The change in conjugated linoleic acid concentration in blood of Japanese fed a conjugated linoleic acid diet

Journal of Nutritional Science and Vitaminology

Volumn 57, Issue 5, 2011, Pages 364-371

  Sato, Kenta ^a   Shinohara, Nahoko ^a   Honma, Taro ^a   Ito, Junya ^a   Arai, Tatsuya ^a   Nosaka, Naohisa ^b   Aoyama, Toshiaki ^b   Tsuduki, Tsuyoshi ^a   Ikeda, Ikuo ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b The Nisshin OilliO Group   (Japan)

Author keywords

CLA; Conjugated fatty acid; Conjugated linoleic acid; Human; Metabolism

Indexed keywords

CONJUGATED LINOLEIC ACID;

ADULT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; FAT INTAKE; FATTY ACID BLOOD LEVEL; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FEMALE; HUMAN; HUMAN EXPERIMENT; JAPANESE; LIPID DIET; MALE; NORMAL HUMAN;

ADULT; DIETARY FATS; DOUBLE-BLIND METHOD; ERYTHROCYTES; FEMALE; HUMANS; INTESTINAL ABSORPTION; JAPAN; KINETICS; LINOLEIC ACIDS, CONJUGATED; LIPOPROTEINS; MALE; REPRODUCIBILITY OF RESULTS; YOUNG ADULT;

ANIMALIA;

EID: 84863011234     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.57.364     Document Type: Article

References (32)

1. Azain MJ. 2004. Role of fatty acids in adipocyte growth and development. J Anim Sci 82: 916-924.
2. Ip C, Scimeca JA, Thompson H. 1995. Effect of timing and duration of dietary conjugated linoleic acid on mammary cancer prevention. Nutr Cancer 24: 241-247.
3. O'Shea M, Bassaganya-Riera J, Mohede ICM. 2004. Immunomodulatory properties of conjugated linoleic acid. Am J Clin Nutr 79: 1199S-1206S.
4. Kelly O, Cashman KD. 2004. The effect of conjugated linoleic acid on calcium absorption and bone metabolism and composition in adult ovariectomised rats. Prostaglandins Leukot Essent Fatty Acids 71: 295-301.
5. Whigham LD, O'Shea M, Mohede ICM, Walaski HP, Atkinson RL. 2004. Safety profile of conjugated linoleic acid in a 12-month trial in obese humans. Food Chem Toxicol 42: 1701-1709.
6. Iwata T, Kamegai T, Yamauchi-Sato Y, Ogawa A, Kasai M, Aoyama T, Kondo K. 2007. Safety of dietary conjugated linoleic acid (CLA) in a 12-weeks trial in healthy overweight Japanese male volunteers. J Oleo Sci 56: 517-525.
7. Gaullier JM, Halse J, Høye K, Kristiansen K, Fagertun H, Vik H, Gudmundsen O. 2005. Supplementation with conjugated linoleic acid for 24 months is well tolerated by and reduces body fat mass in healthy, overweight humans. J Nutr 135: 778-784.
8. Sugano M, Tsujita A, Yamasaki M, Yamada K, Ikeda I, Kritchevsky D. 1997. Lymphatic recovery, tissue distribution, and metabolic effects of conjugated linoleic acid in rats. J Nutr Biochem 8: 38-43.
9. Tsuzuki T, Tokuyama Y, Igarashi M, Miyazawa T. 2004. Tumor growth suppression by α-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation. Carcinogenesis 25: 1417-1425.
10. Kelley DS, Bartolini GL, Newman JW, Vemuri M, Mackey BE. 2006. Fatty acid composition of liver, adipose tissue, spleen, and heart of mice fed diets containing t10, c12-, and c9, t11-conjugated linoleic acid. Prostaglandins Leukot Essent Fatty Acids 74: 331-338.
11. Noone EJ, Roche HM, Nugent AP, Gibney MJ. 2002. The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects. Br J Nutr 88: 243-251.
12. Kimura T, Nakagawa K, Kubota H, Kojima Y, Goto Y, Yamagishi K, Oita S, Oikawa S, Miyazawa T. 2007. Food-grade mulberry powder enriched with 1-deoxynojirimycin suppresses the elevation of postprandial blood glucose in humans. J Agric Food Chem 55: 5869-5874.
13. Kawakami Y, Tsuzuki T, Nakagawa K, Miyazawa T. 2007. Distribution of tocotrienols in rats fed a rice bran tocotrienol concentrate. Biosci Biotechnol Biochem 71: 464-471.
14. Tsuduki T, Nakamura Y, Honma T, Nakagawa K, Kimura T, Ikeda I, Miyazawa T. 2009. Intake of 1-deoxynojirimycin suppresses lipid accumulation through activation of the β-oxidation system in rat liver. J Agric Food Chem 57: 11024-11029.
15. Havel RJ, Eder HA, Bragdon JH. 1955. The Distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 34: 1345-1353.
16. Bligh EG, Dyer WJ. 1959. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917.
17. Igarashi M, Tsuzuki T, Kambe T, Miyazawa T. 2004. Recommended methods of fatty acid methylester preparation for conjugated dienes and trienes in food and biological samples. J Nutr Sci Vitaminol 50: 121-128.
18. Tsuzuki T, Kawakami Y, Abe R, Nakagawa K, Koba K, Imamura J, Iwata T, Ikeda I, Miyazawa T. 2006. Conjugated linolenic acid is slowly absorbed in rat intestine, but quickly converted to conjugated linoleic acid. J Nutr 136: 2153-2159.
19. Moloney F, Yeow T, Mullen A, Nolan JN, Roche HM. 2004. Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. Am J Clin Nutr 80: 887-895.
20. Zlatanos SN, Laskaridis K, Sagredos A. 2008. Conjugated linoleic acid content of human plasma. Lipids Health Dis 7: 34.
21. Ou L, Ip C, Lisafeld B, Ip MM. 2007. Conjugated linoleic acid induces apoptosis of murine mammary tumor cells via Bcl-2 loss. Biochem Biophys Res Commun 18: 1044-1049.
22. Kemp MQ, Jeffy BD, Romagnolo DF. 2003. Conjugated linoleic acid inhibits cell proliferation through a p53-dependent mechanism: effects on the expression of G1-restriction points in breast and colon cancer cells. J Nutr 133: 3670-3677.
23. Igarashi M, Miyazawa T. 2001. The growth inhibitory effect of conjugated linoleic acid on a human hepatoma cell line, HepG2, is induced by a change in fatty acid metabolism, but not the facilitation of lipid peroxidation in the cells. Biochim Biophys Acta 1530: 162-171.
24. Berlin NI, Lawrence JH, Elmlinger PJ. 1957. Recent advances in the knowledge of total red cell volume, production and destruction. Blood 12: 147-164.
25. Tsuzuki T, Igarashi M, Iwata T, Sato-Yamauchi Y, Yamamoto T, Ogita K, Suzuki T, Miyazawa T. 2004. Oxidation rate of conjugated linoleic acid and conjugated linolenic acid is slowed by triacylglycerol esterfication and α-tocopherol. Lipids 39: 475-480.
26. Demizieux L, Degrace P, Gresti J, Loreau O, Noel JP, Chardigny JM, Sebedio JL, Clouet P. 2002. Conjugated linoleic acid isomers in mitochondria: evidence for an alteration of fatty acid oxidation. J Lipid Res 43: 2112-2122.
27. Blankson H, Stakkestad JA, Fagertun H, Thom E, Wadstein J, Gudmundsen O. 2000. Conjugated linoleic acid reduces body fat mass in overweight and obese humans. J Nutr 130: 2943-2948.
28. Mougios V, Matsakas A, Petridou A, Ring S, Sagredos A, Melissopoulou A, Tsigilis N, Nikolaidis M. 2001. Effect of supplementation with conjugated linoleic acid on human serum lipids and body fat. J Nutr Biochem 12: 585-594.
29. Gaullier JM, Halse J, Høye K, Kristiansen K, Fagertun H, Vik H, Gudmundsen O. 2004. Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans. Am J Clin Nutr 79: 1118-1125.
30. Smedman A, Vessby B. 2001. Conjugated linoleic acid supplementation in humans-metabolic effects. Lipids 36: 773-781.
31. Riserus U, Arner P, Brismar K, Vessby B. 2002. Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer specific insulin resistance in obese men with the metabolic syndrome. Diabetes Care 25: 1516-1521.
32. Halade GV, Rahman MM, Fernandes G. 2010. Differential effects of conjugated linoleic acid isomers in insulinresistant female C57Bl/6J mice. J Nutr Biochem 21: 332-337.