Four polymorphisms of the CAPN 10 gene and their relationship to polycystic ovary syndrome susceptibility: A meta-analysis

Clinical Endocrinology

Volumn 76, Issue 3, 2012, Pages 431-438

  Huang, Miaoling ^a   Xiao, Jianpeng ^b   Zhao, Xiaomiao ^a   Liu, Changhao ^a   Chen, Qing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b Guangdong Institute of Public Health   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN 10;

ALLELE; ARTICLE; DISEASE PREDISPOSITION; GENE DELETION; GENETIC ASSOCIATION; HETEROZYGOTE; HUMAN; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMATIC REVIEW;

ALLELES; CALPAIN; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENES, DOMINANT; GENES, RECESSIVE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MODELS, GENETIC; ODDS RATIO; POLYCYSTIC OVARY SYNDROME; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84863032786     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2011.04218.x     Document Type: Article

References (35)

1. Franks, S., (1995) Polycystic ovary syndrome. New England Journal of Medicine, 333, 853-861.
2. Jones, M.R., Chua, A., Chen, Y.D., et al. (2011) Harnessing expression data to identify novel candidate genes in polycystic ovary syndrome. PLoS ONE, 6, e20120.
3. Perez, M.S., Cerrone, G.E., Benencia, H., et al. (2008) Polymorphism in CYP11alpha and CYP17 genes and the etiology of hyperandrogenism in patients with polycystic ovary syndrome. Medicina (B Aires), 68, 129-134. (Pubitemid 351753302)
4. Petry, C.J., Ong, K.K., Michelmore, K.F., et al. (2005) Association of aromatase (CYP 19) gene variation with features of hyperandrogenism in two populations of young women. Human Reproduction, 20, 1837-1843. (Pubitemid 40932365)
5. Zhu, J.Q., Zhu, L., Liang, X.W., et al. (2010) Demethylation of LHR in dehydroepiandrosterone-induced mouse model of polycystic ovary syndrome. Molecular Human Reproduction, 16, 260-266.
6. Zhang, X., Fu, L., Zhang, Q., et al. (2011) Association of TRB3 Q84R polymorphism with polycystic ovary syndrome in Chinese women. Reproductive Biology and Endocrinology, 9, 46.
7. Christopoulos, P., Mastorakos, G., Gazouli, M., et al. (2010) Study of association of IRS-1 and IRS-2 genes polymorphisms with clinical and metabolic features in women with polycystic ovary syndrome. Is there an impact? Gynecological Endocrinology, 26, 698-703.
8. Lin, Y., Xing, F.Q., Ou, Z.Y., et al. (2011) Relation between insulin resistance and insulin receptor gene methylation in the endometrium of patients with polycystic ovary syndrome. Nan Fang Yi Ke Da Xue Xue Bao, 31, 867-870.
9. Roldan, B., San, M.J., &, Escobar-Morreale, H.F., (2004) Genetic basis of metabolic abnormalities in polycystic ovary syndrome: implications for therapy. American Journal of Pharmacogenomics, 4, 93-107. (Pubitemid 38560316)
10. Hanis, C.L., Boerwinkle, E., Chakraborty, R., et al. (1996) A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nature Genetics, 13, 161-166. (Pubitemid 26000435)
11. Suzuki, K., Hata, S., Kawabata, Y., et al. (2004) Structure, activation, and biology of calpain. Diabetes, 53 (Suppl 1), S12-S18. (Pubitemid 38168687)
12. Baier, L.J., Permana, P.A., Yang, X., et al. (2000) A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. Journal Of Clinical Investigation, 106, R69-R73.
13. Sreenan, S.K., Zhou, Y.P., Otani, K., et al. (2001) Calpains play a role in insulin secretion and action. Diabetes, 50, 2013-2020. (Pubitemid 33643667)
14. Weedon, M.N., Schwarz, P.E., Horikawa, Y., et al. (2003) Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility. American Journal Of Human Genetics, 73, 1208-1212. (Pubitemid 37414233)
15. Zhang, R.Y., Bai, J.L., Yi, H.G., et al. (2009) Association between calpain-10 gene polymorphism and risk of type 2 diabetes mellitus: a meta analysis. Zhonghua Liu Xing Bing Xue Za Zhi, 30, 850-856.
16. Tsuchiya, T., Schwarz, P.E., Bosque-Plata, L.D., et al. (2006) Association of the calpain-10 gene with type 2 diabetes in Europeans: results of pooled and meta-analyses. Molecular Genetics And Metabolism, 89, 174-184. (Pubitemid 44205480)
17. Ehrmann, D.A., Schwarz, P.E., Hara, M., et al. (2002) Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 87, 1669-1673. (Pubitemid 34615255)
18. Escobar-Morreale, H.F., Peral, B., Villuendas, G., et al. (2002) Common single nucleotide polymorphisms in intron 3 of the calpain-10 gene influence hirsutism. Fertility And Sterility, 77, 581-587. (Pubitemid 34177215)
19. Gonzalez, A., Abril, E., Roca, A., et al. (2002) Comment: CAPN10 alleles are associated with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 87, 3971-3976. (Pubitemid 34879556)
20. Gonzalez, A., Abril, E., Roca, A., et al. (2003) Specific CAPN10 gene haplotypes influence the clinical profile of polycystic ovary patients. Journal of Clinical Endocrinology and Metabolism, 88, 5529-5536. (Pubitemid 37452766)
21. Haap, M., Machicao, F., Stefan, N., et al. (2005) Genetic determinants of insulin action in polycystic ovary syndrome. Experimental and Clinical Endocrinology and Diabetes, 113, 275-281. (Pubitemid 40868183)
22. Haddad, L., Evans, J.C., Gharani, N., et al. (2002) Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 87, 2606-2610. (Pubitemid 34655321)
23. Lee, J.Y., Lee, W.J., Hur, S.E., et al. (2009) 111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women. Fertility And Sterility, 92, 830-833.
24. Marquez, J.L., Pacheco, A., Valdes, P., et al. (2008) Association between CAPN10 UCSNP-43 gene polymorphism and polycystic ovary syndrome in Chilean women. Clinica Chimica Acta, 398, 5-9.
25. Unsal, T., Konac, E., Yesilkaya, E., et al. (2009) Genetic polymorphisms of FSHR, CYP17, CYP1A1, CAPN10, INSR, SERPINE1 genes in adolescent girls with polycystic ovary syndrome. Journal of Assisted Reproduction and Genetics, 26, 205-216.
26. Vollmert, C., Hahn, S., Lamina, C., et al. (2007) Calpain-10 variants and haplotypes are associated with polycystic ovary syndrome in Caucasians. American Journal of Physiology. Endocrinology and Metabolism, 292, E836-E844. (Pubitemid 46411062)
27. Wiltgen, D., Furtado, L., Kohek, M.B., et al. (2007) CAPN10 UCSNP-43, UCSNP-19 and UCSNP-63 polymorphisms and metabolic syndrome in polycystic ovary syndrome. Gynecological Endocrinology, 23, 173-178. (Pubitemid 46570217)
28. Yilmaz, M., Yurtcu, E., Demirci, H., et al. (2009) Calpain 10 gene single-nucleotide 44 polymorphism may have an influence on clinical and metabolic features in patients with polycystic ovary syndrome. Journal of Endocrinological Investigation, 32, 13-17.
29. Elbein, S.C., Chu, W., Ren, Q., et al. (2002) Role of calpain-10 gene variants in familial type 2 diabetes in Caucasians. Journal of Clinical Endocrinology and Metabolism, 87, 650-654. (Pubitemid 34158232)
30. Saez, M.E., Gonzalez-Sanchez, J.L., Ramirez-Lorca, R., et al. (2008) The CAPN10 gene is associated with insulin resistance phenotypes in the Spanish population. PLoS ONE, 3, e2953.
31. Corbould, A., (2008) Insulin resistance in skeletal muscle and adipose tissue in polycystic ovary syndrome: are the molecular mechanisms distinct from type 2 diabetes? Panminerva Medica, 50, 279-294.
32. DeUgarte, C.M., Bartolucci, A.A., &, Azziz, R., (2005) Prevalence of insulin resistance in the polycystic ovary syndrome using the homeostasis model assessment. Fertility And Sterility, 83, 1454-1460. (Pubitemid 40615820)
33. Carmina, E., &, Lobo, R.A., (2004) Use of fasting blood to assess the prevalence of insulin resistance in women with polycystic ovary syndrome. Fertility And Sterility, 82, 661-665. (Pubitemid 39243189)
34. Shima, Y., Nakanishi, K., Odawara, M., et al. (2003) Association of the SNP-19 genotype 22 in the calpain-10 gene with elevated body mass index and hemoglobin A1c levels in Japanese. Clinica Chimica Acta, 336, 89-96. (Pubitemid 37324758)
35. Minelli, C., Thompson, J.R., Tobin, M.D., et al. (2004) An integrated approach to the meta-analysis of genetic association studies using Mendelian randomization. American Journal Of Epidemiology, 160, 445-452. (Pubitemid 39166977)