Age-related topographical metabolic signatures for the rat gastrointestinal contents

Journal of Proteome Research

Volumn 11, Issue 2, 2012, Pages 1397-1411

  Tian, Yuan ^a,b   Zhang, Limin ^a   Wang, Yulan ^a   Tang, Huiru ^a  

^a Wuhan National Laboratory for Optoelectronics   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

1H NMR spectroscopy; feces; gastrointestinal content; gut microbiota; metabonomics; multivariate statistical analysis

Indexed keywords

AMINO ACID; ARABINOXYLAN; BILE ACID; CARBOHYDRATE; CHOLINE; CREATINE; LACTIC ACID; OXOACID; SHORT CHAIN FATTY ACID; TAURINE; URACIL; UROCANIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CECUM; COLON; FECES; GASTROINTESTINAL ABSORPTION; GASTROINTESTINAL TRACT; ILEUM; INTESTINE FLORA; JEJUNUM; MALE; METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STOMACH JUICE;

AGE FACTORS; ANIMALS; DISCRIMINANT ANALYSIS; FECES; GASTROINTESTINAL CONTENTS; GASTROINTESTINAL TRACT; INTESTINES; LEAST-SQUARES ANALYSIS; METABOLOME; MULTIVARIATE ANALYSIS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PRINCIPAL COMPONENT ANALYSIS; RATS;

ANIMALIA; MAMMALIA; RATTUS;

EID: 84863012692     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr2011507     Document Type: Article

References (59)

1. Andersson, A. F.; Lindberg, M.; Jakobsson, H.; Backhed, F.; Nyren, P.; Engstrand, L. Comparative analysis of human gut microbiota by barcoded pyrosequencing PLoS One 2008, 3 (7) e2836
2. Hooper, L. V.; Gordon, J. I. Commensal host-bacterial relationships in the gut Science 2001, 292 (5519) 1115-8
3. Martin, F. P. J.; Dumas, M. E.; Wang, Y. L.; Legido-Quigley, C.; Yap, I. K. S.; Tang, H. R.; Zirah, S.; Murphy, G. M.; Cloarec, O.; Lindon, J. C.; Sprenger, N.; Fay, L. B.; Kochhar, S.; van Bladeren, P.; Holmes, E.; Nicholson, J. K. A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model Mol. Syst. Biol. 2007, 3, 112
4. Li, M.; Wang, B.; Zhang, M.; Rantalainen, M.; Wang, S.; Zhou, H.; Zhang, Y.; Shen, J.; Pang, X.; Zhang, M.; Wei, H.; Chen, Y.; Lu, H.; Zuo, J.; Su, M.; Qiu, Y.; Jia, W.; Xiao, C.; Smith, L. M.; Yang, S.; Holmes, E.; Tang, H.; Zhao, G.; Nicholson, J. K.; Li, L.; Zhao, L. Symbiotic gut microbes modulate human metabolic phenotypes Proc. Natl. Acad. Sci. U.S.A. 2008, 105 (6) 2117-22
5. Walter, J.; Britton, R. A.; Roos, S. Host-microbial symbiosis in the vertebrate gastrointestinal tract and the Lactobacillus reuteri paradigm Proc. Natl. Acad. Sci. U.S.A. 2011, 108 (suppl 1) 4645-52
6. Backhed, F.; Ley, R. E.; Sonnenburg, J. L.; Peterson, D. A.; Gordon, J. I. Host-bacterial mutualism in the human intestine Science 2005, 307 (5717) 1915-20
7. Turnbaugh, P. J.; Hamady, M.; Yatsunenko, T.; Cantarel, B. L.; Duncan, A.; Ley, R. E.; Sogin, M. L.; Jones, W. J.; Roe, B. A.; Affourtit, J. P.; Egholm, M.; Henrissat, B.; Heath, A. C.; Knight, R.; Gordon, J. I. A core gut microbiome in obese and lean twins Nature 2009, 457 (7228) 480-U7
8. Turnbaugh, P. J.; Ley, R. E.; Mahowald, M. A.; Magrini, V.; Mardis, E. R.; Gordon, J. I. An obesity-associated gut microbiome with increased capacity for energy harvest Nature 2006, 444 (7122) 1027-31
9. Xu, J.; Gordon, J. I. Honor thy symbionts Proc. Natl. Acad. Sci. U.S.A. 2003, 100 (18) 10452-9
10. Macpherson, A.; Khoo, U. Y.; Forgacs, I.; PhilpottHoward, J.; Bjarnason, I. Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria Gut 1996, 38 (3) 365-75
11. Wilson, I. D.; Nicholson, J. K. The role of gut microbiota in drug response Curr. Pharm. Des. 2009, 15 (13) 1519-23
12. O'Keefe, S. J. D.; Ou, J. H.; Aufreiter, S.; O'Connor, D.; Sharma, S.; Sepulveda, J.; Fukuwatari, T.; Shibata, K.; Mawhinney, T. Products of the colonic microbiota mediate the effects of diet on colon cancer risk J. Nutr. 2009, 139 (11) 2044-8
13. Stepankova, R.; Tonar, Z.; Bartova, J.; Nedorost, L.; Rossman, P.; Poledne, R.; Schwarzer, M.; Tlaskalova-Hogenova, H. Absence of microbiota (germ-free conditions) accelerates the atherosclerosis in ApoE-deficient mice fed standard low cholesterol diet J. Atheroscler. Thromb. 2010, 17 (8) 796-804
14. Sanz, Y.; Santacruz, A.; Gauffin, P. Gut microbiota in obesity and metabolic disorders Proc. Nutr. Soc. 2010, 69 (3) 434-41
15. Rhee, S. H.; Pothoulakis, C.; Mayer, E. A. Principles and clinical implications of the brain-gut-enteric microbiota axis Nat. Rev. Gastroenterol. Hepatol. 2009, 6 (5) 306-14
16. Hopkins, M. J.; Sharp, R.; Macfarlane, G. T. Age and disease related changes in intestinal bacterial popular-ions assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles Gut 2001, 48 (2) 198-205
17. Mackie, R. I.; Sghir, A.; Gaskins, H. R. Developmental microbial ecology of the neonatal gastrointestinal tract Am. J. Clin. Nutr. 1999, 69 (5) 1035S-45S
18. 1H NMR spectroscopy and multivariate data analysis J. Proteome Res. 2005, 4 (4) 1324-9
19. 1H NMR spectroscopy J. Proteome Res. 2007, 6 (10) 3944-51
20. Wang, Y.; Cloarec, O.; Tang, H.; Lindon, J. C.; Noimes, E.; Kochhar, S.; Nicholson, J. K. Magic angle spinning NMR and H-1-P-31 heteronuclear statistical total correlation spectroscopy of intact human gut biopsies Anal. Chem. 2008, 80 (4) 1058-66
21. Saric, J.; Wang, Y.; Li, J.; Coen, M.; Utzinger, J.; Marchesi, J. R.; Keiser, J.; Veselkov, K.; Lindon, J. C.; Nicholson, J. K.; Holmes, E. Species variation in the fecal metabolome gives insight into differential gastrointestinal function J. Proteome Res. 2008, 7 (1) 352-60
22. Wu, J. F.; An, Y. P.; Yao, J. W.; Wang, Y. L.; Tang, H. R. An optimized sample preparation method for NMR-based faecal metabonomic analysis Analyst 2010, 135 (5) 1023-30
23. Marchesi, J. R.; Holmes, E.; Khan, F.; Kochhar, S.; Scanlan, P.; Shanahan, F.; Wilson, I. D.; Wang, Y. L. Rapid and noninvasive metabonomic characterization of inflammatory bowel disease J. Proteome Res. 2007, 6 (2) 546-51
24. Naruse, S.; Ishiguro, H.; Ko, S. B. H.; Yoshikawa, T.; Yamamoto, T.; Yamamoto, A.; Futakuchi, S.; Goto, H.; Saito, Y.; Takahashi, S. Fecal pancreatic elastase: a reproducible marker for severe exocrine pancreatic insufficiency J. Gastroenterol. 2006, 41 (9) 901-8
25. Ahlquist, D. A.; Skoletsky, J. E.; Boynton, K. A.; Harrington, J. J.; Mahoney, D. W.; Pierceall, W. E.; Thibodeau, S. N.; Shuber, A. P. Colorectal cancer screening by detection of altered human DNA in stool: Feasibility of a multitarget assay panel Gastroenterology 2000, 119 (5) 1219-27
26. Xiao, C.; Hao, F.; Qin, X.; Wang, Y.; Tang, H. An optimized buffer system for NMR-based urinary metabonomics with effective pH control, chemical shift consistency and dilution minimization Analyst 2009, 134 (5) 916-25
27. Dai, H.; Xiao, C.; Liu, H.; Tang, H. Combined NMR and LC-MS analysis reveals the metabonomic changes in salvia miltiorrhiza bunge induced by water depletion J. Proteome Res. 2010, 9 (3) 1460-75
28. Dai, H.; Xiao, C.; Liu, H.; Hao, F.; Tang, H. Combined NMR and LC-DAD-MS analysis reveals comprehensive metabonomic variations for three phenotypic cultivars of salvia miltiorrhiza bunge J. Proteome Res. 2010, 9 (3) 1565-78
29. Viel, S.; Capitani, D.; Mannina, L.; Segre, A. Diffusion-ordered NMR spectroscopy: A versatile tool for the molecular weight determination of uncharged polysaccharides Biomacromolecules 2003, 4 (6) 1843-7
30. Johnson, C. S. Diffusion ordered nuclear magnetic resonance spectroscopy: principles and applications Prog. Nucl. Magn. Res. Spectrom. 1999, 34, 203-56
31. Trygg, J.; Wold, S. Orthogonal projections to latent structures (O-PLS) J. Chemom. 2002, 16 (3) 119-28
32. Eriksson, L.; Trygg, J.; Wold, S. CV-ANOVA for significance testing of PLS and OPLS (R) models J. Chemom. 2008, 22 (11-12) 594-600
33. 1H NMR data sets Anal. Chem. 2005, 77 (5) 1282-9
34. Fan, T. W. M.; Lane, A. N. Structure-based profiling of metabolites and isotopomers by NMR Prog. Nucl. Magn. Res. Spectrom. 2008, 52 (2-3) 69-117
35. Pastell, H.; Tuomainen, P.; Virkki, L.; Tenkanen, M. Step-wise enzymatic preparation and structural characterization of singly and doubly substituted arabinoxylo-oligosaccharides with non-reducing end terminal branches Carbohydr. Res. 2008, 343 (18) 3049-57
36. Wu, G. Y. Intestinal mucosal amino acid catabolism J. Nutr. 1998, 128 (8) 1249-52
37. Karppinen, S.; Liukkonen, K.; Aura, A. M.; Forssell, P.; Poutanen, K. In vitro fermentation of polysaccharides of rye, wheat and oat brans and inulin by human faecal bacteria J. Sci. Food Agric. 2000, 80 (10) 1469-76
38. Sakata, T. Influence of insoluble dietary fiber on bacterial metabolism in the large intestine Foods Food Ingredients J. Jpn. 2004, 209, 4
39. Grubb, B. R. Avian cecum-role of glucose and volatile fatty acids in transepithelial ion-transport Am. J. Physiol. 1991, 260 (5) G703-10
40. Degregorio, R. M.; Tucker, R. E.; Mitchell, G. E.; Gill, W. W. Acetate and propionate production in the cecum and proximal colon of lambs J. Anim. Sci. 1984, 58 (1) 203-7
41. Bourriaud, C.; Robins, R. J.; Martin, L.; Kozlowski, F.; Tenailleau, E.; Cherbut, C.; Michel, C. Lactate is mainly fermented to butyrate by human intestinal microfloras but inter-individual variation is evident J. Appl. Microbiol. 2005, 99 (1) 201-12
42. Pelech, S. L.; Vance, D. E. Regulation of phosphatidylcholine biosynthesis Biochim. Biophys. Acta 1984, 779 (2) 217-51
43. Zeisel, S. H.; Dacosta, K. A.; Youssef, M.; Hensey, S. Conversion of dietary choline to trimethylamine and dimethylamine in rats-dose-response relationship J. Nutr. 1989, 119 (5) 800-4
44. Sheard, N. F.; Zeisel, S. H. An invitro study of choline uptake by intestine from neonatal and adult rats Pediatr. Res. 1986, 20 (8) 768-72
45. Orsenigo, M. N.; Faelli, A.; De Biasi, S.; Sironi, C.; Laforenza, U.; Paulmichl, M.; Tosco, M. Jejunal creatine absorption: What is the role of the basolateral membrane? J. Membr. Biol. 2005, 207 (3) 183-95
46. Peral, M. J.; Garcia-Delgado, M.; Calonge, M. L.; Duran, J. M.; De La Horra, M. C.; Wallimann, T.; Speer, O.; Ilundain, A. A. Human, rat and chicken small intestinal Na+-Cl - creatine transporter: functional, molecular characterization and localization J. Physiol. 2002, 545 (1) 133-44
47. Huxtable, R. J. Physiological actions of taurine Physiol. Rev. 1992, 72 (1) 101-63
48. Dietschy, J. M.; Salomon, H. S. Siperste.Md, Bile acid metabolism. 1. studies on mechanisms of intestinal transport J. Clin. Invest. 1966, 45 (6) 832
49. Kim, K. S. Characterization of absorption process of taurine across rat small intestine Arch. Pharm. Res. 1983, 6 (2) 109-14
50. Schram, E.; Crokaert, R. Etude du metabolisme de la taurine chezle rat-formation de sulfate Biochim. Biophys. Acta 1957, 26 (2) 300-8
51. Kimura, T.; Kim, K. S.; Sezaki, H. Effect of taurine on drug absorption from the rat gastrointestinal-tract J. Pharmacobiodyn. 1981, 4 (1) 35-41
52. Merheb, M.; Daher, R. T.; Nasrallah, M.; Sabra, R.; Ziyadeh, F. N.; Barada, K. Taurine intestinal absorption and renal excretion test in diabetic patients Diabetes Care 2007, 30 (10) 2652-4
53. Himukai, M.; Konno, T.; Hoshi, T. Age-dependent change in intestinal absorption of dipeptides and their constituent amino acids in the guinea pig Pediatr. Res. 1980, 14 (11) 1272-5
54. Barada, K. A.; Atallah, J. B.; Nassar, C. F. Age influence on intestinal taurine transport in mice Comp. Biochem. Physiol. A: Physiol. 1997, 118 (1) 159-63
55. Sharafuddin, M.; Nassar, G. M.; Nassar, C. F. Taurine transport across the small-intestine of adult and suckling rats Comp. Biochem. Physiol. A: Physiol. 1988, 91 (1) 33-6
56. Crittenden, R.; Karppinen, S.; Ojanen, S.; Tenkanen, M.; Fagerstrom, R.; Matto, J.; Saarela, M.; Mattila-Sandholm, T.; Poutanen, K. In vitro fermentation of cereal dietary fibre carbohydrates by probiotic and intestinal bacteria J. Sci. Food Agric. 2002, 82 (8) 781-9
57. Yajima, M.; Nakayama, M.; Hatano, S.; Yamazaki, K.; Aoyama, Y.; Yajima, T.; Kuwata, T. Bacterial translocation in neonatal rats: The relation between intestinal flora, translocated bacteria, and influence of milk J. Pediatr. Gastroenterol. Nutr. 2001, 33 (5) 592-601
58. Mitsuoka, T.; Kaneuchi, C. Ecology of bifidobacteria Am. J. Clin. Nutr. 1977, 30 (11) 1799-810
59. Woodmansey, E. J. Intestinal bacteria and ageing J. Appl. Microbiol. 2007, 102 (5) 1178-86