The high-level expression of human tissue plasminogen activator in the milk of transgenic mice with hybrid gene locus strategy

Molecular Biotechnology

Volumn 50, Issue 2, 2012, Pages 137-144

  Zhou, Yanrong ^a   Lin, Yanli ^a   Wu, Xiaojie ^a   Xiong, Fuyin ^a   Lv, Yuemeng ^a   Zheng, Tao ^a   Huang, Peitang ^a   Chen, Hongxing ^a  

^a BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

Author keywords

Milk; Tissue plasminogen activator; Transgenic mice; Whey acidic protein

Indexed keywords

ACIDIC PROTEINS; BROAD APPLICATION; CODING SEQUENCES; EXPRESSION LEVELS; EXPRESSION VECTORS; HIGH LEVEL EXPRESSION; HUMAN LACTOFERRIN; HUMAN TISSUES; LARGE-SCALE PRODUCTION; MAMMARY GLAND; MILK; PHARMACEUTICAL PROTEIN; RECOMBINANT PROTEIN; TISSUE PLASMINOGEN ACTIVATOR; TRANSGENE; TRANSGENE EXPRESSION; TRANSGENIC ANIMALS; TRANSGENIC MICE;

CODES (SYMBOLS); MAMMALS; PROTEINS; TISSUE;

GENE EXPRESSION;

LACTOFERRIN; TISSUE PLASMINOGEN ACTIVATOR;

ARTICLE; CODON; GENE LOCUS; HYBRID GENE; MAMMARY GLAND; MILK; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; TRANSGENE; TRANSGENIC MOUSE;

ANIMALS; FEMALE; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HUMANS; MAMMARY GLANDS, ANIMAL; MICE; MICE, TRANSGENIC; MILK; MILK PROTEINS; TISSUE PLASMINOGEN ACTIVATOR; TRANSGENES;

ANIMALIA; MUS; MUS MUSCULUS;

EID: 84863016909     PISSN: 10736085     EISSN: 15590305     Source Type: Journal    
DOI: 10.1007/s12033-011-9428-0     Document Type: Article

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