Expanding the limits of isonitrile-mediated amidations: On the remarkable stereosubtleties of macrolactam formation from synthetic seco -cyclosporins

Journal of the American Chemical Society

Volumn 134, Issue 4, 2012, Pages 2378-2384

  Wu, Xiangyang ^a   Stockdill, Jennifer L ^a   Park, Peter K ^a   Danishefsky, Samuel J ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOND-FORMING REACTIONS; COUPLING REAGENTS; CYCLOSPORIN A; PREORGANIZATION; SHEDDING LIGHT; SINGLE PRECURSORS; STEREOCHEMICAL CHANGES; SYNTHETIC APPROACH; TYPE II;

AMIDES;

CARBOXYLATION;

AMIDE; CYCLOSPORIN A; ISONITRILE DERIVATIVE; MACROCYCLIC LACTAM;

ACYLATION; AMIDATION; ARTICLE; CHEMICAL BOND; STEREOCHEMISTRY;

AMIDES; CYCLOSPORINS; LACTAMS, MACROCYCLIC; MOLECULAR STRUCTURE; NITRILES; STEREOISOMERISM;

EID: 84863011662     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja2103372     Document Type: Article

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