICS; LIVER; LIVER GLYCOGEN; MODELS, ANIMAL; MUSCLE, SKELETAL; OXIDATION-REDUCTION; POSTPRANDIAL PERIOD; PREGNANCY;

ANIMALIA; CANIS FAMILIARIS;

EID: 84863045452     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114511003187     Document Type: Article

References (50)

1. Catalano PM, Tyzbir ED, Wolfe RR, et al. (1992) Longitudinal changes in basal hepatic glucose production and suppression during insulin infusion in normal pregnant women. Am J Obstet Gynecol 167, 913-919.
2. Girard J, Burnol AF, Leturque A, et al. (1987) Glucose homoeostasis in pregnancy and lactation. Biochem Soc Trans 15, 1028-1030. (Pubitemid 18036265)
3. Gilbert M, Pere MC, Baudelin A, et al. (1991) Role of free fatty acids in hepatic insulin resistance during late pregnancy in conscious rabbits. Am J Physiol 260, E938-E945.
4. Butte NF (2000) Carbohydrate and lipid metabolism in pregnancy: Normal compared with gestational diabetes mellitus. Am J Clin Nutr 71, 1256S-1261S. (Pubitemid 30230526)
5. Connolly CC, Papa T, Smith MS, et al. (2007) Hepatic and muscle insulin action during late pregnancy in the dog. Am J Physiol Regul Integr Comp Physiol 292, R447-R452. (Pubitemid 46089860)
6. Lain KY & Catalano PM (2007) Metabolic changes in pregnancy. Clin Obstet Gynecol 50, 938-948. (Pubitemid 350059291)
7. Maki KC, Rains TM, Dicklin MR, et al. (2010) Repeatability of indices of insulin sensitivity and secretion from standard liquid meal tests in subjects with type 2 diabetes mellitus or normal or impaired fasting glucose. Diabetes Technol Ther 12, 895-900.
8. Owens DR, Wragg KG, Biggs PI, et al. (1981) The reproducibility of serial meal and oral glucose tolerance tests in normal subjects. Diabete Metab 7, 25-33. (Pubitemid 11089589)
9. Wolever TM, Chiasson JL, Csima A, et al. (1998) Variation of postprandial plasma glucose, palatability, and symptoms associated with a standardized mixed test meal versus 75 g oral glucose. Diabetes Care 21, 336-340. (Pubitemid 28101065)
10. Moore MC, Pagliassotti MJ, Swift LL, et al. (1994) Disposition of a mixed meal by the conscious dog. Am J Physiol 266, E666-E675.
11. Wasserman DH, Lacy DB, Bracy D, et al. (1992) Metabolic regulation in peripheral tissues and transition to increased gluconeogenic mode during prolonged exercise. Am J Physiol 263, E345-E354.
12. Connolly CC, Holste LC, Aglione LN, et al. (2000) Alterations in basal glucose metabolism during late pregnancy in the conscious dog. Am J Physiol Endocrinol Metab 279, E1166-E1177.
13. Pagliassotti MJ, Holste LC, Moore MC, et al. (1996) Comparison of the time courses of insulin and the portal signal on hepatic glucose and glycogen metabolism in the conscious dog. J Clin Invest 97, 81-91. (Pubitemid 26021697)
14. Shiota M, Golden S & Katz J.1984) Lactate metabolism in the perfused rat hindlimb. Biochem J 222, 281-292. (Pubitemid 14004907)
15. Keppler D & Decker K (1974) Glycogen: Determination with amyloglucosidase. In Methods of Enzymatic Analysis, pp. 1127-1131 [HU Bergmeyer, editor]. New York: Verlag Chemic Weinheim, Academic Press.
16. Moore MC, Menon R, Coate KC, et al. (2011) Diet-induced impaired glucose tolerance and gestational diabetes in the dog. J Appl Physiol 110, 458-467.
17. Liu CY, Chen LB, Liu PY, et al. (2002) Effects of progesterone on gastric emptying and intestinal transit in male rats. World J Gastroenterol 8, 338-341.
18. Jones KL, Berry M, Kong MF, et al. (1999) Hyperglycemia attenuates the gastrokinetic effect of erythromycin and affects the perception of postprandial hunger in normal subjects. Diabetes Care 22, 339-344. (Pubitemid 29056932)
19. Kuo P, Gentilcore D, Nair N, et al. (2009) The nitric oxide synthase inhibitor, n g-nitro-L-arginine-methyl-ester, attenuates the delay in gastric emptying induced by hyperglycaemia in healthy humans. Neurogastroenterol Motil 21, 1175-e103.
20. Cherrington AD (1999) Banting lecture 1997. Control of glucose uptake and release by the liver in vivo. Diabetes 48, 1198-1214. (Pubitemid 29226371)
21. Pere MC, Baudelin A, Briggs K, et al. (1992) Hepatic metabolism during fasting-refeeding transition in conscious pregnant rabbits. Am J Physiol 262, E899-E905.
22. Hauguel S, Gilbert M & Girard J.1987) Pregnancy-induced insulin resistance in liver and skeletal muscles of the conscious rabbit. Am J Physiol 252, E165-E169.
23. Catalano PM, Nizielski SE, Shao J, et al. (2002) Downregulated IRS-1 and PPARgamma in obese women with gestational diabetes: Relationship to FFA during pregnancy. Am J Physiol Endocrinol Metab 282, E522-E533. (Pubitemid 34654766)
24. Metzger BE, Ravnikar V, Vileisis RA, et al. (1982) "Accelerated starvation" and the skipped breakfast in late normal pregnancy. Lancet 1, 588-592. (Pubitemid 12171822)
25. Sivan E, Homko CJ, Chen X, et al. (1999) Effect of insulin on fat metabolism during and after normal pregnancy. Diabetes 48, 834-838. (Pubitemid 29153084)
26. Connolly CC, Aglione LN, Smith MS, et al. (2004) Pregnancy impairs the counterregulatory response to insulin-induced hypoglycemia in the dog. Am J Physiol Endocrinol Metab 287, E480-E488. (Pubitemid 39095882)
27. Sivan E, Homko CJ, Whittaker PG, et al. (1998) Free fatty acids and insulin resistance during pregnancy. J Clin Endocrinol Metab 83, 2338-2342. (Pubitemid 28503024)
28. Cherrington AD, Edgerton D & Sindelar DK (1998) The direct and indirect effects of insulin on hepatic glucose production in vivo. Diabetologia 41, 987-996. (Pubitemid 28394402)
29. Moore MC, Smith MS, Lacy DB, et al. (2008) The liver's response to hyperglycemia is delayed in late pregnancy. Diabetes 57, A512.
30. Blanco PG, Tórtora M, Rodríguez R, et al. (2010) Ultrasonographic assessment of maternal cardiac function and peripheral circulation during normal gestation in dogs. Vet J.epublication ahead of print version 11 october 2010).
31. Connolly CC, Aglione LN, Smith MS, et al. (2004) Insulin action during late pregnancy in the conscious dog. Am J Physiol Endocrinol Metab 286, E909-E915. (Pubitemid 38668812)
32. Canniff KM, Smith MS, Lacy DB, et al. (2006) Glucagon secretion and autonomic signaling during hypoglycemia in late pregnancy. Am J Physiol Regul Integr Comp Physiol 291, R788-R795. (Pubitemid 44352363)
33. Nautrup CP (1998) Doppler ultrasonography of canine maternal and fetal arteries during normal gestation. J Reprod Fertil 112, 301-314. (Pubitemid 28243096)
34. Munnell EW & Taylor HC (1947) Liver blood flow in pregnancy - hepatic vein catheterization. J Clin Invest 26, 952-956.
35. Clapp JF 3rd, Stepanchak W, Tomaselli J, et al. (2000) Portal vein blood flow - effects of pregnancy, gravity, and exercise. Am J Obstet Gynecol 183, 167-172. (Pubitemid 30626045)
36. Nakai A, Sekiya I, Oya A, et al. (2002) Assessment of the hepatic arterial and portal venous blood flows during pregnancy with Doppler ultrasonography. Arch Gynecol Obstet 266, 25-29. (Pubitemid 36055953)
37. Bozgeyik Z, Ozdemir H, Kocakoc E, et al. (2009) Hepatic and portal venous Doppler waveforms and flow velocities in normal pregnancy. Med Sci Monit 15, CR624-CR627.
38. Herrera E, Knopp RH & Freinkel N (1969) Carbohydrate metabolism in pregnancy. VI. Plasma fuels, insulin, liver composition, gluconeogenesis, and nitrogen metabolism during late gestation in the fed and fasted rat. J Clin Invest 48, 2260-2272.
39. Hendrick GK, Frizzell RT, Williams PE, et al. (1990) Effect of hyperglucagonemia on hepatic glycogenolysis and gluconeogenesis after a prolonged fast. Am J Physiol 258, E841-E849. (Pubitemid 20179446)
40. Galassetti P, Hamilton KS, Gibbons FK, et al. (1999) Effect of fast duration on disposition of an intraduodenal glucose load in the conscious dog. Am J Physiol 276, E543-E552. (Pubitemid 29157411)
41. Concannon PW, McCann JP & Temple M (1989) Biology and endocrinology of ovulation, pregnancy and parturition in the dog. Journal Reprod Fert Suppl 39, 3-25.
42. Carrington LJ & Bailey CJ (1985) Effects of natural and synthetic estrogens and progestins on glycogen deposition in female mice. Horm Res 21, 199-203. (Pubitemid 15090296)
43. Mohla S & PrasadMR (1968) Inhibition of estrogen induced glycogen synthesis in the rat by clomiphene. Steroids 11, 571-583.
44. Kalkhoff RK (1982) Metabolic effects of progesterone. Am J Obstet Gynecol 142, 735-738. (Pubitemid 12135894)
45. Rossi G, Lapaczewski P, Diamond MP, et al. (1993) Inhibitory effect of pregnancy on counterregulatory hormone responses to hypoglycemia in awake rat. Diabetes 42, 1440-1445. (Pubitemid 23277200)
46. Rosenn BM, Miodovnik M, Khoury JC, et al. (1996) Counterregulatory hormonal responses to hypoglycemia during pregnancy. Obstet Gynecol 87, 568-574. (Pubitemid 26102743)
47. Moore MC, Pagliassotti MJ, Wasserman DH, et al. (1993) Hepatic denervation alters the transition from the fed to the food-deprived state in conscious dogs. J Nutr 23, 1739-1746. (Pubitemid 23317242)
48. Defronzo RA (2009) Banting lecture. From the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus. Diabetes 58, 773-795.
49. Abdul-Ghani MA, Matsuda M, Balas B, et al. (2007) Muscle and liver insulin resistance indexes derived from the oral glucose tolerance test. Diabetes Care 30, 89-94. (Pubitemid 46052504)
50. Abdul-Ghani MA, Williams K, DeFronzo RA, et al. (2007) What is the best predictor of future type 2 diabetes? Diabetes Care 30, 1544-1548. (Pubitemid 46871168)