The role of programmed cell death in streptozotocin-induced early diabetic nephropathy

Journal of Endocrinological Investigation

Volumn 34, Issue 9 SUPPL., 2011, Pages

  Wu, W H ^a,b   Zhang, M P ^b   Zhang, F ^b   Liu, F ^a   Hu, Z X ^a   Hu, Q D ^b   Yan, X Y ^a   Huang, S M ^a  

^a SICHUAN UNIVERSITY   (China)

^b SOUTHWEST MEDICAL UNIVERSITY   (China)

Author keywords

Autophagy; Beclin1; Early diabetic nephropathy; Microtubule associated protein 1 light chain3; Programmed cell death

Indexed keywords

BECLIN 1; CITRIC ACID; MICROTUBULE ASSOCIATED PROTEIN 1; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONTROLLED STUDY; DIABETIC NEPHROPATHY; ELECTRON MICROSCOPY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY PARENCHYMA; LIGHT CHAIN; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; STREPTOZOCIN DIABETES; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; HUMANS; KIDNEY; MALE; MICROTUBULE-ASSOCIATED PROTEINS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN;

EID: 84863021698     PISSN: 03914097     EISSN: 17208386     Source Type: Journal    
DOI: 10.3275/7741     Document Type: Article

References (30)

1. KDOQI. KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetic and chronic Kidney Disease. Am J Kidney Dis 2007, 49 (Suppl 2): S12-154.
2. Fomoni A, Ijaz A, Tejada T, Lenz O. Role of inflammation in diabetic nephropathy. Curr Diabetes Rev 2008, 4: 10-7. (Pubitemid 351216880)
3. Susztak K, Raff AC, Schiffer M, Böttinger EP. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 2006, 55: 225-33. (Pubitemid 43343319)
4. Conradt B. Genetic control of programmed cell death during animal development. Annu Rev Genet 2009, 43: 493-523.
5. Shimizu S, Kanaseki T, Mizushima N, et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004, 6: 1221-8. (Pubitemid 39625121)
6. Fujitani Y, Ueno T, Watada H. Autophagy in health and disease. 4. The role of pancreatic beta-cell autophagy in health and diabetes. Am J Physiol Cell Physiol 2010, 299: C1-6.
7. Lin LT, Dawson PW, Richardson CD. Viral interactions with macroautophagy: a double-edged sword. Virology 2010, 402: 1-10.
8. Boya P, Mellén MA, de la Rosa EJ. How autophagy is related to programmed cell death during the development of the nervous system. Biochem Soc Trans 2008, 36: 813-7.
9. Ferraro E, Cecconi F. Autophagic and apoptotic response to stress signals in mammalian cells. Arch Biochem Biophys 2007, 462: 210-9. (Pubitemid 46856320)
10. Meijer AJ, Codogno P. Autophagy: a sweet process in diabetes. Cell Metab 2008, 8: 275-6.
11. Han SY, Jee YH, Han KH, et al. An imbalance between matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 contributes to the development of early diabetic nephropathy. Nephrol Dial Transplant 2006, 21: 2406-16. (Pubitemid 44644511)
12. Zhang Y, Chen B, Hou XH, et al. Effects of mycophenolate mofetil, valsartan and their combined therapy on preventing podocyte loss in early stage of diabetic nephropathy in rats. Chin Med (Engl) 2007, 120: 988-95. (Pubitemid 46902179)
13. Diskin T, Tal-Or P, Erlich S, et al. Closed head injury induces up-regulation of Beclin 1 at the cortical site of injury. J Neurotrauma 2005, 22: 750-62. (Pubitemid 40995307)
14. Klionsky DJ, Abeliovich H, Agostinis P, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008, 4: 151-75.
15. Susztak K, Raff AC, Schiffer M, Böttinger EP. Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy. Diabetes 2006, 55: 225-33. (Pubitemid 43343319)
16. Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J 2007, 26: 1749-60. (Pubitemid 46624042)
17. Liu G, Sun Y, Li Z, et al. Apoptosis induced by endoplasmic reticulum stress involved in diabetic kidney disease. Biochem Biophys Res Commun 2008, 370: 651-6.
18. Schleicher SM, Moretti L, Varki V, Lu B. Progress in the unraveling of the endoplasmic reticulum stress/autophagy pathway and cancer: implications for future therapeutic approaches. Drug Resist Updat 2010, 13: 79-86.
19. Mori H, Inoki K, Masutani K, et al. The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential. Biochem Biophys Res Commun 2009, 384: 471-5.
20. Díaz-Troya S, Pérez-Pérez ME, Florencio FJ, Crespo JL. The role of TOR in autophagy regulation from yeast to plants and mammals. Autophagy 2008, 4: 851-65.
21. Wu J, Dang Y, Su W, et al. Molecular cloning and characterization of rat LC3A and LC3B - two novel markers of autophagosome. Biochem Biophys Res Commun 2006, 339: 437-42. (Pubitemid 41697567)
22. Funderburk SF, Wang QJ, Yue Z. The Beclin 1-VPS34 complex - at the crossroads of autophagy and beyond. Trends Cell Biol 2010, 20: 355-62.
23. Maiuri MC, Zalckvar E, Kimchi A, Kroemer G. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 2007, 8: 741-52. (Pubitemid 47312826)
24. Hartleben B, Gödel M, Meyer-Schwesinger C, et al. Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest 2010, 120: 1084-96.
25. Tanida I, Ueno T, Kominami E. LC3 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 2004, 36: 2503-18. (Pubitemid 39119762)
26. Inoki K. Role of TSC-mTOR pathway in diabetic nephropathy. Diabetes Res Clin Pract 2008, 82: S59-62.
27. Haneda M, Koya D, Kikkawa R. Cellular mechanisms in the development and progression of diabetic nephropathy:Activation of the DAG-PKC-ERK pathway. Am J Kidney Dis 2001 (Suppl 1), 38: S178-81. (Pubitemid 32927639)
28. Jiang H, Cheng D, Liu W, Peng J, Feng J. Protein kinase C inhibits autophagy and phosphorylates LC3. Biochem Biophys Res Commun 2010, 395: 471-6.
29. Yan L, Vatner DE, Kim SJ, et al. Autophagy in chronically ischemic myocadium. Proc Natl Acad Sci U S A 2005, 102: 13807-12.
30. Hamacher-Brady A, Brady NR, Gottlieb RA. Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes. J Biol Chem 2006, 281: 29776-87. (Pubitemid 44536987)