메뉴 건너뛰기




Volumn 7, Issue 2, 2012, Pages

MicroRNA-520b inhibits growth of hepatoma cells by targeting MEKK2 and cyclin D1

Author keywords

[No Author keywords available]

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 5 ETHYNYL 2 DEOXYURIDINE; CYCLIN D1; DEOXYURIDINE DERIVATIVE; MICRORNA; MICRORNA 520B; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 2; RETINOBLASTOMA PROTEIN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; MAP3K2 PROTEIN, HUMAN; MIRN520 MICRORNA, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE;

EID: 84863040849     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031450     Document Type: Article
Times cited : (68)

References (28)
  • 1
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 2
    • 40949087185 scopus 로고    scopus 로고
    • Identification of metastasis-related microRNAs in hepatocellular carcinoma
    • Budhu A, Jia HL, Forgues M, Liu CG, Goldstein D, et al. (2008) Identification of metastasis-related microRNAs in hepatocellular carcinoma. Hepatology 47: 897-907.
    • (2008) Hepatology , vol.47 , pp. 897-907
    • Budhu, A.1    Jia, H.L.2    Forgues, M.3    Liu, C.G.4    Goldstein, D.5
  • 3
    • 77956305756 scopus 로고    scopus 로고
    • MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2
    • Dong Q, Meng P, Wang T, Qin W, Wang F, et al. (2010) MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2. PLoS One 5: e10147.
    • (2010) PLoS One , vol.5
    • Dong, Q.1    Meng, P.2    Wang, T.3    Qin, W.4    Wang, F.5
  • 4
    • 79952795512 scopus 로고    scopus 로고
    • MicroRNAs 15a/16-1 function as tumor suppressor genes in multiple myeloma
    • Gatt ME, Zhao JJ, Ebert MS, Zhang Y, Chu Z, et al. (2010) MicroRNAs 15a/16-1 function as tumor suppressor genes in multiple myeloma. Blood 117: 7188.
    • (2010) Blood , vol.117 , pp. 7188
    • Gatt, M.E.1    Zhao, J.J.2    Ebert, M.S.3    Zhang, Y.4    Chu, Z.5
  • 5
    • 66449136951 scopus 로고    scopus 로고
    • Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
    • Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, et al. (2009) Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137: 1005-1017.
    • (2009) Cell , vol.137 , pp. 1005-1017
    • Kota, J.1    Chivukula, R.R.2    O'Donnell, K.A.3    Wentzel, E.A.4    Montgomery, C.L.5
  • 6
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, et al. (2007) MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133: 647-658.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5
  • 7
    • 70949104622 scopus 로고    scopus 로고
    • MiR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation
    • Garofalo M, Di Leva G, Romano G, Nuovo G, Suh SS, et al. (2009) miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation. Cancer Cell 16: 498-509.
    • (2009) Cancer Cell , vol.16 , pp. 498-509
    • Garofalo, M.1    Di Leva, G.2    Romano, G.3    Nuovo, G.4    Suh, S.S.5
  • 8
    • 70450285075 scopus 로고    scopus 로고
    • MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib
    • Bai S, Nasser MW, Wang B, Hsu SH, Datta J, et al. (2009) MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. J Biol Chem 284: 32015-32027.
    • (2009) J Biol Chem , vol.284 , pp. 32015-32027
    • Bai, S.1    Nasser, M.W.2    Wang, B.3    Hsu, S.H.4    Datta, J.5
  • 9
    • 66149114383 scopus 로고    scopus 로고
    • MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma
    • Tsai WC, Hsu PW, Lai TC, Chau GY, Lin CW, et al. (2009) MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma. Hepatology 49: 1571-1582.
    • (2009) Hepatology , vol.49 , pp. 1571-1582
    • Tsai, W.C.1    Hsu, P.W.2    Lai, T.C.3    Chau, G.Y.4    Lin, C.W.5
  • 10
    • 77955488537 scopus 로고    scopus 로고
    • MiRNA-520b and miR-520e sensitize breast cancer cells to complement attack via directly targeting 3′UTR of CD46
    • Cui W, Zhang Y, Hu N, Shan C, Zhang S, et al. (2010) miRNA-520b and miR-520e sensitize breast cancer cells to complement attack via directly targeting 3′UTR of CD46. Cancer Biol Ther 10: 232-241.
    • (2010) Cancer Biol Ther , vol.10 , pp. 232-241
    • Cui, W.1    Zhang, Y.2    Hu, N.3    Shan, C.4    Zhang, S.5
  • 11
    • 79953875382 scopus 로고    scopus 로고
    • MiR-520b regulates migration of breast cancer cells through targeting hepatitis B X-interacting protein and interleukin-8
    • Hu N, Zhang J, Cui W, Kong G, Zhang S, et al. (2011) miR-520b regulates migration of breast cancer cells through targeting hepatitis B X-interacting protein and interleukin-8. J Biol Chem 286: 13714-13722.
    • (2011) J Biol Chem , vol.286 , pp. 13714-13722
    • Hu, N.1    Zhang, J.2    Cui, W.3    Kong, G.4    Zhang, S.5
  • 12
    • 79551663938 scopus 로고    scopus 로고
    • Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer
    • Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, et al. (2011) Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer. Proc Natl Acad Sci U S A 108: 780-785.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 780-785
    • Hayakawa, Y.1    Hirata, Y.2    Nakagawa, H.3    Sakamoto, K.4    Hikiba, Y.5
  • 13
    • 0035805552 scopus 로고    scopus 로고
    • MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression
    • Su B, Cheng J, Yang J, Guo Z, (2001) MEKK2 is required for T-cell receptor signals in JNK activation and interleukin-2 gene expression. J Biol Chem 276: 14784-14790.
    • (2001) J Biol Chem , vol.276 , pp. 14784-14790
    • Su, B.1    Cheng, J.2    Yang, J.3    Guo, Z.4
  • 14
    • 0035836668 scopus 로고    scopus 로고
    • Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells
    • Chayama K, Papst PJ, Garrington TP, Pratt JC, Ishizuka T, et al. (2001) Role of MEKK2-MEK5 in the regulation of TNF-alpha gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells. Proc Natl Acad Sci U S A 98: 4599-4604.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4599-4604
    • Chayama, K.1    Papst, P.J.2    Garrington, T.P.3    Pratt, J.C.4    Ishizuka, T.5
  • 15
    • 0033213597 scopus 로고    scopus 로고
    • Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor
    • Schaefer BC, Ware MF, Marrack P, Fanger GR, Kappler JW, et al. (1999) Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor. Immunity 11: 411-421.
    • (1999) Immunity , vol.11 , pp. 411-421
    • Schaefer, B.C.1    Ware, M.F.2    Marrack, P.3    Fanger, G.R.4    Kappler, J.W.5
  • 16
    • 0037378478 scopus 로고    scopus 로고
    • MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src
    • Sun W, Wei X, Kesavan K, Garrington TP, Fan R, et al. (2003) MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src. Mol Cell Biol 23: 2298-2308.
    • (2003) Mol Cell Biol , vol.23 , pp. 2298-2308
    • Sun, W.1    Wei, X.2    Kesavan, K.3    Garrington, T.P.4    Fan, R.5
  • 17
    • 69949095925 scopus 로고    scopus 로고
    • Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue
    • Cazares LH, Troyer D, Mendrinos S, Lance RA, Nyalwidhe JO, et al. (2009) Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue. Clin Cancer Res 15: 5541-5551.
    • (2009) Clin Cancer Res , vol.15 , pp. 5541-5551
    • Cazares, L.H.1    Troyer, D.2    Mendrinos, S.3    Lance, R.A.4    Nyalwidhe, J.O.5
  • 18
    • 79954507936 scopus 로고    scopus 로고
    • MiR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells
    • Noonan EJ, Place RF, Basak S, Pookot D, Li LC, (2010) miR-449a causes Rb-dependent cell cycle arrest and senescence in prostate cancer cells. Oncotarget 1: 349-358.
    • (2010) Oncotarget , vol.1 , pp. 349-358
    • Noonan, E.J.1    Place, R.F.2    Basak, S.3    Pookot, D.4    Li, L.C.5
  • 19
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435: 834-838.
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3    Alvarez-Saavedra, E.4    Lamb, J.5
  • 20
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, et al. (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103: 2257-2261.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3    Ambs, S.4    Cimmino, A.5
  • 21
    • 77957966270 scopus 로고    scopus 로고
    • Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase
    • Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, et al. (2010) Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell 18: 329-340.
    • (2010) Cancer Cell , vol.18 , pp. 329-340
    • Aggarwal, P.1    Vaites, L.P.2    Kim, J.K.3    Mellert, H.4    Gurung, B.5
  • 22
    • 67749117934 scopus 로고    scopus 로고
    • Signal integration by JNK and p38 MAPK pathways in cancer development
    • Wagner EF, Nebreda AR, (2009) Signal integration by JNK and p38 MAPK pathways in cancer development. Nat Rev Cancer 9: 537-549.
    • (2009) Nat Rev Cancer , vol.9 , pp. 537-549
    • Wagner, E.F.1    Nebreda, A.R.2
  • 23
    • 0033786378 scopus 로고    scopus 로고
    • Rb function in cell-cycle regulation and apoptosis
    • Harbour JW, Dean DC, (2000) Rb function in cell-cycle regulation and apoptosis. Nat Cell Biol 2: E65-67.
    • (2000) Nat Cell Biol , vol.2
    • Harbour, J.W.1    Dean, D.C.2
  • 24
    • 0031951182 scopus 로고    scopus 로고
    • Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
    • Lundberg AS, Weinberg RA, (1998) Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol Cell Biol 18: 753-761.
    • (1998) Mol Cell Biol , vol.18 , pp. 753-761
    • Lundberg, A.S.1    Weinberg, R.A.2
  • 25
    • 67651154718 scopus 로고    scopus 로고
    • MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells
    • Xu T, Zhu Y, Xiong Y, Ge YY, Yun JP, et al. (2009) MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells. Hepatology 50: 113-121.
    • (2009) Hepatology , vol.50 , pp. 113-121
    • Xu, T.1    Zhu, Y.2    Xiong, Y.3    Ge, Y.Y.4    Yun, J.P.5
  • 26
    • 52149104245 scopus 로고    scopus 로고
    • XIAP regulates bi-phasic NF-kappaB induction involving physical interaction and ubiquitination of MEKK2
    • Winsauer G, Resch U, Hofer-Warbinek R, Schichl YM, de Martin R, (2008) XIAP regulates bi-phasic NF-kappaB induction involving physical interaction and ubiquitination of MEKK2. Cell Signal 20: 2107-2112.
    • (2008) Cell Signal , vol.20 , pp. 2107-2112
    • Winsauer, G.1    Resch, U.2    Hofer-Warbinek, R.3    Schichl, Y.M.4    de Martin, R.5
  • 27
    • 77952099246 scopus 로고    scopus 로고
    • Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2
    • Shan C, Xu F, Zhang S, You J, You X, et al. (2010) Hepatitis B virus X protein promotes liver cell proliferation via a positive cascade loop involving arachidonic acid metabolism and p-ERK1/2. Cell Res 20: 563-575.
    • (2010) Cell Res , vol.20 , pp. 563-575
    • Shan, C.1    Xu, F.2    Zhang, S.3    You, J.4    You, X.5
  • 28
    • 40649111377 scopus 로고    scopus 로고
    • A chemical method for fast and sensitive detection of DNA synthesis in vivo
    • Salic A, Mitchison TJ, (2008) A chemical method for fast and sensitive detection of DNA synthesis in vivo. Proc Natl Acad Sci U S A 105: 2415-2420.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2415-2420
    • Salic, A.1    Mitchison, T.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.