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Volumn 31, Issue 2, 2012, Pages 171-179

Effects of Mycobacterium tuberculosis ESAT-6/CFP-10 fusion protein on the autophagy function of mouse macrophages

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6; HYBRID PROTEIN; RAPAMYCIN;

EID: 84863011279     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2011.1290     Document Type: Article
Times cited : (45)

References (38)
  • 2
    • 33748776564 scopus 로고    scopus 로고
    • C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis
    • DOI 10.1126/science.1131167
    • Champion, P.A., Stanley, S.A., Champion, M.M., Brown, E.J., and Cox, J.S. (2006). C-Terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis. Science 313, 1632-1636. (Pubitemid 44414036)
    • (2006) Science , vol.313 , Issue.5793 , pp. 1632-1636
    • DiGiuseppe Champion, P.A.1    Stanley, S.A.2    Champion, M.M.3    Brown, E.J.4    Cox, J.S.5
  • 5
    • 75649145030 scopus 로고    scopus 로고
    • Autophag in immunity against Mycobacterium tuberculosis: A model system to dissect immunological roles of autophagy
    • Deretic, V., Delgado, M., Vergne, I., Master, S., De Haro, S., Ponpuak, M., and Singh, S. (2009a). Autophag in immunity against Mycobacterium tuberculosis: a model system to dissect immunological roles of autophagy. Curr Top Microbiol Immunol 335, 169-188.
    • (2009) Curr Top Microbiol Immunol , vol.335 , pp. 169-188
    • Deretic, V.1    Delgado, M.2    Vergne, I.3    Master, S.4    De Haro, S.5    Ponpuak, M.6    Singh, S.7
  • 6
    • 67649607465 scopus 로고    scopus 로고
    • Autophagy, immunity, and microbial adaptations
    • Deretic, V., and Levine, B. (2009b). Autophagy, immunity, and microbial adaptations. Cell Host Microbe 5, 527-549.
    • (2009) Cell Host Microbe , vol.5 , pp. 527-549
    • Deretic, V.1    Levine, B.2
  • 9
    • 37849052202 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis secretory proteins CFP-10, ESAT-6 and the CFP10:ESAT6 complex inhibit lipopolysaccharide-induced NF-kappaB transactivation by downregulation of reactive oxidative species (ROS) production
    • Ganguly, N., Giang, P.H., Gupta, C., Basu, S.K., and Siddiqui, I. (2008a). Mycobacterium tuberculosis secretory proteins CFP-10, ESAT-6 and the CFP10:ESAT6 complex inhibit lipopolysaccharide-induced NF-kappaB transactivation by downregulation of reactive oxidative species (ROS) production. Immunol Cell Biol 86, 98-106.
    • (2008) Immunol Cell Biol , vol.86 , pp. 98-106
    • Ganguly, N.1    Giang, P.H.2    Gupta, C.3    Basu, S.K.4    Siddiqui, I.5
  • 10
    • 54349104640 scopus 로고    scopus 로고
    • Role of M. tuberculosis RD-1 region encoded secretory proteins in protective response and virulence
    • Ganguly, N., Siddiqui, I., and Sharma, P. (2008b). Role of M. tuberculosis RD-1 region encoded secretory proteins in protective response and virulence. Tuberculosis (Edinb) 88, 510-517.
    • (2008) Tuberculosis (Edinb) , vol.88 , pp. 510-517
    • Ganguly, N.1    Siddiqui, I.2    Sharma, P.3
  • 11
    • 77951878738 scopus 로고    scopus 로고
    • Lactic acid bacteria enhance autophagic ability of mononuclear phagocytes by increasing Th1 autophagypromoting cytokine (IFN-gamma) and nitric oxide (NO) levels and reducing Th2 autophagy-restraining cytokines (IL-4 and IL-13) in response to Mycobacterium tuberculosis antigen
    • Ghadimi, D., de Vrese, M., Heller, K.J., and Schrezenmeir, J. (2010). Lactic acid bacteria enhance autophagic ability of mononuclear phagocytes by increasing Th1 autophagypromoting cytokine (IFN-gamma) and nitric oxide (NO) levels and reducing Th2 autophagy-restraining cytokines (IL-4 and IL-13) in response to Mycobacterium tuberculosis antigen. Int Immunopharmacol 10, 694-706.
    • (2010) Int Immunopharmacol , vol.10 , pp. 694-706
    • Ghadimi, D.1    De Vrese, M.2    Heller, K.J.3    Schrezenmeir, J.4
  • 12
    • 0942290453 scopus 로고    scopus 로고
    • Individual RD1 -region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis
    • DOI 10.1046/j.1365-2958.2003.03844.x
    • Guinn, K.M., Hickey, M.J., Mathur, S.K., Zakel, K.L., Grotzke, J.E., Lewinsohn, D.M., Smith, S., and Sherman, D.R. (2004). Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis. Mol Microbiol 51, 359-370. (Pubitemid 38142126)
    • (2004) Molecular Microbiology , vol.51 , Issue.2 , pp. 359-370
    • Guinn, K.M.1    Hickey, M.J.2    Mathur, S.K.3    Zakel, K.L.4    Grotzke, J.E.5    Lewinsohn, D.M.6    Smith, S.7    Sherman, D.R.8
  • 13
    • 10944253145 scopus 로고    scopus 로고
    • Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
    • DOI 10.1016/j.cell.2004.11.038, PII S0092867404011067
    • Gutierrez, M.G., Master, S.S., Singh, S.B., Taylor, G.A., Colombo, M.I., and Deretic V. (2004). Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 119, 753-766. (Pubitemid 40017683)
    • (2004) Cell , vol.119 , Issue.6 , pp. 753-766
    • Gutierrez, M.G.1    Master, S.S.2    Singh, S.B.3    Taylor, G.A.4    Colombo, M.I.5    Deretic, V.6
  • 14
    • 77955884684 scopus 로고    scopus 로고
    • Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins
    • Itakura, E., and Mizushima, N. (2010). Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy 6, 764-776.
    • (2010) Autophagy , vol.6 , pp. 764-776
    • Itakura, E.1    Mizushima, N.2
  • 15
    • 62049084947 scopus 로고    scopus 로고
    • Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
    • Jagannath, C., Lindsey, D.R., Dhandayuthapani, S., Xu, Y., Hunter, R.L. Jr., and Eissa, N.T. (2009). Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nat Med 15, 267-276.
    • (2009) Nat Med , vol.15 , pp. 267-276
    • Jagannath, C.1    Lindsey, D.R.2    Dhandayuthapani, S.3    Xu, Y.4    Hunter Jr., R.L.5    Eissa, N.T.6
  • 16
    • 57349158670 scopus 로고    scopus 로고
    • Enhanced and enduring protection against tuberculosis by recombinant BCG-Ag85C and its association with modulation of cytokine profile in lung
    • Jain, R., Dey, B., Dhar, N, Rao, V., Singh, R., Gupta, U.D., Katoch, V.M., Ramanathan, V.D., and Tyagi, A.K. (2008). Enhanced and enduring protection against tuberculosis by recombinant BCG-Ag85C and its association with modulation of cytokine profile in lung. PLoS One 3, e3869.
    • (2008) PLoS One , vol.3
    • Jain, R.1    Dey, B.2    Dhar, N.3    Rao, V.4    Singh, R.5    Gupta, U.D.6    Katoch, V.M.7    Ramanathan, V.D.8    Tyagi, A.K.9
  • 17
    • 77957119308 scopus 로고    scopus 로고
    • Innate immunity to mycobacteria: Vitamin D and autophagy
    • Jo, E.K. (2010). Innate immunity to mycobacteria: vitamin D and autophagy. Cell Microbiol 12, 1026-1035.
    • (2010) Cell Microbiol , vol.12 , pp. 1026-1035
    • Jo, E.K.1
  • 18
    • 2142752480 scopus 로고    scopus 로고
    • Cellular autophagy: Surrender, avoidance and subversion by microorganisms
    • DOI 10.1038/nrmicro865
    • Kirkegaard, K., Taylor, M.P., and Jackson, W.T. (2004). Cellular autophagy: surrender, avoidance and subversion by microorganisms. Nat Rev Microbiol 2, 301-314. (Pubitemid 39490100)
    • (2004) Nature Reviews Microbiology , vol.2 , Issue.4 , pp. 301-314
    • Kirkegaard, K.1    Taylor, M.P.2    Jackson, W.T.3
  • 19
    • 14044277429 scopus 로고    scopus 로고
    • The molecular machinery of autophagy: Unanswered questions
    • DOI 10.1242/jcs.01620
    • Klionsky, D.J. (2005). The molecular machinery of autophagy: unanswered questions. J Cell Sci 118, 7-18. (Pubitemid 40277100)
    • (2005) Journal of Cell Science , vol.118 , Issue.1 , pp. 7-18
    • Klionsky, D.J.1
  • 21
    • 34548700796 scopus 로고    scopus 로고
    • Unveiling the roles of autophagy in innate and adaptive immunity
    • DOI 10.1038/nri2161, PII NRI2161
    • Levine, B., and Deretic, V. (2007). Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol 7, 767-777. (Pubitemid 47480305)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.10 , pp. 767-777
    • Levine, B.1    Deretic, V.2
  • 23
    • 3042723794 scopus 로고    scopus 로고
    • Autophagy: Molecular mechanisms, physiological functions and relevance in human pathology
    • Mariño, G., and López-Otín, C. (2004). Autophagy: molecular mechanisms, physiological functions and relevance in human pathology. Cell Mol Life Sci 61, 1439-1454. (Pubitemid 38858351)
    • (2004) Cellular and Molecular Life Sciences , vol.61 , Issue.12 , pp. 1439-1454
    • Marino, G.1    Lopez-Otin, C.2
  • 24
    • 0027318976 scopus 로고
    • Pathogenesis of tuberculosis: Interaction of Mycobacterium tuberculosis with macrophages
    • McDonough, K.A., Kress, Y., and Bloom, B.R. (1993). Pathogenesis of tuberculosis: interaction of Mycobacterium tuberculosis with macrophages. Infect Immun 61, 2763-2773. (Pubitemid 23182267)
    • (1993) Infection and Immunity , vol.61 , Issue.7 , pp. 2763-2773
    • McDonough, K.A.1    Kress, Y.2    Bloom, B.R.3
  • 25
    • 33745117262 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis H37Rv ESAT-6-CFP-10 complex formation confers thermodynamic and biochemical stability
    • DOI 10.1111/j.1742-4658.2006.05166.x
    • Meher, A.K., Bal, N.C., Chary, K.V., and Arora, A. (2006). Mycobacterium tuberculosis H37Rv ESAT-6-CFP-10 complex formation confers thermodynamic and biochemical stability. FEBS J 273, 1445-1462. (Pubitemid 44029108)
    • (2006) FEBS Journal , vol.273 , Issue.7 , pp. 1445-1462
    • Mener, A.K.1    Bal, N.C.2    Chary, K.V.R.3    Arora, A.4
  • 26
    • 3042706674 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis complex transcriptome of attenuation
    • DOI 10.1016/j.tube.2004.02.002, PII S1472979204000216
    • Mostowy, S., Cleto, C., Sherman, D.R., and Behr, M.A. (2004). The Mycobacterium tuberculosis complex transcriptome of attenuation. Tuberculosis (Edinb) 84, 197-204. (Pubitemid 38857852)
    • (2004) Tuberculosis , vol.84 , Issue.3-4 , pp. 197-204
    • Mostowy, S.1    Cleto, C.2    Sherman, D.R.3    Behr, M.A.4
  • 27
    • 65249187333 scopus 로고    scopus 로고
    • Enhancing immunity through autophagy
    • Munz, C. (2009). Enhancing immunity through autophagy. Annu Rev Immunol 27, 423-449.
    • (2009) Annu Rev Immunol , vol.27 , pp. 423-449
    • Munz, C.1
  • 28
    • 18044394244 scopus 로고    scopus 로고
    • The Trojan horse: Survival tactics of pathogenic mycobacteria in macrophages
    • DOI 10.1016/j.tcb.2005.03.009
    • Nguyen, L., and Pieters, J. (2005). The Trojan horse: survival tactics of pathogenic mycobacteria in macrophages. Trends Cell Biol 15, 269-276. (Pubitemid 40603896)
    • (2005) Trends in Cell Biology , vol.15 , Issue.5 , pp. 269-276
    • Nguyen, L.1    Pieters, J.2
  • 29
    • 31944448733 scopus 로고    scopus 로고
    • Bacterial evasion of the autophagic defense system
    • DOI 10.1016/j.mib.2005.12.007, PII S1369527405002018, Host-Microbe Interactions: Bacteria
    • Ogawa, M., and Sasakawa, C. (2006). Bacterial evasion of the autophagic defense system. Curr Opin Microbiol 9, 62-68. (Pubitemid 43186019)
    • (2006) Current Opinion in Microbiology , vol.9 , Issue.1 , pp. 62-68
    • Ogawa, M.1    Sasakawa, C.2
  • 30
    • 34249012130 scopus 로고    scopus 로고
    • Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages
    • DOI 10.1038/ni1468, PII NI1468
    • Pathak, S.K., Basu, S., Basu, K.K, Banerjee, A., Pathak, S., Bhattacharyya, A., Kaisho, T., Kundu, M., and Basu, J. (2007). Direct extracellular between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages. Nat Immunol 8, 610-618. (Pubitemid 46785125)
    • (2007) Nature Immunology , vol.8 , Issue.6 , pp. 610-618
    • Pathak, S.K.1    Basu, S.2    Basu, K.K.3    Banerjee, A.4    Pathak, S.5    Bhattacharyya, A.6    Kaisho, T.7    Kundu, M.8    Basu, J.9
  • 32
    • 0037077299 scopus 로고    scopus 로고
    • Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6·CFP-10 complex. Implications for pathogenesis and virulence
    • DOI 10.1074/jbc.M201625200
    • Renshaw, P.S., Panagiotidou, P., Whelan, A., Gordon, S.V., Hewinson, R.G., Williamson, R.A., and Carr, M.D. (2002). Conclusive evidence that the major T-cell antigens of the Mycobacterium tuberculosis complex ESAT-6 and CFP-10 form a tight, 1:1 complex and characterization of the structural properties of ESAT-6, CFP-10, and the ESAT-6*CFP-10 complex. Implications for pathogenesis and virulence. J Biol Chem 24, 21598-21603. (Pubitemid 34952307)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.24 , pp. 21598-21603
    • Renshaw, P.S.1    Panagiotidou, P.2    Whelan, A.3    Gordon, S.V.4    Glyn Hewinson, R.5    Williamson, R.A.6    Carr, M.D.7
  • 33
    • 0037711625 scopus 로고    scopus 로고
    • Cytoplasmic bacteria can be targets for autophagy
    • DOI 10.1046/j.1462-5822.2003.00292.x
    • Rich, K.A., Burkett, C., and Webster, P. (2003). Cytoplasmic bacteria can be targets for autophagy. Cell Microbiol 5, 455-468. (Pubitemid 36818107)
    • (2003) Cellular Microbiology , vol.5 , Issue.7 , pp. 455-468
    • Rich, K.A.1    Burkett, C.2    Webster, P.3
  • 34
    • 0035432383 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis: Here today, and here tomorrow
    • DOI 10.1038/35085034
    • Russell, D.G. (2001). Mycobacterium tuberculosis: here today, and here tomorrow. Nat Rev Mol Cell Biol 2, 569-577. (Pubitemid 33674008)
    • (2001) Nature Reviews Molecular Cell Biology , vol.2 , Issue.8 , pp. 569-577
    • Russell, D.G.1
  • 35
    • 33344475671 scopus 로고    scopus 로고
    • Autophagy in innate and adaptive immunity against intracellular pathogens
    • DOI 10.1007/s00109-005-0014-4
    • Schmid, D., Dengjel, J., Schoor, O., Stevanovic, S., and Münz, C. (2006). Autophagy in innate and adaptive immunity against intracellular pathogens. J Mol Med 84, 194-202. (Pubitemid 43291008)
    • (2006) Journal of Molecular Medicine , vol.84 , Issue.3 , pp. 194-202
    • Schmid, D.1    Dengjel, J.2    Schoor, O.3    Stevanovic, S.4    Munz, C.5
  • 37
    • 35448965809 scopus 로고    scopus 로고
    • A unique Mycobacterium ESX-1 protein co-secretes with CFP-10/ESAT-6 and is necessary for inhibiting phagosome maturation
    • DOI 10.1111/j.1365-2958.2007.05959.x
    • Xu, J., Laine, O., Masciocchi, M., Manoranjan, J., Smith, J., Du, S.J., Edwards, N., Zhu, X., Fenselau, C., and Gao, L.Y. (2007). A unique Mycobacterium ESX-1 protein cosecretes with CFP-10/ESAT-6 and is necessary for inhibiting phagosome maturation. Mol Microbiol 66, 787-800. (Pubitemid 47621863)
    • (2007) Molecular Microbiology , vol.66 , Issue.3 , pp. 787-800
    • Xu, J.1    Laine, O.2    Masciocchi, M.3    Manoranjan, J.4    Smith, J.5    Du, S.J.6    Edwards, N.7    Zhu, X.8    Fenselau, C.9    Gao, L.-Y.10
  • 38
    • 77956298743 scopus 로고    scopus 로고
    • Recombinant Mycobacterium smegmatis expressing an ESAT6-CFP10 fusion protein induces anti-mycobacterial immune responses and protects against Mycobacterium tuberculosis challenge in mice
    • Zhang, H., Peng, P., Miao, S., Zhao, Y., Mao, F., Wang, L., Bai, Y., Xu, Z., Wei, S., and Shi, C. (2010). Recombinant Mycobacterium smegmatis expressing an ESAT6-CFP10 fusion protein induces anti-mycobacterial immune responses and protects against Mycobacterium tuberculosis challenge in mice. Scand J Immunol 72, 349-357.
    • (2010) Scand J Immunol , vol.72 , pp. 349-357
    • Zhang, H.1    Peng, P.2    Miao, S.3    Zhao, Y.4    Mao, F.5    Wang, L.6    Bai, Y.7    Xu, Z.8    Wei, S.9    Shi, C.10


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