Exposing a hidden functional site of C-reactive protein by site-directed mutagenesis

Journal of Biological Chemistry

Volumn 287, Issue 5, 2012, Pages 3550-3558

  Singh, Sanjay K ^a   Thirumalai, Avinash ^a   Hammond, David J ^a   Pangburn, Michael K ^b   Mishra, Vinod K ^c   Johnson, David A ^a   Rusiñol, Antonio E ^a   Agrawal, Alok ^a  

^a East Tennessee State University   (United States)

^b UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; DISEASES; MUTAGENESIS; PHYSIOLOGY;

ACIDIC PH; ANIMAL MODEL; BINDING ACTIVITIES; BINDING-SITES; C-REACTIVE PROTEINS; FUNCTIONAL SITES; PHYSIOLOGICAL PH; PROTEIN MUTANTS; SITE DIRECTED MUTAGENESIS; WILD TYPES;

PROTEINS;

C REACTIVE PROTEIN; GLUTAMINE; MUTANT PROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN;

ACIDITY; AMINO ACID SUBSTITUTION; ARTICLE; ATHEROSCLEROSIS; BINDING AFFINITY; BINDING SITE; CIRCULAR DICHROISM; CONTROLLED STUDY; GEL FILTRATION; HYDROPHOBICITY; INFLAMMATION; MOLECULAR INTERACTION; MOLECULAR MODEL; PH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; WILD TYPE;

ANIMALIA;

EID: 84863044357     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.310011     Document Type: Article

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